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Course
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Scientific Disciplinary Sector Code
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Contact Hours
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Exercise Hours
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Laboratory Hours
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Type of Activity
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Language
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90096 -
Physics, statistics and information technology
(objectives)
The objectives of this integrated course consist of:
To provide students with the fundamentals of physics necessary to carry out their future activity, with particular regard to the understanding of the physical principles underlying the characteristic phenomena of applied physics in the medical context and the basis of Operation and use of the instrumentation necessary for the control and detection of these phenomena.
To acquire the student the ability to statistically analyse the main phenomena of biomedical sciences by acquiring knowledge of the basic principles of biostatistics and the ability to use the main techniques and tools of analysis of data.
Provide the basic knowledge needed to use a calculator.
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APPLIED PHYSICS
(objectives)
At the end of the course the student must have acquired basic knowledge of principles of physics necessary to understand how the major systems of the human body works and the correct usage of biomedical instruments with particular attention to applications regarding this degree course.
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Indovina Iole
( syllabus)
Mechanics
Chapter 1: Introduction, Measurement, Estimating
1.4: Measurement and Uncertainty; Significant Figures
1.5: Units, Standards, and SI Units
1.6: Converting Units
1.8: Dimensions and Dimensional Analysis
Chapter 2: Describing Motion: Kinematics in One Dimension
2.1: References Frames and Displacement
2.2: Average Velocity
2.3: Instantaneous Velocity
2.4: Acceleration
2.5: Motion at Constant Acceleration
Chapter 3: Kinematics in Two Dimensions; Vectors
3.1: Vectors and Scalars
3.2: Addition of Vectors-Graphical Methods
3.3: Subtraction of Vectors and Multiplication of a Vector by a Scalar
3.4: Adding Vectors by Components
Chapter 4: Dynamics: Newton's Laws of Motion
4.1: Force
4.2: Newton's First Law of Motion
4.3: Mass
4.4: Newton's Second Law of Motion
4.5: Newton's Third Law of Motion
4.6: Weight-The Force of Gravity; and the Normal Force
4.7: Solving Problems with Newton's Laws: Free-Body Diagrams
4.8: Problems Involving Friction, Inclines
4.9: Problem Solving-A General Approach
Chapter 5: Circular Motion; Gravitation
5.1: Kinematics of Uniform Circular Motion
5.2: Dynamics of Uniform Circular Motion
5.6: Newton's Law of Universal Gravitation
Chapter 6: Work and Energy
6.1: Work Done by a Constant Force
6.3: Kinetic Energy and the Work-Energy Principle
6.4: Potential Energy
6.5: Conservative and Nonconservative Forces
6.6: Mechanical Energy and its Conservation
6.7: Problem Solving Using Conservation of Mechanical Energy
6.8: Other Forms of Energy: Energy Transformations and the Law of Conservation of Energy
6.10: Power
Chapter 7: Linear Momentum
7.1: Momentum and Its Relation to Force
7.2: Conservation of Momentum
7.8: Center of Mass (CM)
7.10: Center of Mass and Translational Motion
Chapter 9: Static Equilibrium; Elasticity and Fracture
9.1: The Conditions for Equilibrium
9.2: Solving Statics Problems
9.3: Applications to Muscles and Joints
9.4: Stability and Balance
9.5: Elasticity; Stress and Strain
9.6: Fracture
Chapter 14: Heat
14.1 Heat as Energy Transfer
14.2 Internal Energy
14.3: Specific Heat
14.4: Calorimetry
14.5: Latent Heat
14.6: Heat Transfer: Conduction
Fluids
Chapter 10: Fluids
10.1: Phases of Matter
10.2: Density and Specific Gravity
10.3: Pressure in Fluids
10.4: Atmospheric Pressure Gauge Pressure
10.5: Pascal's Principle
10.6: Measurement of Pressure; Gauges and the Barometer
10.7: Buoyancy and Archimedes' Principle
Vibrations and Waves
Chapter 11: Vibrations and Waves
11.7: Wave Motion
11.8: Types of Waves: Transverse and Longitudinal
11.9: Energy Transported by Waves
11.10: Intensity Related to Amplitude and Frequency
Chapter 12: Sound
12-1 Characteristics of Sound
12-2 Intensity of Sound: Decibels
