Medical oncology and blood diseases
(objectives)
Students will need to know the predisposing conditions and the clinical characteristics of the various neoplastic diseases, prognostic and predictive factors related both to the neoplasm and to the patient, hematopoietic and lymphoid system and its physiopathological disorders. Moreover, students are asked to know the main laboratory analysis systems, the cellular isolation methods, standard molecular biology techniques commonly used in the oncohematological, how to store hematological samples, how to apply diagnostic technologies required for diagnostic and prognostic assessment of hematological patients. Students will have to possess the notions and principles relating to Diagnostic Imaging (including interventional radiology) to integrate the knowledge of the professional profile with those relating to diagnostic imaging technologies.These objectives will be achieved through lectures aimed at improving students’ learning capabilities in order to achieve useful skills for collaboration with multidisciplinary teams. These objectives will be verified through in itinere and final tests.
|
Code
|
90342 |
Language
|
ITA |
Type of certificate
|
Profit certificate
|
Module: Medical oncology
(objectives)
The essential objectives of the integrated course of "MEDICAL ONCOLOGY AND BLOOD DISEASES" are knowledge of the predisposing conditions and clinical characteristics of the solid and haematological neoplastic disorders, as well as, the prognostic and predictive factors of response according to the specific characteristics of both neoplasm and patient, as such as, the understanding of the haematolymphopoietic system and the pathophysiological alterations related to it, as well as the biological mechanisms mediated by cytokines and adhesion molecules that regulate innate and mediated immunity. The aim of the integrated course will also be to learn the principles of primary, secondary prevention and chemo-prevention in the field of solid and haematological tumors. Emphasis will be placed on the role of tumor markers and molecules that can help to well define the diagnostic assessment, as well as the importance of malnutrition and the role of microbiology related to the intestinal microbiota. It is also required to learn the main laboratory analysis systems, cell isolation and molecular biology methods, biological sample preservation techniques and the application of biotechnology in the diagnosis and prognostic evaluation of the hematological patient. Students will have to possess the notions and principles relating to Diagnostic Imaging (including interventional radiology) to integrate the knowledge of the professional profile with those relating to diagnostic imaging technologies. These objectives will be achieved through lectures aimed at improving students’ learning capabilities in order to achieve useful skills for collaboration with multidisciplinary teams. These objectives will be verified through intermediate and final evaluation tests.
|
Language
|
ITA |
Type of certificate
|
Profit certificate
|
Credits
|
5
|
Scientific Disciplinary Sector Code
|
MED/06
|
Contact Hours
|
50
|
Type of Activity
|
Core compulsory activities
|
Teacher
|
Giorgetti Gian Marco
(syllabus)
- Role of the Microbiota in the pathogenesis of cancer - Nutritional aspects in cancer patients - The molecular basis of carcinogenesis - Innate and mediated immunity in cancer - The malignant tumor phenotype - Genetic alterations underlying tumors - Causes of tumors - Prevention and cancer - Definition and classification criteria - General characteristics of benign tumors - General characteristics of malignant tumors - Differentiation, growth rate and invasion-metastasis - Inflammation and cancer - Hypertrophy - hyperplasia - atrophy - metaplasia - dysplasia - Oncogenes - precancerous conditions - Esophageal tumors (clinical picture - diagnosis - therapy - staging) - Gastric tumors (clinical picture - diagnosis - therapy - staging) - Complications of gastrectomy (dumping syndrome - impaired digestion of fat) - Colorectal tumors - Hereditary forms - Clinical picture staging therapy - Exocrine pancreas tumor (classification - diagnosis - therapy - staging) - Endocrine pancreas tumor (classification - diagnosis - therapy) - Lung tumors (classification diagnosis therapy on topics covered) - Urinary tract tumors (classification diagnosis therapy) - Lymphomas (classification diagnosis therapy) - Liver and gallbladder tumors (classification diagnosis therapy)
(reference books)
