The course will deal with the general principles of pharmacology that apply to all drugs and therefore the classes of drugs directly and indirectly correlated with radiological practice. In particular, in the general part, students will have to learn the principles of pharmacokinetics, pharmacodynamics, pharmacogenetics that apply to all classes of drugs, including radiopharmaceuticals and contrast media. In the special part, particular emphasis will be placed on radiopharmaceuticals (used for both diagnostic and therapeutic purposes), contrast media and drugs used for the control of inflammation, pain, anxious states, the main neurological disorders, anticancer drugs, monoclonal antibodies, antibacterial chemotherapy and drugs used in the respiratory emergency. After completing the course, students should know and understand the mechanism of action, pharmacokinetics, side effects, toxicological aspects, contraindications of the main radionuclides used in SPECT and PET nuclear medicine and must be able to control, when perform an instrumental examination using a radiopharmaceutical, the patient's physical safety.