12-7 Doppler Effect
Electricity and Magnetism
Chapter 16: Electric Charge and Electric Field
16.1: Static Electricity; Electric Charge and its Conservation
16.2: Electric Charge in the Atom
16.3: Insulators and Conductors
16.4: Induced Charge; the Electroscope
16.5: Coulomb's Law
16.6: Solving Problems Involving Coulomb's Law and Vectors
16.7: The Electric Field
16.8: Field Lines
16.9: Electric Fields and Conductors
Chapter 17: Electric Potential
17.1: Electric Potential Energy and Potential Differences
17.2: Relation between Electric Potential and Electric Field
17.3: Equipotential Lines
17.4: The Electron Volt, a Unit of Energy
17.5: Electric Potential Due to Point Charges
17.7: Capacitance
17.8: Dielectrics
17.9: Storage of Electric Energy
Chapter 18: Electric Currents
18.1: The Electric Battery
18.2: The Electric Current
18.3: Ohm's Law: Resistance and Resistors
18.4: Resistivity
18.5: Electric Power
Chapter 19: DC Circuits
19.1: EMF and Terminal Voltage
19.2: Resistors in Series and in Parallel
19.3: Kirchhoff's Rules
19.4: EMFs in Series and in Parallel; Charging a Battery
19.5: Circuits Containing Capacitors in Series and in Parallel
19.6: RC Circuits-Resistor and Capacitor in Series
Chapter 22: Electromagnetic Waves
22.1: Changing Electric Fields Produce Magnetic Fields; Maxwell's Equations
22.2: Production of Electromagnetic Waves
22.3: Light as an Electromagnetic Wave and the Electromagnetic Spectrum
22.5: Energy in EM Waves
Chapter 24: The Wave Nature of Light
24.4: The Visible Spectrum and Dispersion
Chapter 25: Optical Instruments
25-11: X-Rays and X-Ray Diffraction
25-12: X-Ray Imaging and Computed Tomography (CT Scan)
( reference books)
Douglas C. Giancoli “PHYSICS: Principles with Applications” Seventh edition, Pearson Education. Inc
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2
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FIS/07
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20
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Basic compulsory activities
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ENG |
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INFORMATION TECHNOLOGY
(objectives)
The course intends to provide students with the basic knowledge to understand the essential role of Information Technology (IT) in our society, and specifically in the context of health-related technical professions.
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D'Ambrogio Andrea
( syllabus)
- Introduction to Information Systems
- Information System types
- The lifecycle of Information Systems
- Database and Database Management System (DBMS)
( reference books)
Understanding Computers: Today and Tomorrow, 16th ed, Deborah Morley and Charles S. Parker, Cengage Learning - Pentalibro a Roma
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2
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INF/01
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20
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-
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Basic compulsory activities
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ENG |
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MEDICAL STATISTICS
(objectives)
The Medical Statistics course aims to introduce students to the logic of statistical thinking and its application in everyday life. The exposition of the topics will be oriented towards concrete problems of analysis and research, starting from schematic examples and then confronting real situations taken from the medical literature.
The course aims to provide students with the necessary statistical tools to describe and analyze data, extract useful information and make informed decisions.
Particular emphasis will be placed on statistical reasoning, interpretation and decision-making. To this end, more emphasis will be placed on conceptual understanding than on mechanical calculation, also in light of the wide choice of software available for analysis. The theory will be explained through practical exercises and didactic cases.
In the final part of the course we will move on to the demonstration of use of some contemporary Software Suites in order to provide an operational basis for executing descriptive statistics and low-level inferential, in the belief that knowing firsthand to perform these simple tasks is the best way to open up to a conscious understanding of scientific literature.