Chmielowski B., Territo M.C. Manual of Clinical Oncology. Ed: Lippincott Williams and Wilkins. ISBN 9781496349576 Bianco, De Placido, Tortora & Conte, Core curriculum di Oncologia Clinica 2/ed Mc Graw Hill Educa-tion (Italy) Harrison, Principi di Medicina Interna, Ed CEA 2016- capitoli dedicati alle malattie neoplastiche The slides and the articles shown during the course will be made available to the student and will constitute the reading material for the course of Medical Oncology
|
Dates of beginning and end of teaching activities
|
From to |
Delivery mode
|
Traditional
|
Attendance
|
not mandatory
|
Evaluation methods
|
Written test
Oral exam
|
Teacher
|
Cecere Fabiana Letizia
(syllabus)
Epidemiology - Carcinogenesis - Risk factors - Spreading - Initial approach - Prognosis - Staging - Therapy - Lung neoplasms - Laboratory abnormalities - Tumor markers
(reference books)
Chmielowski B., Territo M.C. Manual of Clinical Oncology. Ed: Lippincott Williams and Wilkins. ISBN 9781496349576 Bianco, De Placido, Tortora & Conte, Core curriculum di Oncologia Clinica 2/ed Mc Graw Hill Educa-tion (Italy) Harrison, Principi di Medicina Interna, Ed CEA 2016- capitoli dedicati alle malattie neoplastiche The slides and the articles shown during the course will be made available to the student and will constitute the reading material for the course of Medical Oncology
|
Dates of beginning and end of teaching activities
|
From to |
Delivery mode
|
Traditional
|
Attendance
|
not mandatory
|
Evaluation methods
|
Written test
Oral exam
|
Teacher
|
Grassi Giovanni Battista
(syllabus)
- General concepts of oncology - Prevention in oncology - Risk factors - Breast neoplasms: anatomy, causes, symptoms, diagnosis, prognosis, prevention, therapy - Thyroid neoplasms: anatomy, causes, symptoms, diagnosis, prognosis, prevention, therapy - Gastrointestinal tract neoplasms (stomach and colorectal): anatomy, causes, symptoms, diagnosis, prognosis, prevention, therapy - Urogenital neoplasms: anatomy, causes, symptoms, diagnosis, prognosis, prevention, therapy
(reference books)
Chmielowski B., Territo M.C. Manual of Clinical Oncology. Ed: Lippincott Williams and Wilkins. ISBN 9781496349576 Bianco, De Placido, Tortora & Conte, Core curriculum di Oncologia Clinica 2/ed Mc Graw Hill Educa-tion (Italy) Harrison, Principi di Medicina Interna, Ed CEA 2016- capitoli dedicati alle malattie neoplastiche The slides and the articles shown during the course will be made available to the student and will constitute the reading material for the course of Medical Oncology
|
Dates of beginning and end of teaching activities
|
From to |
Delivery mode
|
Traditional
|
Attendance
|
not mandatory
|
Evaluation methods
|
Written test
Oral exam
|
|
|
Module: Blood diseased, oncohematology
(objectives)
The essential objectives of the integrated course of "MEDICAL ONCOLOGY AND BLOOD DISEASES" are knowledge of the predisposing conditions and clinical characteristics of the solid and haematological neoplastic disorders, as well as, the prognostic and predictive factors of response according to the specific characteristics of both neoplasm and patient, as such as, the understanding of the haematolymphopoietic system and the pathophysiological alterations related to it, as well as the biological mechanisms mediated by cytokines and adhesion molecules that regulate innate and mediated immunity. The aim of the integrated course will also be to learn the principles of primary, secondary prevention and chemo-prevention in the field of solid and haematological tumors. Emphasis will be placed on the role of tumor markers and molecules that can help to well define the diagnostic assessment, as well as the importance of malnutrition and the role of microbiology related to the intestinal microbiota. It is also required to learn the main laboratory analysis systems, cell isolation and molecular biology methods, biological sample preservation techniques and the application of biotechnology in the diagnosis and prognostic evaluation of the hematological patient. Students will have to possess the notions and principles relating to Diagnostic Imaging (including interventional radiology) to integrate the knowledge of the professional profile with those relating to diagnostic imaging technologies. These objectives will be achieved through lectures aimed at improving students’ learning capabilities in order to achieve useful skills for collaboration with multidisciplinary teams. These objectives will be verified through intermediate and final evaluation tests.
