| Pharmacology and neuropsychiatric sciences
(objectives)
Pharmacology
After completing the course, students should be able to:
- understand and describe the basic principles of pharmacology, in particular notions of pharmacokinetics and pharmacodynamics, and the experimental phases for the development of new drugs. Students will also know the main pharmacological strategies used for anticancer and antibacterial therapies, for the treatment of inflammation, pain, cardiovascular, respiratory and neurological diseases.
- describe the mechanisms of damage subtending the most common diseases affecting the central and the peripheral nervous system and their clinical and instrumental diagnostic process. Particular attention must be paid to the description of the neurobiological mechanisms favoring the recovery from acute and chronic neuronal damage as well as the mechanisms that support plasticity, including functional properties of circuitries.
- acquire scientific and medico-clinical knowledge necessary to identify, define, frame and possibly classify the neurosurgical pathologies most commonly encountered in daily clinical practice
- understand the pathophysiological mechanisms that led to the "neurological deficit", knowing how to trace its origin and how to define its anatomical-clinical features.
- know the the fundamentals of psychopathology and the history of psychiatry.
- know the basic mechanisms of of pathophysiology, the clinic and the treatment of the main psychiatric disorders.
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Code
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90310 |
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Language
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ENG |
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Type of certificate
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Profit certificate
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| Module: Neurology
(objectives)
Pharmacology
After completing the course, students should be able to:
- understand and describe the basic principles of pharmacology, in particular notions of pharmacokinetics and pharmacodynamics, and the experimental phases for the development of new drugs. Students will also know the main pharmacological strategies used for anticancer and antibacterial therapies, for the treatment of inflammation, pain, cardiovascular, respiratory and neurological diseases.
- describe the mechanisms of damage subtending the most common diseases affecting the central and the peripheral nervous system and their clinical and instrumental diagnostic process. Particular attention must be paid to the description of the neurobiological mechanisms favoring the recovery from acute and chronic neuronal damage as well as the mechanisms that support plasticity, including functional properties of circuitries.
- acquire scientific and medico-clinical knowledge necessary to identify, define, frame and possibly classify the neurosurgical pathologies most commonly encountered in daily clinical practice
- understand the pathophysiological mechanisms that led to the "neurological deficit", knowing how to trace its origin and how to define its anatomical-clinical features.
- know the the fundamentals of psychopathology and the history of psychiatry.
- know the basic mechanisms of of pathophysiology, the clinic and the treatment of the main psychiatric disorders.
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Language
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ENG |
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Type of certificate
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Profit certificate
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Credits
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2
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Scientific Disciplinary Sector Code
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MED/26
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Contact Hours
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20
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Type of Activity
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Core compulsory activities
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Teacher
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Stefani Alessandro
(syllabus)
• Approach to the patient with neurological diseases
• Language abnormalities
• Neurobiological mechanisms of spasticity and rigidity and treatment approach
• Imaging (MRI, CT scan) and electrophysiologic techniques (evoked potentials, electromyo-grography, electroneurography, electroencephalography) for neurologic diagnosis
• Synaptic plasticity and neurobiology of rehabilitation
• Cerebrovascular diseases
• Multiple sclerosis and other inflammatory demyelinating diseases
• Motorneurons disease
• Parkinson’s disease and other movement disorders
• Alzheimer’s disease and other neurodegenerative disorders
• Genetic and acquired diseases of the peripheral nerves
• Myasthenia gravis and other diseases of the neuromuscular junction
• Infections of the nervous system (viral including SARS, bacterial, prionic
(reference books)
• Adams and Victor's Principles of Neurology 11th ed. McGraw-Hill Medical
• Fuller G. Neurological Examination Made Easy Ed. Churchill Livingstone
• www.pubmed.com
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Dates of beginning and end of teaching activities
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From to |
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Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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| Module: Neurosurgery
(objectives)
Pharmacology
After completing the course, students should be able to:
- understand and describe the basic principles of pharmacology, in particular notions of pharmacokinetics and pharmacodynamics, and the experimental phases for the development of new drugs. Students will also know the main pharmacological strategies used for anticancer and antibacterial therapies, for the treatment of inflammation, pain, cardiovascular, respiratory and neurological diseases.
- describe the mechanisms of damage subtending the most common diseases affecting the central and the peripheral nervous system and their clinical and instrumental diagnostic process. Particular attention must be paid to the description of the neurobiological mechanisms favoring the recovery from acute and chronic neuronal damage as well as the mechanisms that support plasticity, including functional properties of circuitries.
- acquire scientific and medico-clinical knowledge necessary to identify, define, frame and possibly classify the neurosurgical pathologies most commonly encountered in daily clinical practice
- understand the pathophysiological mechanisms that led to the "neurological deficit", knowing how to trace its origin and how to define its anatomical-clinical features.