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Weltert Luca Paolo
( syllabus)
The first part of the course will introduce the logic of statistics and experimental design.
The concepts of probability calculation and combinatorial calculation will be introduced or recalled; although theoretically already in possession of the student, these steps are fundamental and will be used in the continuation of the course. In this phase the main probability distributions will be treated, including the binomial distribution, the Poisson distribution and the standard Normal and Normal distributions, but more than the single mathematical process,we will try making the student aware of the deep motivation of the medical statistics, as a science, and its application in practice, as well as the risks of its incorrect understanding.
In the second part of the course the descriptive statistics and its methodology will be addressed. It will be shown how to recognize the type of data and how to summarize them in appropriate indexes.
The student will learn how to calculate position measurements (mean, median, fashion), variability (variance, standard deviation), coefficient of variation (CV), percentiles and their use. It will also make extensive use of practical examples to define a good descriptive statistic and a defective or deceptive descriptive statistic.
In the final part of the course the general principles of statistical inference will be treated.
Cases of sample distribution, type I and II errors, power of a test and operating curve will be introduced. We will then move on to parametric tests - Student's t-test, ANOVA with 1 and 2 classification criteria, non-parametric tests: - Wilcoxon test, Mann-Whitney test, Kruskal-Wallis test, Friedman test, median test, chi-square test, Fisher exact test. We will also provide the basic concepts of regression and analysis of time dependent variability with mention of Kaplann Meyer functions, log rank and Cox regression.
( reference books)
1) Notes of the lessons
2) Stanton A. Glantz: Statistics for Bio-medical disciplines - ed. McGraw-Hill
3) Sidney Siegel, N. John Castellan Jr.: - Non parametric statistics - ed. McGraw-Hill
4) Resources and links from the Internet with particular reference to the use of the PubMEd portal
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2
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MED/01
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20
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Basic compulsory activities
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ENG |
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DATA PROCESSING SYSTEMS
(objectives)
The course intends to provide students with the basic knowledge to understand the role of Information Systems and their lifecycle, specifically focusing on database management systems.
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D'Ambrogio Andrea
( syllabus)
- Introduction to Information Systems
- Information System types
- The lifecycle of Information Systems
- Database and Database Management System (DBMS)
( reference books)
Understanding Computers: Today and Tomorrow, 16th ed, Deborah Morley and Charles S. Parker, Cengage Learning - Pentalibro a Roma
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2
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ING-INF/05
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20
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-
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Core compulsory activities
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ENG |
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90097 -
Biology biochemistry and genetics
(objectives)
At the end of the integrated course of biology, applied Physics, biochemistry the student must be able to describe the morphological and physiological characteristics of the cells, the metabolic processes that contribute to the normal functioning of the organism through the understanding of the biochemical phenomena regulating human life and their clinical modifications. It will also have to understand the basics of physics, with a particular insight into fluid dynamics.
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BIOCHEMISTRY
(objectives)
At the end of the course the student must be able to identify the states of the matter and the significance of the chemical solutions and concentrations; it must also be able to know the organic and inorganic composition of the human organism, the general characters and the biological role of the main elements of organic chemistry.
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Mei Giampiero
( syllabus)
A – Fundamentals of Chemistry:
Atomic structure. Definition of oxides, acids, bases and salts. Examples. The valence. Covalent and hydrogen bonds. The properties of water. Osmosis. pH. Molar concentration of solutes. The fundamental chemical groups of organic molecules.
B – Fundamentals of structural Biochemistry:
Proteins structure and function. Enzymes. Carbohydrates. Fatty acids. Vitamins and hormones. Nucleic acids.
C – Fundamentals of methabolic processes:
Reducing power: NADH, NADPH, FADH2. Introduction to metabolism: Glycolysis. Krebs cycle. Fatty acid catabolism. The respiratory chain.
( reference books)
"Biochemistry" D.R.Ferrier - Wolter Kluwer Edition
"Lehningher principles of biochemistry, 2017" D.L.Nelson, M.M. Cox - W.H.Freeman & Co. Ed.