|
Language
|
ITA |
Type of certificate
|
Profit certificate
|
Credits
|
5
|
Scientific Disciplinary Sector Code
|
MED/15
|
Contact Hours
|
50
|
Type of Activity
|
Core compulsory activities
|
Teacher
|
Fabiani Emiliano
(syllabus)
Bone marrow nice - Haematopoietic stem cell - Haematopoiesis - Anemia - Clonal haematopoiesis - Myelodysplastic syndrome - Acute myeloid leukaemia - Acute lymphoblastic leukaemia - Myeloproliferative disorders - Chronic myeloid leukaemia - Lymphoma - Peripheral blood sampling and bone marrow aspirate - Haematological cell culture technics - Peripheral blood and bone marrow smear - Isolation of mono and polymorphonuclear cells - Stem cell isolation: culture, amplification and cryopreservation - Cytofluorimetry - Karyotype aberrations: conventional and molecular cytogenetics (FISH) - Diagnostic and prognostic role of molecular biology in oncohaematology - Extraction and storage of nucleic acids (DNA and RNA) for haematological tests - Basic techniques in molecular biology: nucleic acids amplification - Qualitative analysis (PCR and RT-PCR), diagnostic approach - Minimal residual disease - Qualitative analysis (PCR and RT-PCR), prognostic approach - Gene mutations - Sanger sequencing - New generation sequencing and personalized medicine: applications, progress, costs and benefits
(reference books)
Hematology: pathophysiology, diagnosis and treatment. Sante Tura, Michele Cavo e Pier Luigi Zinzani. Casa editrice Esculapio. Corso di Malattie del Sangue e degli Organi Emolinfopoietici. Sante Tura, Michele Cavo e Pier Luigi Zinzani. Società editrice Esculapio. The slides shown during the course will be made available to the s
|
Dates of beginning and end of teaching activities
|
From to |
Delivery mode
|
Traditional
|
Attendance
|
not mandatory
|
Evaluation methods
|
Written test
Oral exam
|
|
|
Module: Diagnostic imaging
(objectives)
The essential objectives of the integrated course of "MEDICAL ONCOLOGY AND BLOOD DISEASES" are knowledge of the predisposing conditions and clinical characteristics of the solid and haematological neoplastic disorders, as well as, the prognostic and predictive factors of response according to the specific characteristics of both neoplasm and patient, as such as, the understanding of the haematolymphopoietic system and the pathophysiological alterations related to it, as well as the biological mechanisms mediated by cytokines and adhesion molecules that regulate innate and mediated immunity. The aim of the integrated course will also be to learn the principles of primary, secondary prevention and chemo-prevention in the field of solid and haematological tumors. Emphasis will be placed on the role of tumor markers and molecules that can help to well define the diagnostic assessment, as well as the importance of malnutrition and the role of microbiology related to the intestinal microbiota. It is also required to learn the main laboratory analysis systems, cell isolation and molecular biology methods, biological sample preservation techniques and the application of biotechnology in the diagnosis and prognostic evaluation of the hematological patient. Students will have to possess the notions and principles relating to Diagnostic Imaging (including interventional radiology) to integrate the knowledge of the professional profile with those relating to diagnostic imaging technologies. These objectives will be achieved through lectures aimed at improving students’ learning capabilities in order to achieve useful skills for collaboration with multidisciplinary teams. These objectives will be verified through intermediate and final evaluation tests.
|
Language
|
ITA |
Type of certificate
|
Profit certificate
|
Credits
|
1
|
Scientific Disciplinary Sector Code
|
MED/36
|
Contact Hours
|
10
|
Type of Activity
|
Core compulsory activities
|
Teacher
|
Midiri Federico
(syllabus)
- Physics of ionizing and non-ionizing radiation; - Radiobiology: mechanisms of action of radiations on living matter (DNA effects and repair mechanisms, cell damage, radiosensitivity and effect on cellular cycle, repair and repopulation, response modifiers, oxygen effect); - Contrast media: classification and characteristics; clinical applications; adverse reactions and management; - Functioning principles of diagnostic devices using ionizing radiations (conventional radiology and Computed Tomography); - Ultrasound principles: physics and clinical applications; - Physics of Magnetic Resonance; - Vascular and interventional radiology equipment; - Principles of nuclear medicine imaging; - Notes on the main radiotherapy equipment; - Main applications of diagnostic imaging with particular reference to oncology and blood diseases;
(reference books)
Diagnostica per immagini e radioterapia di Cittadini Giorgio - Cittadini Giuseppe - Sardanelli Francesco Editore: EDRA – MASSON Edizione: VII 2015 Pagine: 1150 ISBN: 8821440001 ISBN-13: 9788821440007 Data pubblicazione: 2015 The slides and the articles shown during the course will be made available to the student and will constitute the reading material for the course of Diagnostic Imaging
|
Dates of beginning and end of teaching activities
|
From to |
Delivery mode
|
Traditional
|
Attendance
|
not mandatory
|
Evaluation methods
|
Written test
Oral exam
|
|
|
|