Degree Course: Midwifery Syllabus for A.Y. 2019/2020

Amino acids. Protein. Generalities and functions. The peptide bond and the primary sequence, secondary, tertiary and quaternary structure. Myoglobin, hemoglobin. Notes on Collagen.
Enzymes. Role and mechanism of action of enzymes. Enzymatic regulation. Covalent regulation and allosteric regulation. Isoenzymes (LDH, CPK).
Vitamins. Classification of structure and functions, water-soluble vitamins and fat-soluble vitamins, Vitamin D and calcium and phosphorous metabolism.
Metabolism General concepts. Catabolic and anabolic pathways. Bioenergetics principles. ATP: biological structure and role.
Structure and metabolism of carbohydrates. Monosaccharides, disaccharides. Reserve polysaccharides. Digestion and absorption of carbohydrates in the diet. Glycolysis: stages and regulation. Krebs cycle: general concepts, regulation. Oxidative phosphorylation and electron transport chain, outline. Energy balance of carbohydrate catabolism. Outlines on the pentose cycle and on gluconeogenesis. Glycogen metabolism.
Metabolism of amino acids. Catabolism of diet proteins and digestive enzymes. Essential and non- essential amino acids. Amino acids as precursors of nitrogen compounds. Aminoacid catabolism: transamination and deamination, destiny of the carbon skeleton. Biosynthesis of urea.
Structure and metabolism of lipids. Classification of lipids (cell lipids and reserve lipids, simple and complex lipids). Fatty acids: general structure and main fatty acids. Structure and function of triglycerides and phospholipids. Cholesterol. Digestion and absorption of lipids; plasma lipoproteins:

David L Nelson Michael M Cox. "Introduzione alla biochimica di Lehninger". David L Nelson Michael M Cox "Lehninger Principles of Biochemistry".

Basic Genetics: Definitions of Key Terms: gene, locus, allele, genotype, phenotype, haplotype, homozygous, heterozygous, haploid, diploid, dominance, recessivity, codominance, mutation, polymorphism.
Principles of Genetic Transmission: Mendel's Genetic Hypothesis, The Monohybrid and dihybrid Crosses, Segregation in Human Pedigrees, Blood groups Genetics
Monogenic Inheritance Models: Autosomal inheritance,Autosomal recessive inheritance, X-linked inheritance
Genetic Risk calculation and pedigrees
Chromosomes: Structure and Analysis, Chromosomes Pathologies
Genomic Imprinting
X-chromosome inactivation
Mitochondrial inheritance: mitochondrial DNA, pattern of inheritance
Multifactorial inheritance: polimorphisms, susceptibility genes, gene-environment interaction, association studies
Pharmacogenomics and Personalised Medicine
Genetic tests and Counselling. Outlines

Lectures in pdf format will be provided to students.
Recommended books:
“Genetica in Medicina”, by Nussbaum, McInnes, Willard. Edises
“Genetica Medica Essenziale” by Dallapiccola, Novelli. Ciceditore

Chapter1: Introduction, Measurement, Estimating

1.4: Measurement and Uncertainty; Significant Figures
1.5: Units, Standards, and SI Units
1.6: ConvertingUnits
1.8: Dimensions and DimensionalAnalysis

Chapter14:Heat

14.1 Heat as Energy Transfer
14.2 InternalEnergy
14.3: SpecificHeat
14.4: Calorimetry
14.5: Latent Heat
14.6: Heat Transfer: Conduction
14.7: Heat Transfer: Convection
14.8: Heat Transfer: Radiation

Chapter15: The Laws of Thermodynamics

15.1: The First Law of Thermodynamics
15.2: ThermodynamicProcesses and the First Law

Fluids

Chapter10:Fluids

10.1: Phases of Matter
10.2: Density and SpecificGravity
10.3: Pressure in Fluids
10.4: Atmospheric Pressure Gauge Pressure
10.5: Pascal'sPrinciple
10.6: Measurement of Pressure; Gauges and the Barometer
10.7: Buoyancy and Archimedes' Principle

Vibrations and Waves

Chapter11: Vibrations and Waves

11.7: Wave Motion
11.8: Types of Waves: Transverse and Longitudinal
11.9: EnergyTransported by Waves
11.10: IntensityRelated to Amplitude and Frequency

Chapter12: Sound

12-1 Characteristics of Sound
12-2 Intensity of Sound: Decibels
12-7 Doppler Effect



Electricity and Magnetism

Chapter16: Electric Charge and Electric Field

16.1: StaticElectricity; Electric Charge and its Conservation
16.2: Electric Charge in the Atom
16.3: Insulators and Conductors
16.4: Induced Charge; the Electroscope
16.5: Coulomb's Law
16.6: SolvingProblemsInvolvingCoulomb's Law and Vectors
16.7: The Electric Field
16.8: Field Lines
16.9: Electric Fields and Conductors

Chapter17: Electric Potential

17.1: Electric PotentialEnergy and PotentialDifferences
17.2: Relation Between Electric Potential and Electric Field
17.3: Equipotential Lines
17.4: The Electron Volt, a Unit of Energy
17.5: Electric Potential Due to Point Charges
17.7: Capacitance
17.8: Dielectrics
17.9: Storage of Electric Energy

Chapter18: Electric Currents

18.1: The Electric Battery
18.2: The Electric Current
18.3: Ohm's Law: Resistance and Resistors
18.4: Resistivity
18.5: Electric Power

Chapter19: DC Circuits

19.1: EMF and Terminal Voltage
19.2: Resistors in Series and in Parallel
19.3: Kirchhoff'sRules
19.4: EMFs in Series and in Parallel; ChargingaBattery
19.5: Circuits ContainingCapacitors in Series and in Parallel
19.6: RC Circuits-Resistor and Capacitor in Series

Douglas C. Giancoli“PHYSICS: Principleswith Applications” Seventhedition or subsequent, Pearson Education. Inc

The indicated textbook is just a reference. Students are allowed to adopt the book/books of their choice. Additional material will be provided by the instructor.

Characteristic of living cells: Cellular theory. Classification principles of living organisms.
Prokaryotic and eukaryotic cell models: classification and major structural differences.
Cell Chemistry: Macromolecules: structure, shape and function
Plasma membrane: properties and functions.
Internal organization of the cell: Cellular compartments. Cytoplasm and cytoplasmic organelles,
ribosomes, smooth and rought endoplasmic reticulum, Golgi apparatus, lysosomes, peroxisomes.
The cytoskeleton. Microtubules, intermediate filaments and microfilaments. Cilia and flagella.
Centrioles and centrosomes.
Energy conversion: Glycolysis, fermentation, cellular respiration, photosynthesis. (outline).
Mitochondria and Chloroplasts, structure and function.
Molecular basis of hereditary information: DNA replication. DNA repair and its correlation with
human diseases.
RNA, structure and function: Main types of cellular RNAs and differences with respect to DNA in
terms of molecular size, stability and biological functions. Transcription and RNA maturation.
Genetic Code and its properties. Protein synthesis: How cells read the genome
Cellular Reproduction, Mitosis and Meiosis.

Sadava, Hillis, Heller, Hacker. Elementi di Biologia e Genetica Zanichelli editore, V ed.
• Raven,Johnson, Mason, Losos, Singer. Elementi di Biologia e Genetica Piccin editore II ed.

