| Laboratory medicine
(objectives)
The integrated teaching of Laboratory Medicine is aimed at introducing the student to the logic and tools underlying the execution of the diagnostic tests of the Clinical Biochemistry, Clinical Pathology, Clinical Microbiology, Clinical Parasitology and Rheumatology. At the end of the integrated teaching, the student will be able to apply diagnostic tests in the clinical practice, and to interpret and evaluate their results.
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Code
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90291 |
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Language
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ENG |
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Type of certificate
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Profit certificate
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| Module: Clinical biochemistry and clinical molecular biochemistry
(objectives)
AA 2022/2023
The teaching of Clinical Biochemistry and Clinical Molecular Biology aims to provide the student with the theoretical-practical knowledge of the basic principles of Biochemistry and Molecular Biology underlying the execution and evaluation of laboratory diagnostic tests. The student will have to know and be able to understand the problems related to the organization of the laboratory, the management and operation of diagnostic devices, the methodological rigor, the rationale for carrying out the analyzes, the quality control of biochemical-molecular tests applied to clinical-diagnostic areas of survey and adequately understand the applicative implications of Biochemistry and Molecular Biology both in the clinical field and in the field of modern technologies.
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Language
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ENG |
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Type of certificate
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Profit certificate
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Credits
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2
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Scientific Disciplinary Sector Code
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BIO/12
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Contact Hours
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20
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Type of Activity
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Core compulsory activities
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Group: CANALE A
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Teacher
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Pieroni Luisa
(syllabus)
AA2022/2023
• Definition, limits and aims of Laboratory Medicine
• Classification of disciplines falling within the scope of Laboratory Medicine.
• General organization of the Laboratory: from the request for analysis to the report.
• Reference ranges, critical values
• Sources of variability in the preanalytical and analytical phase, intra and interindividual biological variability, concepts of diagnostic sensitivity and specificity and their applications. Internal and external quality control
• Balance of body fluids and electrolytes. Acid-base balance. Conditions associated with abnormal electrolyte composition or acid-base balance
• Plasma proteins and enzymes as biomarkers of tissue and organ damage. Evaluation of plasma / serum enzymes and metabolites for diagnostic purposes. General characteristics, biochemical role and methods of dosage of the main enzymes of clinical interest: LDH, CPK, AST and ALT, alkaline phosphatase, cholinesterase.
• Introduction to Clinical Molecular Biology and Molecular Biomarkers
• Methods of preparation and analysis of proteins and nucleic acids used in clinical diagnostic (e.g. immuno-detections and immunoassays of proteins, protein and nucleic acid electrophoresis, PCR, gene sequencing, arrays, LC-MS, etc)
• Molecular diagnostic tests (genetic and oncological diseases)
• Introduction to omics sciences and their application in diagnostics
(reference books)
• Nader Rifai, Rossa W.K. Chiu. Ian Young, Carey-Ann D.Burnham, Carl T. Wittwer “Tietz Textbook of Laboratory Medicine.” (7th Edition). Elsevier Health Sciences (US), Available from: VitalSource Bookshelf
• Michael J. Murphy & Rajeev Srivastava & Kevin Deans “Clinical Biochemistry”, Sixth Edition , Elsevier
• Michael M. Cox, Jennifer Doudna, Michael O'Donnell. “Molecular Biology: Principles and Practice”; W H Freeman & Co; 2 edition
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Dates of beginning and end of teaching activities
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From to |
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Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Group: CANALE B
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Teacher
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Pieroni Luisa
(syllabus)
AA2022/2023
Definition, limits and aims of Laboratory Medicine
• Classification of disciplines falling within the scope of Laboratory Medicine.
• General organization of the Laboratory: from the request for analysis to the report.