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2
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BIO/10
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20
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Basic compulsory activities
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ENG |
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APPLIED BIOLOGY
(objectives)
The purpose of the course is to provide students with:
-The basic concepts of Biochemistry, involved in the structure of macromolecules (carbohydrates, proteins, lipids and nucleic acids) and biochemical events involved in cellular metabolism.
-The basic knowledge of the cellular and molecular biology of eukaryotic cells that are crucial to understand, later, the physiology, both from the cellular and tissutal perspective .
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Galardi Silvia
( syllabus)
• General characteristics of living organisms (autotrophic and heterotrophic, aerobic and anaerobic bacteria, unicellular and multicellular, eukaryotic and prokaryotic). Cell theory.
• chemical constituents of cells: water; hydrophilic, hydrophobic and amphipathic molecules
• Structure and function of biological macromolecules: carbohydrates, lipids, proteins, nucleic acids.
• Organization of the fundamental eukaryotic cell and prokaryotic. Viruses
• Cellular compartments and related functional specialization (core; ribosomes, mitochondria, chloroplasts, endoplasmic reticulum; the Golgi complex, lysosomes, cytoskeleton; vacuoles).
• Structure and general functions of cell membranes
• Diffusion, passive transport and active transport (channel protein, sodium-potassium pump, secondary active transport)
• From genotype to phenotype: DNA as genetic material, structure and function
• DNA transcription, RNA maturation.
• The genetic code: property (universality, non-ambiguity, continuity, redundancy or degeneracy) and reading mode.
• Protein biosynthesis.
• Regulation of gene expression in eukaryotes
• Cellular reproduction: cell cycle, DNA replication and mitosis.
• Regulation of the cell cycle, tumor suppressor, oncogenes
• Sexual reproduction: Meiosis
( reference books)
Essential Cell Biology, IV edition, Alberts et al, Garland and Science
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2
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BIO/13
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20
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Basic compulsory activities
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ENG |
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MEDICAL GENETICS
(objectives)
The aims of the course of Medical Genetics is to provide to students the knowledge on the main notions on inheritance of monogenic, chromosomal and multifactorial diseases.
At the end of the course the student will have to know the main methods of analysis for the diagnosis of these disorders. He should show capacity to analyse pedigrees and clinical and molecular genetic data useful for genetic counselling and to know the major kind of genetic testing and their proper use.
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Ciccacci Cinzia
( syllabus)
Basic Genetics:Definitions of Key Terms, Polymorphisms and mutations.
Principles of Genetic Transmission: Mendel's Genetic Hypothesis, The Monohybrid Crosses, Segregation of Two or More Genes, Segregation in Human Pedigrees. Blood groups Genetics
Monogenic Inheritance Models: Autosomal dominant inheritance, Autosomal recessive inheritance, X-linked inheritance, Y linked inheritance
Genetic Risk calculation and pedigrees
Genomic Imprinting
X chromosome inactivation
Chromosome: Structure and Analysis, Chromosome Pathologies
The genetics of complex diseases: Concept of Genomic biomarker, inter-individual variability, Genetic approaches to investigate complex diseases
Pharmacogenetics and Pharmacogenomics: The role of genetic variability in the response to drugs, both in terms of efficacy and toxicity
Genetic counselling
Genetics of neurologic diseases
( reference books)
"Medical Genetics" by Jorde, Carey, Bamshad.
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2
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MED/03
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20
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Basic compulsory activities
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ENG |
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90098 -
Human anatomy and physiology
(objectives)
At the end of the Integrated Course of Anatomy and Physiology the student must be able to know the anatomical terms for the microscopic and macroscopic recognition of the human body and you/he/she must be able to explain the physiological phenomena of the various organs of the human body, their dynamics integration in the apparatuses, the mechanisms of control of their functions and the contribution I fed necessary under conditions of normalcy.