Physiology of the cell membrane:
-Transport of ions and molecules through the cell membrane
- Membrane potential and Action Potential

Muscle Physiology:
-Excitation and contraction of skeletal muscle tissue.
- Neuromuscular transmission and excitation-contraction coupling.
- Motor unit

Physiology of the Nervous System:
-The sensory system: decoding and processing of sensory information.
-The motor system: general characteristics of the motor system: involuntary, voluntary and automatic movements; spinal reflexes; the brain-encephalic control of the movement: posture and balance. Cortical control of voluntary movements. The cerebellum: general features, functions of the cerebellum. The basal ganglia: functional role.
-The autonomic nervous system.
- Supplementary functions of the nervous system.

Cardiovascular physiology:
- Myocardial physiology: functional myocardial anatomy, myocardial action potentials, contraction of the heart muscle.
- Cardiaccycle
- Nervous control of cardiac activity.

- General principles of hemodynamics.
-Adjustment of circulation, blood pressure and blood flow.
- Cardiac output: principles of regulation of cardiac output.
- Cardiactones.



The Respiratory System:
- Pulmonary ventilation: respiratory mechanics, volumes and lung capacity. Respiratory tract
- Gaseous exchanges: diffusion of oxygen and carbon dioxide through the respiratory membrane.
-Transportation of oxygen and carbon dioxide in blood and body fluids ..
-Regulation of breathing: general principles.
-Regulation of acid-base balance: general principles.

Body fluids and renal function:
- Functional anatomy of the kidney, function of the nephron. Glomerular filtration: general principles.
- Elaboration of glomerular filtrate: resorption and tubular secretion,
-Control of osmolarity and sodium concentration of extracellular fluid: general principles.
-Renal regulation of blood volume: general principles


The endocrine system:
General principles of endocrinology: nature of a hormone; general picture of the endocrine glands and their hormones. Principles of general functioning of hormones.

-“Berne & Levy Physiology”, Sixth Updated Edition
-“Sherwood” ninthedition
-“Guyton-Hall"

LOCOMOTOR SYSTEM.(11hs)Skeleton: skull, vertebralcolumn and mainbones of the trunk, superiorlimb, inferiorlimb, pectoral and girdle and pelvis. Joints structure and classification, movements. Joints: Temporo-mandibular joint, shoulder joint, intervertebral joints, sterno-clavicular joint, elbow joint, radioulnar joints, wrist and hand joints. Hip joint, joint of the knee, ankle.Muscolar system. Axial musculature: main muscles of the head and neck, tongue, muscle of the pharynx of vertebral column, diaphragm, muscles of the perineum and pelvic diaphragm. Appendicular musculature: muscle of the pectoral girdle and upper limb, muscles that move the harms, muscles that move the elbow, pronators ansupinators. Muscles of the pelvic girdle and lower limbs: muscles that move the thigh and leg.
CARDIOVASCULAR SYSTEM (6hs). Heart, thoracic aorta, aortic arch, abdominal aorta.The Willi’s polygon. Coronary circulation. Main arteries of superior and inferior limbs. Venous system. Superior vena cava, inferior vena cava and their main branches in the thorax and abdomen.Main veins of the superior and inferior limbs. Portal circulation. Foetal circulation. Generalities on the lymphatic system.
SPLANCHNOLOGY(11hs).Systemic and microscopy anatomy of digestive, respiratory, urinary, reproductive and endocrine Systems.
NEUROANATOMY (14hs).Spinal cord: segmental and internal organization: gray matter, ascending and discending tracts. Spinals nerves, plexuses and reflex arcs. Brainstem (Medulla oblungata, Pons, Mesencephalon): internal and external structure. Cranial nerves: nuclei and innervation. Diencephalon (Thalamus, Hypothalamus, Epithalamus): internal and external structure. Thalamic nuclei. Telencephanlon: internal and external structure. Anatomical and functional organization of cerebral cortex.Allocortex. Basal Ganglia. Cerebellum: internal and external structure. Ventricular system. Meninges. Brain blood vessels and dural sinuses. Sensory system: spinothalamic, tacts, fasciculus gracilis and fasciculus cuneatus tracts, spinocerebellar tracts. Pain conduction. Visual, auditory, gustatory, olfactor and limbic system. Motor system: pyramidal and extrapyramidal tracts. Motor nuclei. Autonomic nervous system: sympathetic and parasympathetic system. Entericnervoussystem.

1. Fondamenti di Anatomia e Fisiologia IV edizione (2019)
2. Martini, Timmons, Tallitsch,:AnatomiaUmana
3. Tortora,: AnatomiaUmana,

Students are encouraged to use an Human Anatomy Atlas

LOCOMOTOR SYSTEM.(11hs)Skeleton: skull, vertebralcolumn and mainbones of the trunk, superiorlimb, inferiorlimb, pectoral and girdle and pelvis. Joints structure and classification, movements. Joints: Temporo-mandibular joint, shoulder joint, intervertebral joints, sterno-clavicular joint, elbow joint, radioulnar joints, wrist and hand joints. Hip joint, joint of the knee, ankle.Muscolar system. Axial musculature: main muscles of the head and neck, tongue, muscle of the pharynx of vertebral column, diaphragm, muscles of the perineum and pelvic diaphragm. Appendicular musculature: muscle of the pectoral girdle and upper limb, muscles that move the harms, muscles that move the elbow, pronators ansupinators. Muscles of the pelvic girdle and lower limbs: muscles that move the thigh and leg.
CARDIOVASCULAR SYSTEM (6hs). Heart, thoracic aorta, aortic arch, abdominal aorta.The Willi’s polygon. Coronary circulation. Main arteries of superior and inferior limbs. Venous system. Superior vena cava, inferior vena cava and their main branches in the thorax and abdomen.Main veins of the superior and inferior limbs. Portal circulation. Foetal circulation. Generalities on the lymphatic system.
SPLANCHNOLOGY(11hs).Systemic and microscopy anatomy of digestive, respiratory, urinary, reproductive and endocrine Systems.
NEUROANATOMY (14hs).Spinal cord: segmental and internal organization: gray matter, ascending and discending tracts. Spinals nerves, plexuses and reflex arcs. Brainstem (Medulla oblungata, Pons, Mesencephalon): internal and external structure. Cranial nerves: nuclei and innervation. Diencephalon (Thalamus, Hypothalamus, Epithalamus): internal and external structure. Thalamic nuclei. Telencephanlon: internal and external structure. Anatomical and functional organization of cerebral cortex.Allocortex. Basal Ganglia. Cerebellum: internal and external structure. Ventricular system. Meninges. Brain blood vessels and dural sinuses. Sensory system: spinothalamic, tacts, fasciculus gracilis and fasciculus cuneatus tracts, spinocerebellar tracts. Pain conduction. Visual, auditory, gustatory, olfactor and limbic system. Motor system: pyramidal and extrapyramidal tracts. Motor nuclei. Autonomic nervous system: sympathetic and parasympathetic system. Entericnervoussystem.

1. Fondamenti di Anatomia e Fisiologia IV edizione (2019)
2. Martini, Timmons, Tallitsch,:AnatomiaUmana
3. Tortora,: AnatomiaUmana,

Students are encouraged to use an Human Anatomy Atlas

Preparation of tissues for histological analysis
Microscopy, preservation of biological structures, stainings.

Epithelial tissues
Classification of epithelia, polarity of epithelial cells, junctions, absorbent epithelia, glandular epithelia.
Connective tissues

Connective tissue proper: extracellular matrix and connective cells. The different types of connective tissue proper. Adipose tissue. Blood and hematopoietic tissues. Supportive connective: cartilage and bone.

Muscle tissue
Skeletal muscle: structure of muscle fibers, contraction mechanism, diversity of muscle fibers. Cardiac muscle: structure of cardiomyocytes and myocardial conduction mechanism. The smooth muscle.

Nervous tissue
The neuron. Glial cells. Myelinated and unmyelinated nerve fibers. General structure of the nerves.