• Reference ranges, critical values
• Sources of variability in the preanalytical and analytical phase, intra and interindividual biological variability, concepts of diagnostic sensitivity and specificity and their applications. Internal and external quality control
• Balance of body fluids and electrolytes. Acid-base balance. Conditions associated with abnormal electrolyte composition or acid-base balance
• Plasma proteins and enzymes as biomarkers of tissue and organ damage. Evaluation of plasma / serum enzymes and metabolites for diagnostic purposes. General characteristics, biochemical role and methods of dosage of the main enzymes of clinical interest: LDH, CPK, AST and ALT, alkaline phosphatase, cholinesterase.
• Introduction to Clinical Molecular Biology and Molecular Biomarkers
• Methods of preparation and analysis of proteins and nucleic acids used in clinical diagnostic (e.g. immuno-detections and immunoassays of proteins, protein and nucleic acid electrophoresis, PCR, gene sequencing, arrays, LC-MS, etc)
• Molecular diagnostic tests (genetic and oncological diseases)
• Introduction to omics sciences and their application in diagnostics
(reference books)
AA2022/2023
• Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor
• Michael J. Murphy & Rajeev Srivastava & Kevin Deans “Clinical Biochemistry”, Sixth Edition , Elsevier
• Michael M. Cox, Jennifer Doudna, Michael O'Donnell. “Molecular Biology: Principles and Practice”; W H Freeman & Co; 2 edition
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Dates of beginning and end of teaching activities
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From to |
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Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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| Module: Clinical pathology
(objectives)
The integrated teaching of Laboratory Medicine is aimed at introducing the student to the logic and tools underlying the execution of the diagnostic tests of the Clinical Biochemistry, Clinical Pathology, Clinical Microbiology, Clinical Parasitology and Rheumatology. At the end of the integrated teaching, the student will be able to apply diagnostic tests in the clinical practice, and to interpret and evaluate their results.
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Language
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ENG |
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Type of certificate
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Profit certificate
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Credits
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2
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Scientific Disciplinary Sector Code
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MED/05
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Contact Hours
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20
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Type of Activity
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Core compulsory activities
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Group: CANALE A
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Teacher
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Barillari Giovanni
(syllabus)
- The clinical value of the laboratory
- Injury and function markers
- The blood count
- Coagulation and pathologies of the coagulation system
- Markers of inflammation and immune reactions
- Diagnosis of leukocyte pathologies
- Diagnosis of anemias
- Liver, hepatitis and cirrhosis
- Blood sugar
- Lipemia
- Functional evaluation of the kidney, urinalysis
- Tumor markers
- Immunohematology and transfusion medicine
- Laboratory evaluation of drug blood concentrations, drug abuse and doping
- The laboratory in sport activities
(reference books)
- “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446
- Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor
- Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke - Second edition
- Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition
- Harrison’s Rheumatology, latest edition
- Harrison’s Principle of Internal Medicine, latest edition
- Oxford Handbook of Rheumatology, latest edition
- Clinical Microbiology, Murray, Rosenthal, Pfaller, 8 Edition
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Dates of beginning and end of teaching activities
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From to |
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Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Group: CANALE B
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Teacher
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Barillari Giovanni
(syllabus)
Clinical Pathology
• The clinical value of the laboratory.
• Injury and function markers.
• The blood count.
• Coagulation and pathologies of the coagulation system.
• Markers of inflammation and immune reactions.
• Diagnosis of leukocyte pathologies.
• Diagnosis of anemias.
• Liver, hepatitis and cirrhosis.
• Blood sugar.
• Lipemia
• Functional evaluation of the kidney, urinalysis.
• Tumor markers.
• Immunohematology and transfusion medicine.
• Laboratory evaluation of drug blood concentrations, drug abuse and doping.
• The laboratory in sport activities.
