Clinical biochemistry and pharmaceuticals toxicology
(objectives)
The educational objectives of the module Special Clinical Biochemistry are aimed at acquiring knowledge of the main methodologies used in clinical biochemistry, understanding the significance of alterations in biochemical-clinical relevant profiles. The module Pharmaceutical Toxicology and galenic Pharmacology aims at acquiring the fundamental principles of pharmacokinetics, pharmacodynamics, toxicology and galenic pharmacology, that underlie the execution of biochemical and pharmacogenetic tests carried out in the analysis and research laboratories, and the theoretical bases for the preparation of galenic drugs. The students must know the scientific rigor and methodological approach underlying the development of new drugs, and have to learn the fundamental aspects connected with the therapeutic use of the most frequently used classes of drugs. These objectives will be achieved through lectures, seminars and interactive teaching activities, designed to facilitate learning and improve the ability to address and resolve the main questions of the pharmaceutical industry, toxicology and pharmaceutical galenics.
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Code
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90334 |
Language
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ITA |
Type of certificate
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Profit certificate
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Module: Special clinical biochemistry
(objectives)
The educational objectives of the module of Special Clinical Biochemistry are aimed at acquiring knowledge of the main methodologies used in clinical biochemistry; understanding the significance of alterations in biochemical-clinical relevant profiles.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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2
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Scientific Disciplinary Sector Code
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BIO/12
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Contact Hours
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20
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Type of Activity
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Core compulsory activities
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Teacher
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Montagna Costanza
(syllabus)
From biological sample collection to reporting Pre-pre-analytical phase, pre-analytical phase, analytical phase, post-analytical phase, interpretation of results. Analytical groupings Blood, urine, feces, CSF, hair, and saliva. Profiles of biochemical-clinical significance Glucose profile, protein profile, lipid profile, profile. vitamin profile.
(reference books)
Biochimica clinica essenziale, dal laboratorio ai quadri di patologia clinica. Elisabetta Albi Tommaso Beccari Samuela Cataldi. Zanichelli 2019.
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
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Module: Pharmaceutical toxicology and galenic pharmacology
(objectives)
The module aims at acquiring the fundamental principles of pharmacokinetics, pharmacodynamics, toxicology and galenic pharmacology, that underlie the execution of biochemical and pharmacogenetic tests carried out in the analysis and research laboratories, and the theoretical bases for the preparation of galenic drugs. The students must know the scientific rigor and methodological approach underlying the development of new drugs. They will also have to learn the fundamental aspects connected with the therapeutic use of the most frequently used classes of drugs. These objectives will be achieved through lectures, seminars and interactive teaching activities, designed to facilitate learning and improve the ability to address and resolve the main questions of the pharmaceutical industry, toxicology and pharmaceutical galenics.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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3
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Scientific Disciplinary Sector Code
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BIO/14
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Contact Hours
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30
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Type of Activity
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Basic compulsory activities
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Teacher
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Ceci Claudia
(syllabus)
Pharmaceutical Toxicology and galenic Pharmacology Syllabus. Definition of drug; drugs classification and nomenclature; desired and undesired effects of drugs General principles of pharmacodynamics: receptors and mechanism of action of drugs Development of new drugs: general principles of in vitro drug sensitivity tests; preclinical studies and clinical trials General principles of pharmacokinetics: routes of drug administration, absorption, distribution, metabolism, elimination of drugs. Pharmacogenomics: individual variability of drug response, variation of target proteins, variation in enzymes responsible for drug metabolism. Autonomic pharmacology (parasympathomimetics and cholinergic antagonists; sympathomimetics and adrenergic antagonists) Special pharmacology; general characteristics of the following classes of drugs: antiinflammatory drugs, opioids, antirheumatic drugs (traditional and biological DMARDs), antimicrobial agents, anticancer agents (antimitotics and antimetabolites), gastrointestinal pharmacology, pulmonary pharmacology, endocrine pharmacology. Principles of toxicology; toxicokinetics; toxication and detoxification mechanisms; main sources of toxicity; toxic drug effects. Principles of pharmaceutical galenic, magisterial and officinal galenic, auxiliary substances in galenic preparations: solvents, excipients, preservatives.
(reference books)
1) Di Giulio et al. Farmacologia generale e speciale per le lauree sanitarie. Piccin, second edition. 2) Clementi F., Fumagalli G. FARMACOLOGIA GENERALE E MOLECOLARE. 5th edition EDRA, 2018. 3) C. Colombo, F. Alhaique, C. Caramella, B. Conti, A. Gazzaniga, E. Vidale. Principi di Tecnologia Farmaceutica. Zanichelli 2015. 4) Other material and scientific articles indicated by the teacher
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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