William Bloom, Don W. Fawcett, “Elementi di istologia”, II edizione a cura diV. Cimini, CIC Edizioni Internazionali.

History of medicine: prehistoric medicine, ancient Egypt, the classical world (Greece and Rome), the Middle Ages, the modern age, the contemporary age.
History of obstetrics and gynecology.
History of birth assistance. Breastfeeding over the centuries.
History of the concept of sexuality.
History of the concept of health and disease
Main historical and ethical aspects of the relationship between health professionals and patients
Historical origins of bioethics
Birth and structuring of professional ethics
Books, objects, biological sources as tools of historical research applied to nursing.

BERNABEO R.A. Arte della Medicina, Esculapio
- COSMACINI G. L'arte lunga. Storia della medicina dall'antichità a oggi, Laterza
- LIPPI D. Storia della medicina. Per il corso di laurea triennale per ostetrici, CLUEB
- SOURNIA J.C. Storia della medicina, Edizioni Dedalo

Culture as a visible product of the Demo-Ethno-Anthropological context, the cultural mind, emotions and health, the biological role of culture, Culture in medicine, medical anthropology, anthropological elements of scientific medicine, health professions and cultural contexts of belonging, medical ethics and cultural context, examples and case studies, Basics of communication, Introduction to the THYME and SAGE models.

Donald Joralemon, Exploring Medical Anthropology, Pearson Education 2010
In alt.
J. Byron Good e S. Ferraresi, (2006), Narrare la malattia. Lo sguardo antropologico sul rapporto medico-paziente, Ed. Einaudi

DIAGNOSTIC METHODS FOR OBSTETRIC IMAGES: General criteria of diagnostic imaging. Diagnostics
with ionizing radiation, benefits, indications and contraindications for the mother and the fetus.
Ultrasound diagnosis, benefits, indications and contraindications for the mother and the fetus.
Diagnostics with Magnetic Resonance, benefits, indications and contraindications for the mother and the fetus. Radiological obstetric normal anatomy. Normal ultrasound obstetric anatomy. Normal
obstetric anatomy in MRI. Radiological obstetric pathological anatomy. Ultrasound obstetric
pathological anatomy. Obstetrical pathological anatomy in MRI.
RADIOTHERAPY METHODS IN OBSTETRICS: General criteria of radiotherapy in obstetrics. Therapy with
ionizing radiation and other radiotherapeutic sources, benefits, indications and contraindications for the
mother and the fetus.

1. Elements of diagnostic imaging by Leonardo Capaccioli and Natale Villari | 25 Jul. 2014
2. Radiology and imaging diagnostics of Di Guglielmo, Lucio, Fabrizio Calliada, and al. | 30 sets.
2012
3. Diagnostic imaging and radiotherapy. Ediz. Illustrated by Giorgio Cittadini, Giuseppe Cittadini,
et al. | 30 Jun 2015
4. Callen. Ultrasound in obstetrics and gynecology by Mary E. Norton, Leslie M. Scoutt, et al. |20 nov. 2017
5. A Practical Guide to Fetal Echocardiography: Normal and Abnormal Hearts of Abuhamad,
Alfred, M.D. and Chaoui, Rabih, M.D. | 25 nov. 2015
6. First Trimester Ultrasound Diagnostics of Fetal Abnormalities of Abuhamad, Alfred, M.D. and
Chaoui, Rabih, M.D. | Oct 25 2017
7. Ultrasonography in gynecology and obstetrics: 1 by Pastore and Cerri | 27 Jun 2012
8. Prenatal Age Medicine: Prevention, Diagnosis and Therapy of Congenital Defects and Major
Gravidic Disorders by Antonio L. Borrelli, Domenico Arduini, and al. | 13 Dec. 2014
9. Obstetric Imaging: Fetal Diagnosis and Care, by Copel MD, Joshua, D'Alton MD, Mary E., and
al. | 15 sets. 2017
10. Mammography: Guide To Interpreting, Reporting And Auditing Mammographic Images - Re,
Co.R.M. by Vincenzo Lattanzio and Giovanni Simonetti | Jan 13 2005
11. Elements of magnetic resonance by Mario Coriasco | 10 Jan 2014
12. Emergencies and urgencies in obstetrics and gynecology by Salvatore Felis, Maria Grazia
Frigo, et al. | Oct 24 2018
13.Elements of oncological radiotherapy by Mario Balducci - Francesco Cellini - Patrizia
Cornacchione - Rolando Maria D'Angelillo - Gian Carlo Mattiucci - Danilo Pasini | 5 May 2013
14.Radiotherapy techniques by Luigi Corti and Giuseppe Michelon
15.Elements of radiotherapy by Franco Milani | 31 Jul. 1998

Sociology; Beginning of sociology; Society; Groups; Social Sciences; Institutions; Social Methodology; Social changements; to understand; to observe; Social classes; personal problems and public “problems”; models of life; life as a theatre; inequalities; communication; culture; identity; mass culture; institutions; Role of the institutions.

Renato Mannheimer-Giorgio Pacifici
Europe. Sociologie di un plurale necessario. Jaca Book, 2019.

PSICOLOGIA GENERALE:
1. Neuroscience and Behaviour
2. States of consciousness
3. Learning
4. Memory
5. Thought
6. Motivation
7. Emotions

DEVELOPMENTAL PSYCHOLOGY:
1. Prenatal Development
2. Cognitive Development: Bruner, Piajet, Vygotskij
3. Moral Development: Kohlberg
4. Emotional Development: Freud
5. Attachment Theory: Winnicott and Bolbwy

COMUNICATION AND PROSOCIALITY:
1. Pragmatics of communication
2. The axioms of communication
3. Pathological communication
4. Human interaction
5. Prosocial Behaviours

• Psicologia Generale, capire la mente osservando il comportamento. N. Holt, A. Brenner, E. Sutherland, M. Vliek, M. Passer, R. smith. McGraw-Hill, 2007
• Slides given by the teacher

Introduction to the study of Pedagogy’s foundations. History of Pedagogy, teaching methods, theoretical and practical aspects of the subject.

lectures’ slides and scientific articles.

Legislation, deontology and professional organization: international category associations; legislative evolution of the midwifery profession: professional profile, deontological code, law 42/99; Autonomy, responsibility, career opportunities; professional orders and National Federation of Midwives.
Introduction to the basic concepts of midwifery care: options for place of birth, introduction to pregnancy, childbirth, postpartum and puerperium; primal health, breastfeeding and infant feeding.
Current strengths and critical points of the midwifery care.

-La disciplina ostetrica. Teoria, pratica e organizzazione della professione. AAVV. McGraw-Hill Education. 2011
-Ostetriche e Midwives. Spazi di autonomia e identità corporativa. E. Spina. Franco Angeli Edizione. 2009
-Mayes’ Midwifery. Macdonald, Johnson. Elsevier. 2017
-Primal Health: Understanding the Critical Period Between Conception and the First Birthday. M. Odent. Clairview
-Birth and Breastfeeding: Rediscovering the Needs of Women During Pregnancy and Childbirth. M. Odent. Clairview
-Didactic material (lessons in pdf, papers, etc.) delivered by the Professor
The Professor will deliver a study guide.

