(objectives)
The pathophysiology course aims to provide students with the basics of cellular pathology, general pathology, immunology, and pathophysiology related to human nutrition. The student should learn the pathogenesis of diseases at the cellular and tissue level, the mechanisms of the cell and organism response to injury, and the mechanisms of the innate and acquired immune response that underlie the pathogenesis of adverse reactions to food. Acquire a knowledge of the principles of pharmacology, pharmacodynamics and pharmacokinetics. Acquire a knowledge on the role of pharmacotherapy and diet in the prevention and treatment of chronic non-communicable degenerative diseases and COVID-19. Acquire a knowledge on the interactions between drugs, supplements and foods, in particular on the role of drugs and supplements on the intestinal microbiota.
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Code
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90680 |
Language
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ITA |
Type of certificate
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Profit certificate
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Module:
(objectives)
Acquire a knowledge of the principles of pharmacology, pharmacodynamics and pharmacokinetics. Acquire a knowledge on the role of pharmacotherapy and diet in the prevention and treatment of chronic non-communicable degenerative diseases and COVID-19. Acquire a knowledge on the interactions between drugs, supplements and foods, in particular on the role of drugs and supplements on the intestinal microbiota.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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7
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Scientific Disciplinary Sector Code
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BIO/14
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Contact Hours
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-
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Type of Activity
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Core compulsory activities
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Teacher
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Sorrentino Maria
(syllabus)
Pharmacology, general principles - Pharmacodynamics, mechanisms of action of drugs and concentration-effect relationship. Drug-receptor interaction response. - Pharmacokinetics principles applied to therapy: dynamics of drug absorption, distribution and elimination. Routes of drug administration, absorption and distribution. • Drug metabolism, enzymatic drug induction and inhibition, drug elimination. - Pharmacological interactions: pharmaceutical, pharmacodynamic, pharmacokinetic. - Drug-drug interaction. - Nutrients pharmacology: pharmacology principle of food supplements; botanical and nutritional supplements; Fat-soluble and water-soluble vitamins: trace elements and polyphenols. - Drug-food interactions - Effect of drugs on nutritional status: influence of drugs on nutrient absorption; drugs modulation of hunger and satiety; Drugs that interfere with the perception of taste; malabsorption-inducing drugs - Drugs active on the gastrointestinal system: classification and mechanism of action of drugs. Drug therapy of acid-peptic-gastrointestinal disorders; laxatives. - Pharmacology of the metabolic endocrine system. - Drugs for the control of glucose metabolism. - Gut microbiota: interactions between drugs, prebiotics, probiotics, postbiotics and polyphenols on the microbiota - Anticancer drugs: classification and mechanism of action; interaction of oncological drugs and nutrients; immunonutrition and cancer. - Antiviral drugs - COVID19: pharmacological therapy and immunonutrition.
(reference books)
Galli C., Gatti E., Tomassi G., Visioli F. Farmacologia e nutrizione. UTET F Clementi, G Fumagalli. Farmacologia Generale e Molecolare. UTET Goodman & Gilman. Le Basi Farmacologiche della Terapia. Zanichelli 2019 Richard D. Howland, Mary J. Mycek. Le Basi della Farmacologia, nuova edizione. Zanichelli 2007 I docenti forniranno eventuale materiale didattico suppletivo.
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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At a distance
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Attendance
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not mandatory
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Evaluation methods
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Written test
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Teacher
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Bigioni Mario
(syllabus)
Pharmacology, general principles - Pharmacodynamics, mechanisms of action of drugs and concentration-effect relationship. Drug-receptor interaction response. - Pharmacokinetics principles applied to therapy: dynamics of drug absorption, distribution and elimination. Routes of drug administration, absorption and distribution. • Drug metabolism, enzymatic drug induction and inhibition, drug elimination. - Pharmacological interactions: pharmaceutical, pharmacodynamic, pharmacokinetic. - Drug-drug interaction. - Nutrients pharmacology: pharmacology principle of food supplements; botanical and nutritional supplements; Fat-soluble and water-soluble vitamins: trace elements and polyphenols. - Drug-food interactions - Effect of drugs on nutritional status: influence of drugs on nutrient absorption; drugs modulation of hunger and satiety; Drugs that interfere with the perception of taste; malabsorption-inducing drugs - Drugs active on the gastrointestinal system: classification and mechanism of action of drugs. Drug therapy of acid-peptic-gastrointestinal disorders; laxatives. - Pharmacology of the metabolic endocrine system. - Drugs for the control of glucose metabolism. - Gut microbiota: interactions between drugs, prebiotics, probiotics, postbiotics and polyphenols on the microbiota - Anticancer drugs: classification and mechanism of action; interaction of oncological drugs and nutrients; immunonutrition and cancer. - Antiviral drugs - COVID19: pharmacological therapy and immunonutrition.
(reference books)
Galli C., Gatti E., Tomassi G., Visioli F. Farmacologia e nutrizione. UTET F Clementi, G Fumagalli. Farmacologia Generale e Molecolare. UTET Farmacologia generale e speciale per le lauree sanitarie. A cura di Anna Maria Di Giulio et al. Seconda edizione luglio 2018, Piccin. Richard D. Howland, Mary J. Mycek. Le Basi della Farmacologia, nuova edizione. Zanichelli 2007 I docenti forniranno eventuale materiale didattico suppletivo.
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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At a distance
|
Attendance
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not mandatory
|
Evaluation methods
|
Written test
|
|
|
Module:
(objectives)
The pathophysiology course aims to provide students with the basics of cellular pathology, general pathology, immunology, and pathophysiology related to human nutrition. The student should learn the pathogenesis of diseases at the cellular and tissue level, the mechanisms of the cell and organism response to injury, and the mechanisms of the innate and acquired immune response that underlie the pathogenesis of adverse reactions to food.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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4
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Scientific Disciplinary Sector Code
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MED/04
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Contact Hours
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-
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Type of Activity
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Related or supplementary learning activities
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Teacher
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Benvenuto Monica
(syllabus)
• Cellular pathology: Cellular stress, Necrosis, Apoptosis. Cellular adaptations • Innate immunity. Acute inflammation. Cells and chemical mediators of inflammation. Exudation: different types of exudate. Chemotaxis and phagocytosis. Chronic inflammation • Adaptive immunity: immune tolerance. Oral tolerance. Antigens and antibodies. Antigen recognition and lymphocyte activation. Major histocompatibility system. Antigen processing and presentation to T lymphocytes. Regulation of the immune response. Effector mechanisms of the immune response. Hypersensitivity reactions. Gut barrier • Adverse food reactions: pathogenetic aspects • Food allergies: pathogenesis, classification of food allergens • Pathogenesis of anaphylactic shock. Celiac disease • Food intolerances: pathogenesis. Pseudoallergic food reactions. Enzyme deficiency reactions.
(reference books)
-Slides and didactic materials provided by the teacher. -Textbooks: Pontieri GM; Elementi di Patologia Generale e Fisiopatologia Generale; 4 edizione; Piccin Ed; ISBN: 9788829929122; 2018 Abbas AK, Lichtman AH, Pillai S; Le basi dell’immunologia; 5 edizione; Edra.; ISBN: 9788821442551; 2017 Kumar V, Abbass AK, Aster JC; Robbins, Fondamenti di Patologia e di Fisiopatologia; 9 edizione; Edra; ISBN: 9788821440458; 2013
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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At a distance
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Attendance
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not mandatory
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Evaluation methods
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Written test
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