Biology, Applied Physics, Biochemistry
(objectives)
Aim of the teaching is to provide students with knowledge on the fundamentals of applied physics necessary to the performance of their future activity. In particular, the comprehension of physical principles at the base of medical physics and of functioning of medical instrumentation will be addressed. At the end of the course, the students will know the fundamental concepts of application of the Scientific Method to the study of biomedical phenomena (choice and measure of parameters, evaluation of errors), they will be able to describe physical phenomena of complex systems using suitable mathematical tools, they will know the scientific basis of medical procedures and principles of functioning of the equipment commonly used for diagnostics and therapeutics. Students will learn knowledge on the structure, function and regulation of biological macromolecules (carbohydrates, lipids, amino acids and proteins). To acquire basic knowledge on the main metabolic pathways and cycles with particular regard to carbohydrate, lipid and amino acid metabolism. Students will learn with knowledge based on inheritance of monogenic, chromosomal and multifactorial diseases. At the end of the course the student will be able to distinguish the main classes of genetic diseases and to recognize the modes of transmission of hereditary diseases. Students will learn knowledge related to the physiological and morphological characteristics of cells, as functional units of living organisms. Another important goal is to use the scientific method to understand the biological mechanisms that regulate life and as a tool for the study of pathological processes.
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Code
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90193 |
Language
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ENG |
Type of certificate
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Profit certificate
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Module: Biophysics
(objectives)
The purpose of teaching is to provide students with the knowledge necessary for the performance of their future work. In particular, the comprehension of the physical principles underlying medical physics and the operation of medical instrumentation will be addressed. By the end of the course, students will know the basic concepts of applying the Scientific Method to the study of biomedical phenomena (choice and measurement of parameters, evaluation of errors). They will be able to describe physical phenomena of complex systems using appropriate mathematical tools, they will know the scientific basis of medical procedures and the principles of operation of equipment commonly used for diagnostics and therapy. They will acquire basic knowledge about the structure and function of biological macromolecules (carbohydrates, lipids, amino acids and proteins); basic knowledge about the main metabolic pathways and cycles with special emphasis on glucose, lipid and amino acid metabolism; knowledge about the morphological and physiological characteristics of the cell as a functional unit of living organisms. Another important objective will be the application of the experimental method as a means of understanding the biological mechanisms that regulate life and a tool for the study of pathological processes. At the end of the course the student will also be able to distinguish the main classes of genetic, monogenic, chromosomal and multifactorial diseases and recognize their modes of transmission.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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BIO/09
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Contact Hours
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14
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Type of Activity
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Basic compulsory activities
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Teacher
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Nicolai Eleonora
(syllabus)
• Fundamental and derived physical quantities • Dimensional equations • Scientific Notation • Orders of Greatness • Scalar and vector quantities • Vectors Mechanics • Kinematics • Uniform rectilinear motion • Rectilinear motion uniformly accelerated • Graphic representation of the motions • Uniform circular motion Dynamics • Fundamental forces • Principles of dynamics: Newton's I, II, III law • Translational equilibrium • Inertial and non-inertial reference systems • Inertial mass concept • Gravitational force • Strength weight • Normal force to the supporting surface • Tension of a rope • Frictional force • Centripetal Force / Centrifugal Force • Electrostatic force • Elastic force • Work of a force • Power • Kinetic and potential energy • Kinetic energy theorem • Potential energy theorem • Conservative and non-conservative forces • Principle of conservation of mechanical energy • Definition of yield Static • Moment of a force with respect to a point • Rotational balance • Stable, unstable, indifferent equilibrium • Simple machines: levers and pulleys CALORIMETRY • Physical quantities that characterize a thermodynamic system: pressure, volume, temperature • Thermometric scales • Heat • Phase transitions • Ideal gas law • Thermal expansion • Latent heat • Heat transfer FLUIDS • Hydrostatic • Pressure • Pascal's principle • Stevino's law • Archimedes' principle Hydrodynamics • Law of continuity • Bernoulli's theorem • Venturi effect • Poiseuille equation ELECTROSTATICS • Coulomb's force • Electric field • Electric potential • Electric current • Ohm's Laws • Elementary electrical circuit: resistors in series and in parallel
(reference books)
Douglas C. Giancoli “PHYSICS: Principles with Applications” Seventh edition or subsequent, Pearson Education. Inc
Additional material will be provided by the instructor.