• Professional profile D.M. 740/94
• Code of Conduct
• Legislative evolution (Law 42/1999; Law 251/2000; Law 1/2002; Law 43/2006) - F.N.C.O.-
• The professional association
• Autonomy, responsibility and career opportunities
• Art and science of midwifery (Midwifery) at international level
• Organization of the care service: organizational roles and responsibilities
• Healthcare technologies and facilities
• Managerial skills
• Planning and personnel organization

Materials will be provided by the teacher (presentations, bibliographical insights)

Definition of health, disease and patient’s needs
-
The nursing process applied to midwifery and the care plan
-
Hygiene care
-
Patient positioning and mobilization
-
Fall prevention
-
Principles of asepsis
-
Hand washing
-
Personal Protective Equipment (PPE)
-
Measurement of vital signs
-
Health assessment
-
Collection of laboratory samples: Collection of urine sample, Collection of stool sample, Capillary
blood sampling, Venous sampling for routine and blood culture tests
-
Management of drug therapy
-
Oral drug administration
-
Subcutaneous drug administration
-
Intramuscular drug administration
-
Intravenous drug administration

Testi adottati e Bibliografia di riferimento /Book and bibliography
-
Potter & Perry (2017). Fundamentals of Nursing (9th Ed.) St. Louis, Missouri: Elsevier.
-
Slides

Introduction to the study of General Pathology
Definition of the state of health. The concept of homeostasis.
Definition of disease Aspects of the morbid process: etiology and pathogenesis, clinical manifestations, diagnosis, prognosis.
Cellular pathology: cell damage and death
Mechanism of cellular damage: free radical damage, hypoxia damage. Altered intracellular calcium homeostasis.
Reversible cell damage. Irreversible cell damage. Cell death: necrosis and apoptosis.
Cell adaptations: atrophy, hypertrophy, hyperplasia, metaplasia, dysplasia. Degeneration. Cellular aging.
Hereditary diseases
Genetic mutations. Hereditary and non-hereditary congenital diseases. Autosomal dominant and recessive diseases. Multifactorial inheritance. Sex-linked inheritance. Karyotype alterations.
Inflammation
Definition and general characteristics. Acute inflammation or angiophlogosis. The vasculoematic phenomena of inflammation: hemodynamic modifications and exudate formation. Inflammatory mediators of tissue and plasma origin. Cellular response in inflammation: inflammation cells, chemotaxis and phagocytosis; histolesivity of inflammatory cell products. Outcomes of inflammation: chronicization, healing, abscess, fibrosis. Chronic inflammaton or histophlogosis. Causes of chronic inflammation. Chronic inflammation cells and mediators. Types of chronic inflammation. Wound repair. Factors that influence healing. Systemic effects of inflammation.
Pathophysiology of thermoregulation
Temperature control. Thermodispersive and thermoconservative response. Thermoregulatory centers. Non-febrile hyperthermia. Feverish hyperthermia. Fever therapy.
Tumors
Definition. Etiology and pathogenesis. Nomenclature, classification, staging of tumors. Neoplastic invasiveness and metastasis. The carcinogenesis process. Oncogenes and tumor suppressors. Epigenetics and tumors.
Immunity and Immunopathology
Difference in the organism: mechanical chemical barriers, non-specific immunity factors, specific immunity factors.
Immune system cells. Cellular and humoral immunity. Antigens and antibodies. Stages of the specific immune response: antigen recognition, lymphocyte activation, effector phase of the immune response, elimination of the antigen. Autoimmune diseases, hypersensitivity, immunodeficiency.
Hematopoiesis
Constitution of the blood. Hematopoiesis and its regulation. Hemoglobin.
Anemias and polycythemias
Definition of anemia. Excess blood loss anemias. Insufficient erythropoiesis anemias. Megaloblastic anemias. Anemias due to impaired hematopoietic cell maturation. Hereditary defects anemias of hemoglobin synthesis: hemoglobinopathies and thalassemias. Hemolytic anemias. Polycythemia.
Leukemia
Definition. Pathophysiology. Diagnosis. Criteria for the classification of acute and chronic leukemias.
Pathophysiology of hemostasis.
The hemostatic process. Components of hemostasis and their role. Stages of the hemostatic process. The role of platelets in hemostasis and in the stages of the platelet response. The coagulation process, prothrombin time and partial thromboplastin recorded. The fibrinolytic system. The control system. Pathologies of hemostasis from vascular changes. Thrombocytopenia and thrombocytosis. Coagulation defects. Thrombosis.
Pathophysiology of the liver
Morphological aspects of the liver and biliary tract. Related aspects of the liver. Jaundices. Liver failure. Liver function tests. Main diseases of the biliary tract.
Pathophysiology of the kidney
Morphological aspects of the kidney. Glomerular ultrafiltration and its alterations. Tubukare resorption. Tubular secretion / excretion. Urine formation Kidney disease.

• “Elementi di Patologia generale e Fisiopatologia generale” – G.M.Pontieri – Piccin
• “Patologia generale” – B. Moncharmont et al. – Idelson-Gnocchi.
• “Patologia generale e fisiopatologia” – Fabio Celotti – Edises.

How to use biomarkers; biomarkers in clinical practice.
HEMATOLOGY AND HEMOSTASIS IN PREGNANCY
Composition and functions of blood. Blood count and leukocyte formula. Red blood cells: physiology and pathology (anemia, hemoglobinopathies); Platelets and leukocytes; Evaluation parameters of iron metabolism, ferritin, transferrin. Iron deficiency, vit B12 deficiency and folate deficiency. Blood groups, maternal-fetal incompatibility.
Hemostasis in pregnancy; evaluation of platelet function and of the fibrinolytic system; laboratory investigations for the definition of hypercoagulability states; diagnostic tests for poliabortivity.
FUNDAMENTALS OF IMMUNOLOGY: general characteristics of the immune system (components, functions, alterations); Immunity and inflammation.
KIDNEY FUNCTION:
Markers of kidney function: creatinine, creatinine clearance, azotemia, uric acid, electrolytes, complete urine test (chemical-physical and morphological). Laboratory tests for the diagnosis of eclampsia.
LIVER FUNCTION
Transaminases, bilirubin and others, LDH; laboratory tests for the diagnosis of intrahepatic cholestasis in pregnancy.
GLUCOSE AND LIPID METABOLISM
Indicators of glucose metabolism: glucose, glucose tolerance curves; laboratory tests for the diagnosis of gestational diabetes. Cholesterol, HDL triglycerides, LDL, apolipoproteins.

G. Federici- Medicina di laboratorio – Mc Grow Hill 2014, IV edizione
G.M. Pontieri - Elementi di Patologia e Fisiopatologia Generale - Per i corsi di Laurea in Professioni Sanitarie -Edizioni Piccin (4a Edizione, 2018).
Gronowski, Ann M. (Ed.): Handbook of Clinical Laboratory Testing During Pregnancy (testo in lingua inglese)
Joyce Le Fever Kee. Laboratory and Diagnostic Tests with Nursing implications. (10 th Edition). PEARSON Editor
Slides will be provided.

Characteristics of the main infection agents. Vital associations: commensalism, mutualism, parasitism. Associated microbial flora. Generalities on infection diseases: infectious ratio, infection and disease, endogenous infection, exogenous infections, opportunistic infections.
IMMUNOLOGY - Concept of innate immunity and acquired immunity. Role of the immune response in different infections. Survival of infection agents to immunity mechanisms. Principles of microbiological diagnostics.
BATTERIOLOGY - The bacterial cell: structure and essential functions. Gram negative and Gram positive. The bacterial spore. Cultivation of bacteria: growth and development of bacterial populations. Elements of bacterial genetics: mutations and mechanisms of genetic recombination. Principles of pathogenicity and virulence. Bacterial toxins: exotoxins and endotoxins. Mode of action of the main antibacterial drugs. Resistance to chemotherapy and antibiotics. Main bacteria responsible for human infection diseases, with particular reference to diseases of obstetrical-gynecological and maternal-fetal district (gonorrhoea, syphilis, group B streptococci infection).
VIROLOGY -Nature, methods of study and classification of viruses. Composition and architecture of the viral particle. Cultivation of viruses. Virus-cell relationship: productive infection, transforming infection. Virus-to-host relationships: acute, persistent, latent, slow infections. Pathogenic mechanisms in viral infections. Vaccines and basis of antiviral chemotherapy. Infections with the main sexually transmitted and vertically transmitted viruses: hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), human papilloma virus (HPV), herpes simplex virus (cytomegalovirus, herpes simplex virus type 1 and type 2), rubella virus and Parvovirus B19.
MYCOLOGY -Habitat and morphology of fungi (yeasts, mycelial fungi). Fungal cell structure. Infections of the urogenital district by species of the genus Candida.
PARASITOLOGY - The protozoa cell: morphology and structure. Main characteristics of Helminths and Arthropods. Protozoa of gynaecological interest: Toxoplasma gondii; Trichomonas vaginalis.