(reference books)
RECOMMENDED TEXTBOOKS
• “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446
• Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor
• Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke
Second edition
• Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition
• Harrison’s Rheumatology, latest edition
• Harrison’s Principle of Internal Medicine, latest edition
• Oxford Handbook of Rheumatology, latest edition
• Clinical Microbiology, Murray, Rosenthal, Pfaller, 8 Edition
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Dates of beginning and end of teaching activities
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From to |
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Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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| Module: Microbiology and clinical microbiology
(objectives)
The integrated teaching of Laboratory Medicine is aimed at introducing the student to the logic and tools underlying the execution of the diagnostic tests of the Clinical Biochemistry, Clinical Pathology, Clinical Microbiology, Clinical Parasitology and Rheumatology. At the end of the integrated teaching, the student will be able to apply diagnostic tests in the clinical practice, and to interpret and evaluate their results.
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Language
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ENG |
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Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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MED/07
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Contact Hours
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10
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Personal Study Hours
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-
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Type of Activity
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Core compulsory activities
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Credits
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1
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Scientific Disciplinary Sector Code
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MED/07
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Contact Hours
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10
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Personal Study Hours
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-
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Type of Activity
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Core compulsory activities
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Group: CANALE A
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Teacher
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Perno Carlo Federico
(syllabus)
- Principles of medical microbiology and immunology
- Principles of diagnostic microbiology
◦ Tests used
◦ Appropriate biological samples
◦ How to get and store biological samples
◦ Interpretation of microbiological results
- Elements of Diagnostic Microbiology: Direct and indirect tests, Microbial isolation, selection of the appropriate biological samples, antibiogram (Principles, purposes and interpretation)
- Elements of Diagnostic Virology: Direct and indirect tests, Viral isolation, Selection of the biological samples and their preservation and storage
- Elements of the diagnostic Mycology, biological isolation, selection of the biological samples; modern molecular and antigenic tests
- Main etiological agents of the infections of the Nervous System; Characteristics of the cerebrospinal fluid. Samples to be used, how to get them, storage, interpretation of the results
- Main etiological agents of the infections of the Upper and Lower Respiratory Tracts. Samples to be used, how to get them, storage, interpretation of the results
- Main etiological agents of the infections of the Gastrointestinal System. Food-related infections. Samples to be used, how to get them, storage, interpretation of the results
- Main etiological agents of the infections of the Urinary Tract. Samples to be used, how to get them, storage, interpretation of the results
- Systemic infections: How to use and interpret the Haemoculture. Infections of the cardio-vascular apparatus
- Main etiological agents of the infections of the Genital Tract. Infections during pregnancy. Samples to be used, how to get them, storage, interpretation of the results
- Sexually transmitted diseases. Main etiological agents, samples to be used, how to get them, storage, interpretation of the results
- Diagnosis of HIV and viral hepatitis
- Hospital infections: Main etiological agents and their modern diagnosis. Microbiological control of the hospital infections
- Infections in the immunocompromised host; Etiological agents, Modern diagnosis, Samples used, how to get them, storage, interpretation of the results
- Microbiota: Structure, clinical relevance, diagnostic methodologies
- General information about the rapid diagnosis of malaria
(reference books)
- “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446
- Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor
- Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke - Second edition
- Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition
- Harrison’s Rheumatology, latest edition
- Harrison’s Principle of Internal Medicine, latest edition
- Oxford Handbook of Rheumatology, latest edition
- Clinical Microbiology, Murray, Rosenthal, Pfaller, 8 Edition
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Dates of beginning and end of teaching activities
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From to |
|
Delivery mode
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Traditional
|
|
Attendance
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Mandatory
|
|
Evaluation methods
|
Written test
Oral exam
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Group: CANALE B
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Teacher
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Perno Carlo Federico
(syllabus)
Microbiology and Clinical Microbiology
• Principles of medical microbiology and immunology
• Principles of diagnostic microbiology
◦ Tests used
◦ Appropriate biological samples
◦ How to get and store biological samples
◦ Interpretation of microbiological results
• Elements of Diagnostic Microbiology: Direct and indirect tests, Microbial isolation, selection of the appropriate biological samples, antibiogram (Principles, purposes and interpretation)
• Elements of Diagnostic Virology: Direct and indirect tests, Viral isolation, Selection of the biological samples and their preservation and storage