- know the the fundamentals of psychopathology and the history of psychiatry.
- know the basic mechanisms of of pathophysiology, the clinic and the treatment of the main psychiatric disorders.
|
|
Language
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ENG |
|
Type of certificate
|
Profit certificate
|
|
Credits
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2
|
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Scientific Disciplinary Sector Code
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MED/27
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Contact Hours
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20
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Type of Activity
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Core compulsory activities
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Teacher
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Tomasi Santino Ottavio
(syllabus)
Principles of Neuro-anatomy and Physiology: the Cranio-Cerebral System.
• Topographic Anatomy of the skull and skullbase; functional Anatomy of the brain and brainstem; functional networks of the central nervous system. Anatomy and physiology of the cranial nerves. Anatomy and physiology of the cerebral blood vessels. Anatomy and physiology of the ventriculo-cisternal system.
Pathophysiology of Intracranial Pressure (ICP).
• Homeostasis of intracranial volumes. Definition of ICP. The Pressure-volume relationship. Cerebral Perfusion Pressure. Cerebral Blood Flow. Cerebral Edema. Syndrome of elevated ICP.
Cerebro-spinal fluid (CSF) related pathologies.
• CSF: Intrinsic proprieties, production and reabsorption. CSF dynamics. Hydrocephalus: classification and pathophysiology. Normal Pressure Hydrocephalus. Syringomyelia. Pseudotumor Cerebri.
Brain Tumors.
• Principles of Neuro-oncology. W.H.O. Classification. Gliomas. Meningiomas. Tumor of the sellar region. Other primitive cerebral tumors. Secondary tumors (metastasis0.
Traumatic Brain Injury (TBI).
• Biomechanical aspects. State of consciousness alteration. Post-traumatic intracranial bleedings. Traumatic fracture of the skull and skullbase fractures. Diffuse axonal injury. Brain Concussion. Outcomes following TBI.
Spontaneous Intracranial Hemorrhages.
• Hemorrhagic Strokes. Subarachnoid hemorrhage. Intracranial aneurysms. Artero-venous malformations. Intracerebral hematomas (epidural, subdural, intraparenchymal). Related Outcomes.
Principles of Neuro-anatomy and Physiology: the vertebro-medullary system.
• General anatomy of the spine. The cranio-vertebral junction. Anatomy and functional organization of the spinal cord. Spinal nerves and spinal roots. Topographic anatomy of the cervical, dorsal and lumbo-sacral spine and the related spinal cord segments.
Traumatic Spinal Injury (TSI).
• Biomechanical aspects. Principles of vertebral fractures classification. Post-traumatic spinal cord syndromes. The A.S.I.A. system. Outcome following TSI.
Spinal Tumors.
• Classification and general aspects. Primary and secondary tumors. Spinal cord compression syndromes. Prognosis of spinal tumors.
Spinal degenerative disease.
• Low back pain. Radiculopathy. Myelopathy. Disks degeneration and related pathology. Spinal stenosis. The concept of spinal instability. Spondylosis and spondylolisthesis.
(reference books)
During each lesson the teacher will support the student with an abundant source of references, indicating the most important and recent literature to read. Fundamental Book Chapters will be also provided, directly by the teacher. All teaching materials will be provided to students and will be accessible on the university portal.
Recommended texts:
Greenberg’s Handbook of Neurosurgery, by Mark Greenberg - Thieme
Diagnostic and Surgical Imaging Anatomy: Brain, Head & Neck, Spine, by Harnsberger, Osborn, MacDonald, Ross – Amirsys
Diagnostic Neuroradiology, by Anne G. Osborn - Mosby
Diagnostic Cerebral Angiography, by Anne G. Osborn – Lippincott Williams & Wilkins
Neurosurgery Knowledge Update, by Harbaugh, Shaffrey, Couldwell, Berger -Thieme
Neurosurgery fundamentals. Ed. Nitin Agarwal - New York: Thieme
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Dates of beginning and end of teaching activities
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From to |
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Delivery mode
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Traditional
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Attendance
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Mandatory
|
|
Evaluation methods
|
Written test
Oral exam
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| Module: Pharmacology
(objectives)
Pharmacology
After completing the course, students should be able to:
- understand and describe the basic principles of pharmacology, in particular notions of pharmacokinetics and pharmacodynamics, and the experimental phases for the development of new drugs. Students will also know the main pharmacological strategies used for anticancer and antibacterial therapies, for the treatment of inflammation, pain, cardiovascular, respiratory and neurological diseases.