Title: The basics of Microbiology
Authors: Richard A. Harvey, Pamela C. Champe Bruce D. Fisher

The concept of risk in childbirth, low-risk pregnancy and organization of care. Risk management and basic principles of pharmacovigilance. Health promotion, preconception health, health in pregnancy and post-partum. Education for parenthood. Laws and policies on maternity and paternity. Voluntary termination of pregnancy. Anonymous birth. Pregnancy loss, stillbirth, and the sudden infant death syndrome. Obstetric violence.

-Mayes’ Midwifery. Macdonald, Johnson. Elsevier. 2017
-La disciplina ostetrica. Teoria, pratica e organizzazione della professione. AAVV. McGraw-Hill Education. 2011
-Corso di preparazione al parto. P.Maghella. Ed. Red. 2005
-Primal Health: Understanding the Critical Period Between Conception and the First Birthday. M. Odent. Clairview
-Birth and Breastfeeding: Rediscovering the Needs of Women During Pregnancy and Childbirth. M. Odent. Clairview
-Didactic material (lessons in pdf, papers, etc.) delivered by the Professor

The Professor will deliver a study guide.

• Etiology,diagnosis of vaginal and cervicalinfections;
• STI (sexuallytransmittedinfections) duringpregnancy;
• Papilloma virus;
• Cancer prevention and Pap test;
• Colposcopy;
• Hysteroscopy
• Obstetric counseling
• Invasive and non-invasive prenataldiagnosis
• Screening test
• Amniocentesis
• CVS
• Cordocentesis 

INFERMIERISTICA IN AREA MATERNO-INFANTILE”MarchioniPublisher, The mcgraw-hill companies,
“LA DISCIPLINA OSTETRICA”GuanaPublisher, The mcgraw-hill companies,
“OSTETRICA”Authors: Costantini, Calistri, Pulisher:Piccin

Physiology of pregnancy: diagnosis, main physiological modifications, description and understanding of main clinical examination recommend to evaluate wellbeing and evolution of pregnancy.

Pelvic floor: anatomy and physiology, care in pregnancy.

Cardiotocography: basics for the interpretation of the cardiotografic trace.

Pregnancy care: care pathway specific for every trimester, following a midwifery approach.

The newborn: sign of wellbeing and alarm, first and following recommend care for a physiological newborn.

Gli esami in gravidanza. Silvia Garelli, Annamaria Rossetti. 2019.

PROGRAM
• Macro and microscopic characteristics of urine and stool and their meaning.
• Identify the diagnostic tests related stool and urine and identify the technical procedures.
• Make an assessment (subjective and objective data) regarding the normal and altered characteristics of diuresis (anuria, oliguria, polyuria), urination (dysuria, nocturia, difficulty starting urination, stranguria) and urine (hematuria, bilirubinuria ,. .), to detect the presence of a bladder globe.
• Make an assessment (subjective and objective data) regarding the characteristics of the stool (fecaloma and any derivations).
• The theoretical principles that underlie the main interventions related to the urinary excretory function and the management of urinary retention, and urinary incontinence (from stress, stress, urgency, functional, reflex and regurgitation); Educational interventions to maintain the integrity of the function, for the prevention of urinary infections, assistance to the person with a bladder catheter, notes on the management of urostomies (peristomal skin hygiene and replacement of the collection bag), appropriate use of the aids for the incontinence management (diaper) and assistance to the person carrying diapers or condoms.
• Methods and scientific principles relating to extemporaneous and permanent bladder catheterization.
• The theoretical principles underlying interventions related to the faecal excretory function and the management of the risk of constipation and constipation, diarrhea and fecal incontinence. Educational interventions to maintain the integrity of the function and in the case of constipation or diarrhea (diet, fluids, intestinal gymnastics), notes on ostomy management; (hygiene of the peristomal skin and replacement of the collection bag).
• Methods and scientific principles relating to the enteroclisma (reasons for the execution, possible complications).
• Methods and scientific principles relating to the simple surgical wound dressing (possible complications of the surgical wound and indicators).
• Methods and scientific principles relating to the execution-management of a blood transfusion and blood products (responsibilities, reasons for execution, possible complications).

Saiani L, Brugnolli A. Trattato di cure infermieristiche. Napoli: Sorbona - Idelson Gnocchi; 2011.
Brunner, Suddarth. Infermieristica medico-chirurgica. Milano: Casa Editrice Ambrosiana; 2015.

APTITUDE TO RELATIONSHIP

-towards the patient
-towardsrelatives
-towards team members

APTITUDE FOR PRACTICE

-recording of vitalparameters
-assistance and treatment of the patient’sprimary needs
-administrationof therapy:
• Oral
• Intramuscular
• Infusion
-execution of venous samples
-preparation for diagnostictests
-preparation for diagnostictests or surgicalinterventions
-execution of post-surgery surgicaldressings
-guidedpostnatal execution
-support for women
use of sources information
-Written and oral submissions (medicalrecords, forms, delivery)

NURSING IN MATERNAL-CHILD AREA, Marchioni Publisher, The Mcgraw-hill companies
LA DISC OSTETRICA ,Guana Publisher, The mcgraw-hill companies
OSTETRICA, Authors: Costantini, Calistri, publisherPiccin

GENERAL PHARMACOLOGY: Basic definitions: pharmacology, drug, pharmacokinetics, pharmacodynamics, clinical pharmacology, toxicology, chemotherapy. Drug classification criteria: synthetic/semisynthetic; over the counter/prescription. Drug nomenclature: scientific name, generic name, brand name. New drug development: clinical trials and regulatory agencies (FDA and EMA). Pharmacodynamics: agonist and antagonist receptors. Dose-response curve. Pharmacodynamic parameters: potency, efficacy, affinity, EC50, ED50, TD50, LD50, therapeutic index. Different kinds of receptors: G-proteins coupled, tyrosine kinase, ion channels, intracellular receptors; second messengers. Pharmacokinetics: absorption, distribution, metabolism, excretion processes. Routes of administration, enteral and parenteral. Plasma proteins binding. Tipe I and II metabolism, CYP enzymes. Routes of excretion. Bioavailability. Pharmacokinetic and pharmacodynamic changes in pregnancy. Teratogenic drugs, mechanisms of teratogenesis; FDA risk categories in pregnancy. SPECIAL PHARMACOLOGY: steroidal anti-inflammatory drugs: mechanism of action, pharmacokinetics, pharmacodynamics, side effects. Non-steroidal anti-inflammatory drugs: classification, mechanism of action, pharmacokinetics, pharmacodynamics, side effects. Aspirin and Paracetamol. Opioid analgesics: mechanism of action, pharmacokinetics, pharmacodynamics. Tolerance, dependence and withdrawal concepts Endocrine Pharmacology: hypothalamic, pituitary, thyroid, sexual hormones. Different types of contraceptive pills.