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HUMAN ANATOMY
(objectives)
The aim of the corse of human anatomy is to guide student into the study of the human body and of the critical steps of embryonal development, with special attention to the morpho-functional correlations. These are necessary pre-requisites for the understanding of physiology, patho-physiology and of the interaction of chemical compounds with tissues and organs, necessary knowledge equipment for a physician. To this end, special attention will be given to the study of the microscopic anatomy of tissues and organs and to the study of neuroanatomy. On the other end the essential elements of gross and topographic anatomy of toraco-abdominal organs will be given.
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Barchi Marco
( syllabus)
LOCOMOTOR SYSTEM. Skeleton: skull, vertebral column and main bones of the trunk, superior limb, inferior limb, pectoral and girdle and pelvis. Joints structure and classification, movements. Joints: Temporo-mandibular joint, shoulder joint, intervertebral joints, sternum-clavicular joint, elbow joint, radio-ulnar joint, wrist and hand joints. Hip joint, joints of the knee, ankle and foot. Muscolar system. Axial musculature: muscle of the head and neck, extra-ocular muscles, tongue, muscle of the pharynx of vertebral column, diaphragm, muscles of the perineum and pelvic diaphragm. Appendicular musculature: muscle of the pectoral girdle and upper limb, muscles that move the harms, muscles that move the elbow, pronators and supinators muscles. Muscles of the pelvic girdle and lower limbs, muscles of the thigh and leg.
CARDIOVASCULAR SYSTEM. Heart, thoracic aorta, aortic arch, abdominal aorta. The Willi’s polygon. Coronary circulation. Main arteries of superior and inferior limbs. Venous system. Superior vena cava, inferior vena cava and their main branches in the thorax and abdomen. Main veins of the superior and inferior limbs. Generalities on the lymphatic system.
SPLANCHNOLOGY. Digestive and respiratory systems.
( reference books)
1) Martini, Timmons, Tallitsch: Human Anatomy or
2) Tortora: Human Anatomy or 3) Gray's Basic Anatomy
3) Martini Nath: Anatomy & Physiology
4) Andrew Biel, The Guide to the body (this is a suggested complementary book in addition to the above)
Students are strongly encouraged to make use of an atlas of human anatomy of their choice
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Sciamanna Giuseppe
( syllabus)
Spinal cord: segmental and internal organization: gray matter, ascending and discending tracts. Spinals nerves, plexuses and reflex arcs. Brainstem (Medulla oblungata, Pons, Mesencephalon): internal and external structure. Cranial nerves: nuclei and innervation. Diencephalon (Thalamus, Hypothalamus, Epithalamus): internal and external structure. Thalamic nuclei. Telencephanlon: internal and external structure. Anatomical and functional organization of cerebral cortex. Allocortex. Basal Ganglia. Cerebellum: internal and external structure. Ventricular system. Meninges. Brain blood vessels and dural sinuses. Sensory system: spinothalamic, tacts, fasciculus gracilis and fasciculus cuneatus tracts, spinocerebellar tracts. Pain conduction. Visual, auditory, gustatory, olfactor and limbic system. Motor system: pyramidal and extrapyramidal tracts. Motor nuclei. Autonomic nervous system: sympathetic and parasympathetic system. Enteric nervous system.
( reference books)
1) Martini, Timmons, Tallitsch: Human Anatomy or
2) Tortora: Human Anatomy or 3) Gray's Basic Anatomy
3) Martini Nath: Anatomy & Physiology
4) Andrew Biel, The Guide to the body (this is a suggested complementary book in addition to the
above)
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3
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BIO/16
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30
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Basic compulsory activities
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ENG |
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HISTOLOGY
(objectives)
The course aims to provide students with the skills necessary for the full understanding of the most important tissues of the human organism. The student must be able to acquire a correct terminology and develop skills of interpretation and application that, the graduate in Physiotherapy, will have to use in the planning and management of work activities.
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Rossi Valerio
( syllabus)
General information on cells, on tissues. Optical and electronic microscopy. Resolution limit.