- describe the mechanisms of damage subtending the most common diseases affecting the central and the peripheral nervous system and their clinical and instrumental diagnostic process. Particular attention must be paid to the description of the neurobiological mechanisms favoring the recovery from acute and chronic neuronal damage as well as the mechanisms that support plasticity, including functional properties of circuitries.
- acquire scientific and medico-clinical knowledge necessary to identify, define, frame and possibly classify the neurosurgical pathologies most commonly encountered in daily clinical practice
- understand the pathophysiological mechanisms that led to the "neurological deficit", knowing how to trace its origin and how to define its anatomical-clinical features.
- know the the fundamentals of psychopathology and the history of psychiatry.
- know the basic mechanisms of of pathophysiology, the clinic and the treatment of the main psychiatric disorders.
|
|
Language
|
ENG |
|
Type of certificate
|
Profit certificate
|
|
Credits
|
2
|
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Scientific Disciplinary Sector Code
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BIO/14
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Contact Hours
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20
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Type of Activity
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Basic compulsory activities
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Teacher
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Consalvi Silvia
(syllabus)
• General principles of pharmacology.
• Development of new drugs and study phases. Clinical trial of drugs.
• Pharmacodynamics: mechanism of action of agonist and antagonist drugs, receptors and signaling pathways
• Pharmacokinetics: factors influencing it, drug elimination and biotransformation.
• Gene therapy and Epigenetic therapy.
• Treatment of pain and inflammation: glucocorticoids, NSAIDs, opioid analgesics.
• Cardiovascular therapy.
• Drugs for the treatment of asthma and anaphylactic shock.
• Sedative-hypnotic drugs for the treatment of insomnia and anxiety.
• Pharmacology of neurodegenerative diseases: drugs for the treatment of Parkinson's disease.
• Antibacterial chemotherapy.
• Antineoplastic chemotherapy, general principles of Target Therapy.
(reference books)
Bertram G. Katzung. Basic and Clinical Pharmacology. 15th edition, 2021.
- Slides fornite dal docente.
- Bertram G. Katzung. Basic and Clinical Pharmacology. 15th edition, 2021.
- Slide sets provided by the teacher.
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Dates of beginning and end of teaching activities
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From to |
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Delivery mode
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Traditional
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Attendance
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Mandatory
|
|
Evaluation methods
|
Written test
Oral exam
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|
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| Module: Psychiatry
(objectives)
Pharmacology
After completing the course, students should be able to:
- understand and describe the basic principles of pharmacology, in particular notions of pharmacokinetics and pharmacodynamics, and the experimental phases for the development of new drugs. Students will also know the main pharmacological strategies used for anticancer and antibacterial therapies, for the treatment of inflammation, pain, cardiovascular, respiratory and neurological diseases.
- describe the mechanisms of damage subtending the most common diseases affecting the central and the peripheral nervous system and their clinical and instrumental diagnostic process. Particular attention must be paid to the description of the neurobiological mechanisms favoring the recovery from acute and chronic neuronal damage as well as the mechanisms that support plasticity, including functional properties of circuitries.
- acquire scientific and medico-clinical knowledge necessary to identify, define, frame and possibly classify the neurosurgical pathologies most commonly encountered in daily clinical practice
- understand the pathophysiological mechanisms that led to the "neurological deficit", knowing how to trace its origin and how to define its anatomical-clinical features.
- know the the fundamentals of psychopathology and the history of psychiatry.
- know the basic mechanisms of of pathophysiology, the clinic and the treatment of the main psychiatric disorders.
|
|
Language
|
ENG |
|
Type of certificate
|
Profit certificate
|
|
Credits
|
1
|
|
Scientific Disciplinary Sector Code
|
MED/25
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Contact Hours
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10
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Type of Activity
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Core compulsory activities
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Teacher
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Chiappini Stefania
(syllabus)
Introduction to psychiatry
• Notes on history of psychiatry
• Elements of psychopathology
The main psychiatric disorders and their treatment:
• Schizophrenia
• Mood disorders
• Anxiety disorders
• Obsessive Compulsive Disorder
• Disorders associated with traumatic or stressful events
• Personality disorders
• Hysteria and disorders with somatic symptoms
• Eating disorders
• Substance Use Disorder and Behavioral Addictions
Legislation and organization of territorial psychiatric assistance.
(reference books)
• A Short Textbook of Psychiatry: 20th Year Edition by Niraj Ahuja, Jaypee Brothers Medical Pub
• Handbook of psychopathology
Giovanni Martinotti
Fila 37 Editore
EAN: 9788899235222
ISBN: 8899235228
• Martinotti G. Handbook of Psychopathology. Ed. Fila 37, 2023
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Dates of beginning and end of teaching activities
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From to |
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Delivery mode
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Traditional
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Attendance
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Mandatory
|
|
Evaluation methods
|
Written test
Oral exam
|
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