Michelle A. Clark, Richard A. Harvey, Richard Finkel, Jose A. Rey, Karen Whalen. Pharmacology. Lippincott Williams & Wilkins, 5th edition.

Alexis L. Franks, Kimberly J. Berry, Donald B. DeFranco. Prenatal Drug Exposures and Neurodevelopmental Programming of Glucocorticoid Signaling. First published: 30 August 2019 https://doi.org/10.1111/jne.12786

Stock SJ, Norman JE. Medicines in pregnancy. F1000Res. 2019 Jun 20;8. pii: F1000 Faculty Rev-911. doi: 10.12688/f1000research.17535.1. eCollection 2019.

Ward RM, Varner MW. Principles of Pharmacokinetics in the Pregnant Woman and Fetus. Clin Perinatol. 2019 Jun;46(2):383-398. doi: 10.1016/j.clp.2019.02.014. Epub 2019 Mar 30.

Padberg S, Tissen-Diabaté T, Dathe K, Hultzsch S, Meixner K, Linsenmeier V, Meister R, Schaefer C. Safety of diclofenac use during early pregnancy: A prospective observational cohort study. Reprod Toxicol. 2018 Apr;77:122-129. doi: 10.1016/j.reprotox.2018.02.007. Epub 2018 Mar 22.

15. For each pathology
Each pathology will be introduced by base principles regarding:
1. Acquired and congenital anaemia
2. Diagnostic-therapeutic approach to chest pain
3. Acute and chronic respiratory insufficiency
4. Cardiac decompensation (heart failure)
5. Systemic arterial hypertension and the management of hypertensive emergencies
6. Acute and chronic renal impairment
7. Acute cerebrovascular pathologies
8. Diagnostic and therapeutic approach to syncope and lipothymic episodes (fainting)
9. Disorders in coagulation: thrombophilic syndromes and congenital and acquired haemorraging syndromes. THe amangement of emergencies and coagulation in pregnancy.
10. Pulmonary embolism
11. Sepsis and the managemnt of septic emergencies
12. Physiopathology of the endocrine gland: management of endocrine emergencies during pregnancy. (Typ 1 and type 2 diabetes milletus and gestational diabetes)
13. Syndromes arising from misabsorption and and chronic intestinal inflammation
14. The main auto-immune pathologies

Didactic and integrative material provided by the lecturer

Public Health and Preventive Medicine definition and goals
Determinants of health; health promotion; health education; genetic and environmental factors of disease.

Introduction to epidemiology
Demography and bio-statistical principles and analysis of more important health indicators (e.g. birth rate, mortality rate, infant mortality, etc.); absolute and relative risk. Epidemiology of infectious disease, epidemiology of chronic disease.

Primary, secondary and tertiary Prevention
Definition, timing and tools

Natural history and spectrum of infectious disease
More important infectious disease and their spread (epidemic, pandemic and cluster); direct, indirect and specific prophylaxis; infectious risk: cause, transmission, preventive measure; chemical and physical cleaning, disinfection, sterilization.

Vaccine: indications, contraindications and preventive measure
Vaccine, history and perspectives; different type of immunity; different type of immunization; vaccine schedule.

Environment and health
Climate changes, micro-climate and water; prevention of biological risk; health protection and safety of health workers

Food Hygiene and food-borne outbreaks
Human nutrition; food education; food control; Hygiene and prevention in collective catering (HACCP system);

Principles of Public Health applied to the Hospital setting
Healthcare Associated Infections (HCAI) – definition, epidemiology and prevention; Sanitization, disinfection, sterilization and disinfestation; Waste management in the hospital; Prevention and quality system aimed to ensure patient safety in the hospital (Services based on international gold standards and regulations in healthcare – JCI accreditation).

Adolescence - Menstrual cycle – Menopause
Conception - Placentation
Contraception - Emergency contraception
Prevention of sexually transmitted infectious diseases
Physiological changes in pregnancy
Twin pregnancy – The delivery
Episiotomy - Episiorrhaphy - Laceration of the birth canal
Revision of uterine cavity – Caesarean Section
Puerperious - physiopathology

• G. Bolis: Manuale di Ginecologia e Ostetricia – II Edizione 2017 – EdiSES, Napoli
• Dewhurst’s Textboo of Obstetrics and Gynaecology 7th ed. Edited by D. Keith Edmonds. EMSI Editore, Roma. Pag. 265-75, 2012.

Reality observation: clinical observation and epidemiological observation
Descriptive statistics and inferential statistics
Quantitative and qualitative variables
Absolute, relative and percentage frequency
Tables, diagrams and graphs
Statistical indices: measures of central tendency and dispersion
Central limit theorem
The normal curve (Gaussian) and its properties
Statistical inference: null hypothesis and alternative hypothesis, the value of p, the statistical association
Association and causality
Hypothesis testing and introduction to statistical significance tests
Correlation

Geoffrey R. Norman, David L. Streiner
Biostatistica. Quello che avreste volute sapere
Seconda Edizione, 2105
Casa Editrice Ambrosiana, Rozzano (MI)

Etiopathogenesis, diagnosis and surgical therapy of:
• Acute and chronic inflammation: general and surgical characteristics
• Risk factors in surgery, post-operative complications, preparation for surgery
• Escara, Ulcer, sore and gangrene.
• Burns and frostbite
• Various types of shocks
• Wounds and their healing
• Tuberculosis, carbuncle, amoebiasis
• Lymphatic system: lymphedema, lymphangitis.
• Veins and arteries; varicose veins, thrombophlebitis and phlebothrombosis, embolisms, aneurysms, chronic obstructive arteriopathies, arteriovenous fistulas.
• Anal abscesses and fistulas: Anatomy, physiology, incontinence, prolapse, hemorrhoids, anal fissure, neoplasms.
• Peritoneum: acute abdomen, peritonitis, intestinal obstruction, mechanical and paralytic ileus.

Surgical oncology: epidemiology, etiology, prevention, oncology diagnostics and antineoplastic therapies.

Title: Manual of Surgery
Authors: Pasquini Giorgio; Campa Rossella; D'Ambrosio Maurizio; Leonardo Giacomo
Publisher: McGraw-Hill
ISBN / EAN: 9788838636783
Edition: 1/2012
Title: Manual of Surgery
Authors: Pasquini Giorgio; Campa Rossella; D'Ambrosio Maurizio; Leonardo Giacomo
Publisher: McGraw-Hill
ISBN / EAN: 9788838636783
Edition: 1/2012

1. The characteristics of labour:the different stages of labour, physiology of labour.
2. Midwifery care during the first stage of labor: physiology, definition, characteristics, care settings, midwife role.
3. Midwifery care during the second stage of labor: physiology, definition, characteristics, labour and delivery phenomena, midwife role.
4. Midwifery care during the third stage of labor: physiology, definition, characteristics, management, midwife role.
5. Midwifery care in the management of perineal traumas: spontaneous lacerations, episiotomy, sutures.
6. Classification and interpretation of a cardiotocographic monitoring: characteristics of a CTG, definition of patterns, classification according to the FIGO 2015 and NICE 2017 Guidelines.
7. Setting and preparation of surgical instruments for spontaneous vaginal delivery.

Mayes' Midwifery; Editors: Sue Macdonald, Gail Johnson; Elsevier.