Epithelial Tissue: classification and structure. Intracellular junction. Basal membrane. Skin: structure and function. Glandular epithelia: classification and structural organization of endocrine and exocrine glands. Types and methods of secretion.
Connective tissue: Cells, fibers and fundamental substance. Classification. Mucous and serous membranes. Adipose tissue
Cartilaginous tissue: cells. Composition of the extracellular matrix. Classification.
Bone tissue: Structure. Composition of the extracellular matrix and cell types. Periosteum and endosteal. Mechanisms of ossification. Bone remodeling.
Blood: Plasma and serum. Morphology and functions of corpuscular elements. Main blood values. hematopoiesis.
Lymphatic system and immune system: Lymphatic vessels. B-lymphocytes, T and NK lymphocytes. Lymphopoiesis. Primary and secondary lymphoid organs. The immune response.
Muscle tissue: Structure of skeletal, cardiac and smooth muscle cell. Characteristics of the three types of muscle.
Nervous tissue: the neuron. Glial cells. Myelinated and unmyelinated nerve fibers. General structure of the nerves.
( reference books)
Concise Histology - 1st Edition – Elsevier
Fundamentals of Anatomy & Physiology- 11st Edition - Pearson
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1
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BIO/17
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10
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Basic compulsory activities
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ENG |
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PHYSIOLOGY
(objectives)
The aim of the teaching is, starting from the knowledge of the basic concepts and the normal quantitative parameters of the bodily functions and their variations in the different conditions of dynamic engagement, to develop in the student the ability to understand the principles of the functioning of the human body. The cellular mechanisms and the integrated functions of the main organs and apparatuses aimed at the maintenance of body homeostasis will also be analyzed in the context of environmental modifications.
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Pallone Gabriele
( syllabus)
Physiology of the cell membrane: 2 hours
- Membrane transport of ions and molecules
- Membrane potential and Action Potential
Muscle Physiology: 4 hours
-Excitation and contraction of skeletal muscle tissue.
- Neuromuscular transmission and excitation-contraction coupling.
- Motor unit
Physiology of the Nervous System: 4 hours
-The Afferent Division: decoding and processing of sensory information.
-The Efferent Division: general characteristics of the motor system: involuntary, voluntary and automatic movements; spinal reflexes; the brain-encephalic control of the movement: posture and balance. Cortical control of voluntary movements. The cerebellum: general features, functions of the cerebellum. The basal ganglia: functional role.
-The Autonomic Nervous System.
- Supplementary functions of the nervous system.
Cardiovascular physiology: 4 hours
- Myocardial physiology: functional myocardial anatomy, myocardial action potentials, contraction of the heart muscle.
- Cardiac cycle
- Nervous control of cardiac activity.
- General principles of hemodynamics.
-Adjustment of circulation, blood pressure and blood flow.
- Cardiac output: principles of regulation of cardiac output.
- Cardiac tones.
The Respiratory System: 2 hours
- Pulmonary ventilation: respiratory mechanics, volumes and lung capacity. Respiratory tract
- Gaseous exchanges: diffusion of oxygen and carbon dioxide through the respiratory membrane.
-Transportation of oxygen and carbon dioxide in blood and body fluids ..
-Regulation of breathing: general principles.
-Regulation of acid-base balance: general principles.
Body fluids and renal function: 2 hours
- Functional anatomy of the kidney, function of the nephron. Glomerular filtration: general principles.
- Elaboration of glomerular filtrate: resorption and tubular secretion,
-Control of osmolarity and sodium concentration of extracellular fluid: general principles.
-Renal regulation of blood volume: general principles
The endocrine system: 2 hours
General principles of endocrinology: nature of a hormone; general picture of the endocrine glands and their hormones. Principles of general functioning of hormones.
( reference books)
-“Berne & Levy Physiology”, Sixth Updated Edition
-“Sherwood” ninth edition
-“Guyton-Hall"
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2
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BIO/09
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20
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Basic compulsory activities
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ENG |