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Module: Biochemistry
(objectives)
The purpose of teaching is to provide students with the knowledge necessary for the performance of their future work. In particular, the comprehension of the physical principles underlying medical physics and the operation of medical instrumentation will be addressed. By the end of the course, students will know the basic concepts of applying the Scientific Method to the study of biomedical phenomena (choice and measurement of parameters, evaluation of errors). They will be able to describe physical phenomena of complex systems using appropriate mathematical tools, they will know the scientific basis of medical procedures and the principles of operation of equipment commonly used for diagnostics and therapy. They will acquire basic knowledge about the structure and function of biological macromolecules (carbohydrates, lipids, amino acids and proteins); basic knowledge about the main metabolic pathways and cycles with special emphasis on glucose, lipid and amino acid metabolism; knowledge about the morphological and physiological characteristics of the cell as a functional unit of living organisms. Another important objective will be the application of the experimental method as a means of understanding the biological mechanisms that regulate life and a tool for the study of pathological processes. At the end of the course the student will also be able to distinguish the main classes of genetic, monogenic, chromosomal and multifactorial diseases and recognize their modes of transmission.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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BIO/10
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Contact Hours
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14
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Type of Activity
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Basic compulsory activities
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Teacher
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Nicolai Eleonora
(syllabus)
• Fundamental and derived physical quantities • Dimensional equations • Scientific Notation • Orders of Greatness • Scalar and vector quantities • Vectors Mechanics • Kinematics • Uniform rectilinear motion • Rectilinear motion uniformly accelerated • Graphic representation of the motions • Uniform circular motion Dynamics • Fundamental forces • Principles of dynamics: Newton's I, II, III law • Translational equilibrium • Inertial and non-inertial reference systems • Inertial mass concept • Gravitational force • Strength weight • Normal force to the supporting surface • Tension of a rope • Frictional force • Centripetal Force / Centrifugal Force • Electrostatic force • Elastic force • Work of a force • Power • Kinetic and potential energy • Kinetic energy theorem • Potential energy theorem • Conservative and non-conservative forces • Principle of conservation of mechanical energy • Definition of yield Static • Moment of a force with respect to a point • Rotational balance • Stable, unstable, indifferent equilibrium • Simple machines: levers and pulleys CALORIMETRY • Physical quantities that characterize a thermodynamic system: pressure, volume, temperature • Thermometric scales • Heat • Phase transitions • Ideal gas law • Thermal expansion • Latent heat • Heat transfer FLUIDS • Hydrostatic • Pressure • Pascal's principle • Stevino's law • Archimedes' principle Hydrodynamics • Law of continuity • Bernoulli's theorem • Venturi effect • Poiseuille equation ELECTROSTATICS • Coulomb's force • Electric field • Electric potential • Electric current • Ohm's Laws • Elementary electrical circuit: resistors in series and in parallel
(reference books)
Douglas C. Giancoli “PHYSICS: Principles with Applications” Seventh edition or subsequent, Pearson Education. Inc
Additional material will be provided by the instructor.