Planned caesarean section
Perineal techniques during the labour for reducing perineal trauma and management of the perineum after delivery
Female genital mutilation
The appropriate management of the umbilical cord
Hospital discharge of the term newborn

-NICE. Caesarean section. Clinical guideline. 2011
-SNLG. Taglio cesareo: una scelta appropriata e consapevole. 2014.
-Queensland Clinical Guidelines: Normal birth. 2018
-Aasheim V et al. Perineal techniques during the second stage of labour for reducing perineal trauma. Cochrane Library. 2018.
-WHO. Delayed umbilical cord clamping for improved maternal and infant health and nutrition outcomes. 2014
-ABM Clinical Protocol #2. Guidelines for Hospital Discharge of the Breastfeeding Term Newborn and Mother: ‘‘The Going Home Protocol,’’ Revised 2014
-Mayes’ Midwifery. Macdonald, Johnson. Elsevier. 2017
-Didactic material (lessons in pdf, papers, etc.) delivered by the Professor

The Professor will deliver a study guide.

Communication as a professionalizing practice for midwives
The management of contrattitudes in the professional relationship
Communication management in clinical cases: prenatal diagnosis (eg diagnosis of a fetus with genetic pathology), elective cesarean section, urgent cesarean section, labour induction, genital mutilation, perinatal mourning.
How to find evidence in support of clinical practice: case studies (early vs late cord clamping, request for lotus birth, case studies suggested by students).
Transcultural communication (female and male genital mutilation, nutrition during pregnancy, breastfeeding and complementary feeding).

The handouts will be provided by the teacher (presentations, bibliography)

1. Content and organizational of postnatal care: physiological changes during the postnatal period, care of women’s psychological health, the role of midwife.
2. Physical health problems and complications in the puerperium: postpartum complications and early identification of the pathological event, obstetric assistance after operative delivery, the care of woman with sign and symptoms of life-threatening conditions and those with obvious risks for increased postpartum physical morbidity.
3. Multiple pregnancy: incidence of multiple pregnancy, determination of zygosity and chorionicity, antenatal care, management of the birth.
4. Induction of labour and prolonged pregnancy: indications and contraindications and implications for induction of labour, methods of induction, evaluate the management of prolonged pregnancy.
5. Rhythmic variations of labour: recognize altered patterns of uterine action and understand how these patterns may contribute to a prolonged or precipitate labour, the use of partogram, the role of midwife in the prevention, care and management of altered patterns of uterine action.
6. Complications related to the third stage of labour: postpartum haemorrhage, recognize risk factors, signs and symptoms, the role of midwife in emergency management, the importance of teamwork.
ADDITIONAL:
Preterm labour: identify the risk factors for preterm labour, recommended drugs for preter labour (tocolytics), implications of preterm labour and preterm birth for the baby and the family.
Thermoregulation: the mechanism oh heat loss , knowledge of neutral thermal environment for the newborn, identification of signs and symptoms of cold stress, the role of the midwife.
Resuscitation of the newborn: the knowledge of the algorithm, the role of midwife.

Mayes' Midwifery; Editors: Sue Macdonald, Gail Johnson; Elsevier.

• Personalized care of the patient to achieve the desiredpatientoutcome
• Safe and effective care of the patientundergoing analgesia/anaesthesia/sedation
• Selectinginstruments and equipment appropriate for the surgery and assist the surgeon
• Performingongoingpatientassessment in everyphases of the perioperativeperiod, formulating nursing diagnosis andimplementingevidencebasedprocedures
• identify the liability of the midwife in the perioperative setting in accordance with the professional standards of practice and behaviour
• developingcommunication and interpersonal skills
• Enforcing policies thatcontribute to patientsafety

• eather Nixon, MD,LisaLeffert, MD;Anesthesia for cesarean delivery; Aug 20H19
• Goodman, Cynthia Spry; Essentials of Perioperative Nursing; Jones & Bartlett Publishers, 2016
• Ragusa, Crescini; Urgenze ed Emergenze in Sala Parto;Piccin;October 2016
• Nell Tharpe, Caity Byrne; The MidwifeasSurgical First Assistant; 2015

Physiology of breastfeeding and lactation
Management of complex clinical cases in breastfeeding
Development of the human microbiome, epigenetics and neurodevelopment
Active fatherhood and the promotion of the early child development
Prevention of male violence against women and children
Nurturing care: from theory to practice
Transcultural midwifery care in breastfeeding
Midwifery care in humanitarian emergencies and natural disasters

The handouts will be provided by the teacher (presentations, bibliography)

Why breastfeeding is important. Positioning a baby at the breast. Observing and assessing a breastfeed.
Specific cases: refusal to breastfeed, "Not enough milk", crying.
Breast: breast characteristics and problems.
Induction of labour (IOL): relevant topics, elements that influence the success and failure of IOL, induction failure, indications for IOL, methods for IOL, maternal-fetal surveillance during IOL.

“Salute primale e allattamento”. Manuale aggiornato e basato sul modello formativo del corso 40 ore OMS-UNICEF.
Materiale di studio (lezioni in pdf, etc.) consegnato dal docente.
Mayes' Midwifery; Editors: Sue Macdonald, Gail Johnson; Elsevier.

Local breastfeeding situation. How breastfeeding works.
Specific cases: low-birth-weight and sick babies, maternal diseases.
Breast: expressing breastmilk increasing breastmilk and relactation.
Women's nutrition, health and fertility. Women and work.
Primal health, UNICEF Baby friendly Initiatives and the marketing of breast-milk substitutes.
Counselling practice: listening and learning, building confidence and giving support, taking a breastfeeding history, sustaining breastfeeding.

-“Salute primale e allattamento”. Manuale aggiornato e basato sul modello formativo del corso 40 ore OMS-UNICEF
-Primal Health: Understanding the Critical Period Between Conception and the First Birthday. M. Odent. Clairview
-Birth and Breastfeeding: Rediscovering the Needs of Women During Pregnancy and Childbirth. M. Odent. Clairview
-Didactic material (lessons in pdf, papers, etc.) delivered by the Professor
The Professor will deliver a study guide.

• Carcinogenesispathophysiology
• Epidemiology, Etiology,diagnosis, and staging of gynecologicalcancer
• Papilloma virus;
• Cancer prevention and Pap test;
• Ovariancancer
• Breastcancer
• Endometrialcancer
• Cervixcancer
• BRCA1 and BRCA2 and geneticcounseling

“LINEE GUIDA AIOM “ 2019
“”MEDICINA ONCOLOGICA” Gianni Bonadonna , Gioacchino Robustelli Della Cuna , Pinuccia Valagussa

Congenital malformations (head, neck, thorax, abdomen, genital and urinary tract); malformations and obstructions of the upper airways; esophageal atresia; bowel obstruction baby girl; newborn abdominal masses; acute scrotum.

Elementi di Chirurgia Pediatrica, Ferdinando Cataliotti, edito dalla Piccin
Chirurgia Pediatrica, Alberto Ottolenghi, edizioni Calderini

The program includes the following topics:

• General principles
• Physiology and pathophysiology of the hypothalamic-pituitary- endocrine glandaxis.
• Physiology and pathophysiology of the endocrine pancreas.
• Diabetes Mellitus: classification, pathogenesis, clinical manifestation and medical treatment.
• Obesity and Metabolic Syndrome.
• Female and male gonad and main diseases
• Physiology and pathophysiology of calcium-phosphorus metabolism of the parathyroid glands.
• Osteoporosis and endocrine diseases of the bone.
• Physiology of the thyroid gland and thyroid diseases (thyroiditis, hypothyroidism, hyperthyroidism, thyroid neoplasia).

