The learning objectives of the Course in GENERAL PATHOLOGY are to enable the student to understand the molecular mechanisms of cell damage, the response of the cell and the organism to damage, the biology and molecular basis of the neoplastic transformation, and the causes of human diseases, interpreting the fundamental pathogenetic mechanisms. In addition, we will also introduce basic principles of pathophysiology of the major systems as circulation, hepatobiliary and metabolism. Objectives of the course are also the understanding of basic laboratory techniques; cellular isolation methods; standard molecular biology techniques; correct and efficient storage of biological samples; how to apply diagnostic technologies needed to help the assessment of the diagnosis and prognosis of patient.