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Module: Medical Genetics
(objectives)
The purpose of teaching is to provide students with the knowledge necessary for the performance of their future work. In particular, the comprehension of the physical principles underlying medical physics and the operation of medical instrumentation will be addressed. By the end of the course, students will know the basic concepts of applying the Scientific Method to the study of biomedical phenomena (choice and measurement of parameters, evaluation of errors). They will be able to describe physical phenomena of complex systems using appropriate mathematical tools, they will know the scientific basis of medical procedures and the principles of operation of equipment commonly used for diagnostics and therapy. They will acquire basic knowledge about the structure and function of biological macromolecules (carbohydrates, lipids, amino acids and proteins); basic knowledge about the main metabolic pathways and cycles with special emphasis on glucose, lipid and amino acid metabolism; knowledge about the morphological and physiological characteristics of the cell as a functional unit of living organisms. Another important objective will be the application of the experimental method as a means of understanding the biological mechanisms that regulate life and a tool for the study of pathological processes. At the end of the course the student will also be able to distinguish the main classes of genetic, monogenic, chromosomal and multifactorial diseases and recognize their modes of transmission.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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MED/03
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Contact Hours
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14
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Type of Activity
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Basic compulsory activities
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Teacher
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D'Apice Maria Rosaria
(syllabus)
• Basic Genetics: Definitions of Key Terms: gene, locus, allele, genotype, phenotype, haplotype, homozygous, heterozygous, haploid, diploid, dominance, recessivity, mutation, polymorphism. • Principles of Genetic Transmission: Segregation in Human Pedigrees. • Monogenic Inheritance Models: Autosomal inheritance, Autosomal recessive inheritance, X-linked inheritance • Genetic Risk calculation and pedigrees • Chromosomes: Structure and Analysis, Chromosomes Pathologies • Genomic Imprinting • X-chromosome inactivation • Mitochondrial inheritance: mitochondrial DNA, pattern of inheritance • Multifactorial inheritance: polymorphisms, susceptibility genes, gene-environment interaction, association studies • Pharmacogenomics and Personalised Medicine • Genetic tests and Counselling
(reference books)
“Medical Genetics” by Lynn Jorde John Carey Michael Bamshad. Edited by Elsevier
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Module: Applied Biology
(objectives)
The purpose of teaching is to provide students with the knowledge necessary for the performance of their future work. In particular, the comprehension of the physical principles underlying medical physics and the operation of medical instrumentation will be addressed. By the end of the course, students will know the basic concepts of applying the Scientific Method to the study of biomedical phenomena (choice and measurement of parameters, evaluation of errors). They will be able to describe physical phenomena of complex systems using appropriate mathematical tools, they will know the scientific basis of medical procedures and the principles of operation of equipment commonly used for diagnostics and therapy. They will acquire basic knowledge about the structure and function of biological macromolecules (carbohydrates, lipids, amino acids and proteins); basic knowledge about the main metabolic pathways and cycles with special emphasis on glucose, lipid and amino acid metabolism; knowledge about the morphological and physiological characteristics of the cell as a functional unit of living organisms. Another important objective will be the application of the experimental method as a means of understanding the biological mechanisms that regulate life and a tool for the study of pathological processes. At the end of the course the student will also be able to distinguish the main classes of genetic, monogenic, chromosomal and multifactorial diseases and recognize their modes of transmission.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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BIO/13
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Contact Hours
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14
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Type of Activity
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Basic compulsory activities
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Teacher
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Pacini Laura
(syllabus)
APPLIED BIOLOGY Characteristics of living organisms, levels of organization and classification principles. Macromolecules structure, shape and function: carbohydrates, lipids, proteins and nucleic acids. The cell as the basic unit of life, Cell Theory. Prokaryotic and eukaryotic cells. Structure and function of the eukaryotic cell: plasma membrane, cytoplasm, ribosomes, smooth and rough endoplasmic reticulum, Golgi apparatus, lysosomes, peroxisomes, cytoskeleton. Relationship between energy conversion processes and cellular structures, mitochondria and chloroplasts (notes). Nucleus. Nuclear envelope, nucleoli, chromatin and chromosomes. Molecular bases of hereditary information. DNA structure and function. Gene expression: transcription and maturation of transcripts. Genetic code and translation. Main post-translational modifications and post-synthetic fate of proteins. Endomembranes and vesicular trafficking. Exocytosis and Endocytosis. Cell cycle, Mitosis and meiosis.