• Richard David G. Leslie, Shern L. Chew, “Clinical Endocrinology and Diabetes”, Editore Churchill Livingstone, 2005
• David G. Gardner, Dolores Shoback, “Greenspan’s Basic and Clinical Endocrinology”, 10th Edition,

• Anatomy of the female and male reproductive system.
• Human reproductive physiology: The menstrual cycle, the hormones of the hypothalamus-pituitary axis, ovarian steroidogenesis.Spermatogenesis. Epidemiology ofinfertility.
• Endocrine disorders in infertile woman: primary and secondary amenorrhea, • polycystic ovarian syndrome. Pituitary and ovarian hormone profile.
• Gynecological causes of female infertility, endometriosis, classification of congenital uterine malformations. Genetic causes of male and female infertility.
• Instrumental diagnosis: ultrasound, monitoring of ovulation, hysterosalpingography, hysteroscopy and laparoscopy. Therapeutic approaches in infertile couple. Use of food supplements and hormones. The different assisted reproduction techniques both homologous and heterologous. Italian legislation on ART.

Linda j. Effner.Reproductive system at aglance 4th edition.Blackwell Publishers, 2014

Physiopathology of implantation and earlypregnancy.

Miscarriage: etiology, clinicalforms, diagnosis, principles of treatment.

Ectopicpregnancy: etiology, pathophysiology, clinicalpresentation, diagnosis,principles of treatment.

Hypertensivedisorders of pregnancy (pregnancy-inducedhypertension, preeclampsia, eclampsia): etiology, pathogeneticmechnisms, diagnosis, principles of treatment.

Diabetes in pregnancy: etiology, pathogeneticmechnisms, diagnosis, principles of treatment.

Abruptio placenta and placenta previa: etiology, pathogeneticmechnisms, diagnosis, principles of treatment.
Pretermlabor: Etiology, pathogeneticmechnisms, diagnosis, principles of treatment.

• G. Bolis: Manuale di Ginecologia e Ostetricia – II Edizione 2017 – EdiSES, Napoli

• Dewhurst ‘s Textbook of Obstetrics and Gynaecology 7th ed. Edited by D. Keith Edmonds. EMSI Editore, Roma. Pag. 265-75, 2012.

Preterm birth and preterm infant: clinical course and care plan.
Neonatal hypoglycemia: prevention, signs, diagnosis and treatment.
Group B streptococcal infection in pregnancy: prevention, diagnosis, treatment and neonatal outcomes.
Meconium aspiration syndrome and main postnatal disorders after birth.

-Mayes’ Midwifery. Macdonald, Johnson. Elsevier. 2017
-Didactic material (lessons in pdf, papers, etc.) delivered by the Professor

The Professor will deliver a study guide.

• Personalized care of the patient to achieve the desired patient outcome
• Safe and effective care of the patient under going analgesia/anaesthesia/sedation
• Selecting instruments and equipment appropriate for the surgery and assist the surgeon
• Performingongoingpatientassessment in everyphases of the perioperativeperiod, formulating nursing diagnosis andimplementingevidencebasedprocedures
• identify the liability of the midwife in the perioperative setting in accordance with the professional standards of practice and behaviour
• developingcommunication and interpersonal skills
• Enforcing policies thatcontribute to patientsafety
• PerformingGynecological and Obstetric’sEmergecies management in theatre

• Heather Nixon, MD,LisaLeffert, MD;Anesthesia for cesarean delivery; Aug 2019
• Goodman, Cynthia Spry; Essentials of Perioperative Nursing; Jones & Bartlett Publishers, 2016
• Ragusa, Crescini; Urgenze ed Emergenze in Sala Parto;Piccin;October 2016
• Nell Tharpe, Caity Byrne; The MidwifeasSurgical First Assistant; 2015

Genomic Imprinting
Mitochondrial inheritance: mitochondrial DNA, pattern of inheritance
Multifactorial inheritance: polimorphisms, susceptibility genes, gene-environment interaction, association studies
Pharmacogenomics and Personalised Medicine
Genetic tests and Counselling. Prenatal and postnatal testing
Diagnosis of genetic diseases: some examples
Epigenetics and nutrigenetics. Outlines

Lectures in pdf format will be provided to students.
Recommended books:
“Medical Genetics”,

4.1 General principles of psychology
What is psychology? History of psychology
Main psychological perspeectives social psychology
4.2 Neuroscientific foundation of psychology
The brain: principles of anatomy and of physiology.
Functions, emotions and behaviors
4.3 Higher mental functions
Thinking
Language
Intelligence
Consciousnes
Learning
Memory
4.4 Lifespan development
Prenatal psychology
Developmental psychology
Childhood Psychology
Adulthood Psychology
Death psychology
4.5 Personality Theories
4.6 Psychopathological disorders
Anxiety disorders
Mood disorders
Psychotic disorders

General Psychology: Briefer Course 
Editore: Kessinger Pub Co 
Lingua: Inglese

Importance of infections during pregnancy
Infections of the fetus: pathogenesis, efficiency of transmission of microorganism from mother to fetus, diagnosis of infection in the pregnant woman, diagnosis of infection in the newborninfant
Obstetric factors associated with infections in the fetus and newborn infant
Bacterial infections in pregnancy
Viral infections
Protozoan and fungal infections in pregnancy
PROM and infections
Neonatal sepsis
Benefit and risks of human milk
Clinical pharmacology of anti-infective drugs in pregnancy
Vaccinations in pregnancy

Studymaterial (lessons in pdf ,articles, etc.) delivered by the teacher.
Infezioni in gravidanza di Nicola Rizzo e Gianluigi Pilu2012

• Communication skills towards the patient
• Towardsrelatives
• Towards members of the team

• Recording of vitalsigns
• Administration of therapy


• Changing of the newborn
• Medication of the umbilicalcord
• Administration of fluids per os to the newborn
• Havingfollowed the obstetricvisits
• Execution of an ECG
• Breastfeeding support
• Execution of vaginal and cervicalswabs
• Hysteroscopies
• Colposcopies
• Execution of maternal and neonatalmedicatins
• Observation of ost-gin ultrasounds
• Observation and execution of Pap-test
• Observation and application of CTG
• Participation in accompanyingcoursesatbirth
• Correctlyinformingabout sex education
• Preaparation for diagnostictests
• Preparation for diagnostictests or surgical operations
• Execution of post-operative surgicaldressings
• Guided post-operative execution
• Support for women
• Use sources of information and guidelines and protocols
• Written and oral transmissions (medicalrecord, forms, certificates)

NURSING IN MATERNAL-CHILDRIN AREA, Marchioni Publisher, the mcgraw-hill companies
THE OBSTESTRIC DISCIPLINE, GuanaPublisher , the mcgraw-hill companies
OBSTETRICA Authors: Costantini, Calistri, Piccic Publisher

General Scientific English Glossary is the lexical path for getting the course aims, with a focus on
Gynaecology and Obtetrics topics (English for Healthcare Providers). Students are requested to
comment and share videos and documents describing laboratory activities in different settings
and worldwide countries, having practice with different scientific idioms and grammar issues,
noting different phonetic ways in written and spoken English.
English At Work Elements study as well is important to deal with the ordinary needs in the
scientific field routines (Basic Business English)
Grammar Topics are finally important to update the student’s previous knowledge and practice (
Phrasal verbs, English idioms, holding a conversation, a job interview,etc.)

“English on duty” ( M.J.Teriaca, Scienza Medica Ed.)
“English for Nurses and Healthcare Providers” ( A.Destrebecq, Ambrosiana Ed.)
“Oxford English for careers ,Student book” (T.Grice, J.Greenan, O.U.P.)
“Oxford English Grammar Course” (M.Swann, O.U.P.)
“Advanced Grammar in use” (M.Hewings, Cambridge)
Students will be provided with additional reading material by the Instructor if required.