• Elements of the diagnostic Mycology, biological isolation, selection of the biological samples; modern molecular and antigenic tests
• Main etiological agents of the infections of the Nervous System; Characteristics of the cerebrospinal fluid. Samples to be used, how to get them, storage, interpretation of the results
• Main etiological agents of the infections of the Upper and Lower Respiratory Tracts. Samples to be used, how to get them, storage, interpretation of the results
• Main etiological agents of the infections of the Gastrointestinal System. Food-related infections. Samples to be used, how to get them, storage, interpretation of the results
• Main etiological agents of the infections of the Urinary Tract. Samples to be used, how to get them, storage, interpretation of the results
• Systemic infections: How to use and interpret the Haemoculture. Infections of the cardio-vascular apparatus
• Main etiological agents of the infections of the Genital Tract. Infections during pregnancy. Samples to be used, how to get them, storage, interpretation of the results
• Sexually transmitted diseases. Main etiological agents, samples to be used, how to get them, storage, interpretation of the results
• Diagnosis of HIV and viral hepatitis
• Hospital infections: Main etiological agents and their modern diagnosis. Microbiological control of the hospital infections.
• Infections in the immunocompromised host; Etiological agents, Modern diagnosis, Samples used, how to get them, storage, interpretation of the results
• Microbiota: Structure, clinical relevance, diagnostic methodologies
• General information about the rapid diagnosis of malaria
(reference books)
RECOMMENDED TEXTBOOKS
• “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446
• Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor
• Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke
Second edition
• Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition
• Harrison’s Rheumatology, latest edition
• Harrison’s Principle of Internal Medicine, latest edition
• Oxford Handbook of Rheumatology, latest edition
• Clinical Microbiology, Murray, Rosenthal, Pfaller, 8 Edition
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Dates of beginning and end of teaching activities
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From to |
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Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
|
Written test
Oral exam
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| Module: Clinical parasitology
(objectives)
The integrated teaching of Laboratory Medicine is aimed at introducing the student to the logic and tools underlying the execution of the diagnostic tests of the Clinical Biochemistry, Clinical Pathology, Clinical Microbiology, Clinical Parasitology and Rheumatology. At the end of the integrated teaching, the student will be able to apply diagnostic tests in the clinical practice, and to interpret and evaluate their results.
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Language
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ENG |
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Type of certificate
|
Profit certificate
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|
Credits
|
1
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Scientific Disciplinary Sector Code
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VET/06
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Contact Hours
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10
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Type of Activity
|
Core compulsory activities
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Group: CANALE A
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Teacher
|
Putignani Lorenza
(syllabus)
- Concepts of ecology applied to parasitism
- General clinical parasitology principles regarding transmission routes, zoonosis, anthropozoonosis
- Medically important Parasites belonging to Nematodes and Cestodes. Laboratory diagnosis of parasitic diseases, clinical symptoms and treatment
(reference books)
- “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446
- Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor
- Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke - Second edition
- Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition
- Harrison’s Rheumatology, latest edition
- Harrison’s Principle of Internal Medicine, latest edition
- Oxford Handbook of Rheumatology, latest edition
- Clinical Microbiology, Murray, Rosenthal, Pfaller, 8 Edition,
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Dates of beginning and end of teaching activities
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From to |
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Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
|
Written test
Oral exam
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Group: CANALE B
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Teacher
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Putignani Lorenza
(syllabus)
Clinical Parasitology
• Concepts of ecology applied to parasitism;
• General clinical parasitology principles regarding transmission routes, zoonosis, anthropozoonosis;
• Medically important Parasites belonging to Nematodes and Cestodes. Laboratory diagnosis of parasitic diseases, clinical symptoms and treatment
(reference books)
RECOMMENDED TEXTBOOKS
• “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446
• Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor
• Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke
Second edition
• Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition
• Harrison’s Rheumatology, latest edition
• Harrison’s Principle of Internal Medicine, latest edition
• Oxford Handbook of Rheumatology, latest edition
• Clinical Microbiology, Murray, Rosenthal, Pfaller, 8 Edition
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Dates of beginning and end of teaching activities
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From to |
|
Delivery mode
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Traditional
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|
Attendance
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Mandatory
|
|
Evaluation methods
|
Written test
Oral exam
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|
|
| Module: Rheumatology
(objectives)
The integrated teaching of Laboratory Medicine is aimed at introducing the student to the logic and tools underlying the execution of the diagnostic tests of the Clinical Biochemistry, Clinical Pathology, Clinical Microbiology, Clinical Parasitology and Rheumatology. At the end of the integrated teaching, the student will be able to apply diagnostic tests in the clinical practice, and to interpret and evaluate their results.