APPLIED PHYSICS - Fundamental and derived physical quantities - Dimensional equations - Scientific Notation - Orders of Greatness - Scalar and vector quantities - Vectors Mechanics - Kinematics - Uniform rectilinear motion - Rectilinear motion uniformly accelerated - Graphic representation of the motions - Uniform circular motion Dynamics - Fundamental forces - Principles of dynamics: Newton's I, II, III law - Translational equilibrium - Inertial and non-inertial reference systems - Inertial mass concept - Gravitational force - Strength weight - Normal force to the supporting surface - Tension of a rope - Frictional force - Centripetal Force / Centrifugal Force - Electrostatic force - Elastic force - Work of a force - Power - Kinetic and potential energy - Kinetic energy theorem - Potential energy theorem - Conservative and non-conservative forces - Principle of conservation of mechanical energy - Definition of yield Static - Moment of a force with respect to a point - Rotational balance - Stable, unstable, indifferent equilibrium - Simple machines: levers and pulleys CALORIMETRY - Physical quantities that characterize a thermodynamic system: pressure, volume, temperature - Thermometric scales - Heat - Phase transitions - Ideal gas law - Thermal expansion - Latent heat - Heat transfer FLUIDS - Hydrostatic - Pressure - Pascal's principle - Stevino's law - Archimedes' principle Hydrodynamics - Law of continuity - Bernoulli's theorem - Venturi effect - Poiseuille equation ELECTROSTATICS - Coulomb's force - Electric field - Electric potential - Electric current - Ohm's Laws - Elementary electrical circuit: resistors in series and in parallel
BIOCHEMISTRY - Short summary of basic concepts of inorganic and organic chemistry - Chemical bonds, osmotic pressure, pH, buffers. The constituents of biological macromolecules: carbohydrates, lipids, purines, pyrimidines, nucleosides, nucleotides, amino acids. Proteins structure and function. Hemoproteins and gas transport (O2, CO2). Coenzymes and vitamins. Enzymes. Introduction to metabolism. Catabolism and anabolism. Glucose catabolism: glycolysis and the Kreb’s cycle. Catabolism of fatty acids. The mitochondrion as the power plant of the cell: oxidative phosphorylation. Hormonal control of glucose metabolism. Insulin and glucagon: glycogenolysis, glycogen synthesis, gluconeogenesis and lipolysis. Fasting, diabetes and ketogenesis. Biosynthesis of fatty acids and phospholipids. Cholesterol metabolism. Amino acid metabolism and urea cycle in brief.
MEDICAL GENETICS Basic Genetics: Definitions of Key Terms: gene, locus, allele, genotype, phenotype, haplotype, homozygous, heterozygous, haploid, diploid, dominance, recessivity, mutation, polymorphism. Principles of Genetic Transmission: Segregation in Human Pedigrees. Monogenic Inheritance Models: Autosomal inheritance, Autosomal recessive inheritance, X-linked inheritance Genetic Risk calculation and pedigrees Chromosomes: Structure and Analysis, Chromosomes Pathologies Genomic Imprinting X-chromosome inactivation Mitochondrial inheritance: mitochondrial DNA, pattern of inheritance Multifactorial inheritance: polymorphisms, susceptibility genes, gene-environment interaction, association studies Pharmacogenomics and Personalised Medicine Genetic tests and Counselling
(reference books)
• Douglas C. Giancoli “PHYSICS: Principles with Applications” Seventh edition or subsequent, Pearson Education. Inc • Ashok Kumar J. “Textbook of Biochemistry for Nurses” II edition – 2012. I K International Publishing House • “Medical Genetics” by Lynn Jorde John Carey Michael Bamshad. Edited by Elsevier • Sadava, Hillis, Heller, Hacker. Elementi di Biologia e Genetica Zanichelli editore, V ed. • Curtis, Barnes, Schnek, Massarini. Elementi di Biologia. Zanichelli editore I ed. • Raven,Johnson, Mason, Losos, Singer. Elementi di Biologia e Genetica Piccin editore II ed.
The indicated textbook is just a reference. Students are allowed to adopt the book/books of their choice. Additional material will be provided by the instructor.
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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