| Clinical biochemistry and pharmaceuticals toxicology
(objectives)
The course aims to acquire the fundamental principles of pharmacokinetics, pharmacodynamics, toxicology, and pharmaceutical galenics, which form the basis for conducting biochemical and pharmacogenetic tests in diagnostic and research laboratories, as well as the theoretical foundations for the preparation of galenic drugs. Students should be familiar with the scientific rigor and methodological approach underlying the development of new drugs. They should also learn the fundamental aspects related to the therapeutic use of the most frequently used drug classes. These objectives will be achieved through lectures, seminars, and interactive educational activities designed to facilitate learning and enhance the ability to address and resolve key issues in the pharmaceutical, toxicological, and pharmaceutical galenic industries.
The educational objectives of the module of Special Clinical Biochemistry are aimed at acquiring knowledge of the main methodologies used in clinical biochemistry; understanding the significance of alterations in biochemical-clinical relevant profiles.
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Code
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90334 |
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Language
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ITA |
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Type of certificate
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Profit certificate
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| Module: Special clinical biochemistry
(objectives)
The course aims to acquire the fundamental principles of pharmacokinetics, pharmacodynamics, toxicology, and pharmaceutical galenics, which form the basis for conducting biochemical and pharmacogenetic tests in diagnostic and research laboratories, as well as the theoretical foundations for the preparation of galenic drugs. Students should be familiar with the scientific rigor and methodological approach underlying the development of new drugs. They should also learn the fundamental aspects related to the therapeutic use of the most frequently used drug classes. These objectives will be achieved through lectures, seminars, and interactive educational activities designed to facilitate learning and enhance the ability to address and resolve key issues in the pharmaceutical, toxicological, and pharmaceutical galenic industries.
The educational objectives of the module of Special Clinical Biochemistry are aimed at acquiring knowledge of the main methodologies used in clinical biochemistry; understanding the significance of alterations in biochemical-clinical relevant profiles.
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Language
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ITA |
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Type of certificate
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Profit certificate
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Credits
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2
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Scientific Disciplinary Sector Code
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BIO/12
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Contact Hours
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20
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Type of Activity
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Core compulsory activities
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Teacher
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Montagna Costanza
(syllabus)
From biological sample collection to reporting
Pre-pre-analytical phase, pre-analytical phase, analytical phase, post-analytical phase, interpretation of results.
Analytical groupings
Blood, urine, feces, CSF, hair, and saliva.
Profiles of biochemical-clinical significance
Glucose profile, protein profile, lipid profile, profile. vitamin profile.
(reference books)
Biochimica clinica essenziale, dal laboratorio ai quadri di patologia clinica. Elisabetta Albi Tommaso Beccari Samuela Cataldi. Zanichelli 2019.
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Dates of beginning and end of teaching activities
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From to |
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Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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| Module: Pharmaceutical toxicology and galenic pharmacology
(objectives)
The course aims to acquire the fundamental principles of pharmacokinetics, pharmacodynamics, toxicology, and pharmaceutical galenics, which form the basis for conducting biochemical and pharmacogenetic tests in diagnostic and research laboratories, as well as the theoretical foundations for the preparation of galenic drugs. Students should be familiar with the scientific rigor and methodological approach underlying the development of new drugs. They should also learn the fundamental aspects related to the therapeutic use of the most frequently used drug classes. These objectives will be achieved through lectures, seminars, and interactive educational activities designed to facilitate learning and enhance the ability to address and resolve key issues in the pharmaceutical, toxicological, and pharmaceutical galenic industries.
The educational objectives of the module of Special Clinical Biochemistry are aimed at acquiring knowledge of the main methodologies used in clinical biochemistry; understanding the significance of alterations in biochemical-clinical relevant profiles.
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Language
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ITA |
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Type of certificate
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Profit certificate
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Credits
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3
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Scientific Disciplinary Sector Code
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BIO/14
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Contact Hours
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30
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Type of Activity
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Basic compulsory activities
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Teacher
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Apolloni Savina
(syllabus)
PHARMACOTOXICOLOGY AND PHARMACEUTICAL GALENICS
General principles of pharmacology: drug definition, drug classification, and nomenclature; desired and undesired effects of drugs.
General principles of pharmacokinetics: routes of administration, absorption, distribution, metabolism, elimination of drugs.
Pharmacogenomics: individual variability and drug response, variations in target proteins, variations in drug-metabolizing enzymes.
General principles of toxicology; toxicokinetic; mechanisms of intoxication and detoxification; main sources of toxicity; toxic effects of drugs.
General principles of pharmacodynamics: receptors and mechanisms of drug action.
Development of new drugs: general principles of in vitro pharmacological sensitivity tests, preclinical studies, experimental models of diseases, and clinical trials.
Pharmacology of the Autonomic Nervous System (parasympathomimetics and cholinergic antagonists; sympathomimetics and adrenergic antagonists).
Pharmacology of the Central Nervous System (anxiolytics, antipsychotics, antidepressants, drugs for neurodegenerative diseases).
Special Pharmacology; general characteristics of the following drug classes: anti-inflammatories, antihistamines, opioid analgesics, antimicrobial agents, antitumor drugs, brief overview of gastrointestinal, pulmonary, and cardiovascular pharmacology.
Principles of pharmaceutical galenics, techniques for galenic and pharmaceutical preparations, auxiliary substances in galenic preparations: solvents, excipients, preservatives. Techniques applied in UFA laboratories and CAR-T therapies.
(reference books)
• Di Giulio et al. "Farmacologia generale e speciale per le lauree sanitarie." Piccin, second edition
• Amico Roxas et al. "Compendio di farmacologia generale e speciale, second edition." EDRA 2021
• Clementi F., Fumagalli G. "FARMACOLOGIA GENERALE E MOLECOLARE 5a edizione." EDRA 2018.
• C. Colombo, F. Alhaique, C. Caramella, B. Conti, A. Gazzaniga, E. Vidale. "Principi di Tecnologia Farmaceutica." Zanichelli 2015.
• Other materials and scientific articles indicated by the teacher.
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Dates of beginning and end of teaching activities
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From to |
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Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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