|
|
Language
|
ENG |
|
Type of certificate
|
Profit certificate
|
|
Credits
|
1
|
|
Scientific Disciplinary Sector Code
|
MED/16
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Contact Hours
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10
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Type of Activity
|
Core compulsory activities
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Group: CANALE A
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Teacher
|
Priori Roberta
(syllabus)
- Classification of rheumatic diseases
- Autoimmune and inflammatory disorders of rheuatologic interest: pathogenesis, clinical presentation, epidemiology, course, basic management and prognosis
- The role of laboratory investigations for the diagnosis of rheumatic diseases
- Sjogren’s syndrome
- Systemic Lupus Erythematosus
- Systemic sclerosis
- Mixed connective tissue disease
- Undifferentiated connective tissue disease
- Antiphospholipid antibodies syndrome
- Idiopatic Inflammatory myopathies
- Systemic Vasculitis
- Autoinflammatory diseases
- Introduction to rheumatoid arthritis
(reference books)
- “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446
- Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor
- Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke - Second edition
- Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition
- Harrison’s Rheumatology, latest edition
- Harrison’s Principle of Internal Medicine, latest edition
- Oxford Handbook of Rheumatology, latest edition
- Clinical Microbiology, Murray, Rosenthal, Pfaller, 8 Edition
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Dates of beginning and end of teaching activities
|
From to |
|
Delivery mode
|
Traditional
|
|
Attendance
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Mandatory
|
|
Evaluation methods
|
Written test
Oral exam
|
Group: CANALE B
|
Teacher
|
Priori Roberta
(syllabus)
Rheumatology
• Classification of rheumatic diseases.
• Autoimmune and inflammatory disorders of rheuatologic interest: pathogenesis, clinical presentation, epidemiology, course, basic management and prognosis.
• The role of laboratory investigations for the diagnosis of rheumatic diseases.
• Sjogren’s syndrome.
• Systemic Lupus Erythematosus.
• Systemic sclerosis.
• Mixed connective tissue disease.
• Undifferentiated connective tissue disease.
• Antiphospholipid antibodies syndrome.
• Idiopatic Inflammatory myopathies.
• Systemic Vasculitis.
• Autoinflammatory diseases.
• Introduction to rheumatoid arthritis.
(reference books)
RECOMMENDED TEXTBOOKS
• “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446
• Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor
• Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke
Second edition
• Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition
• Harrison’s Rheumatology, latest edition
• Harrison’s Principle of Internal Medicine, latest edition
• Oxford Handbook of Rheumatology, latest edition
• Clinical Microbiology, Murray, Rosenthal, Pfaller, 8 Edition
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|
Dates of beginning and end of teaching activities
|
From to |
|
Delivery mode
|
Traditional
|
|
Attendance
|
Mandatory
|
|
Evaluation methods
|
Written test
Oral exam
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|
