Clinical biochemistry, clinical molecular biology and applied statistics
(objectives)
For the course of Clinical Biochemistry and Clinical Molecular Biology, knowledge of traditional and innovative methodologies used in the laboratory for the determination of different proteins in the clinical biochemistry laboratory are essential objectives. These objectives will be achieved through lectures and with interactive teaching activities, associated with facilitating learning and improving the ability to face and solve the main diagnostic questions of the clinical biochemistry laboratory. The course aims to provide the student with the skills necessary to understand the role played by information systems and database management systems, illustrating the development process. It is an essential goal of the Statistics course for Experimental research to learn the knowledge of the essential elements for the interpretation of the accuracy and predictive values of a diagnostic test. This course will also deal with issues relating to the comparison of tests and the fundamental aspects of study designs for biomedical research for diagnostics. These objectives will be achieved through lectures and practical examples illustrating the methodology of some scientific studies published in the medical literature. Knowledge of the methods for selecting and managing independently the analytical processes for the various analysis techniques, applying laboratory safety principles and biomedical laboratory activities as an entity represent internal health system. The main educational objectives of the clinical biochemistry course are acquired by the student of basic knowledge on the clinical-diagnostic significance of some of the laboratory tests that control the "chemical-clinical profile". These objectives will be achieved through lectures and with interactive teaching activities, associated with facilitating learning and improving the ability to face and solve the main diagnostic questions of the clinical biochemistry laboratory. At the end of the course, students will know the fundamental concepts of the application of the scientific method to the study of biomedical phenomena, the scientific bases of medical procedures and the principles of operation of the equipment used for diagnostics and therapy, as well as supplying the student with the skills provided understanding the key role that Information Technology (IT) plays for today's society and, in particular, required by the technical-health professions.
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Code
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90330 |
Language
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ITA |
Type of certificate
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Profit certificate
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Module: Clinical biochemistry and clinical molecular biology
(objectives)
The knowledge of traditional and innovative methods for the determination of different proteins in the clinical biochemistry and molecular biology laboratory are essential goals. These objectives will be achieved through lectures and interactive educational activities designed to facilitate learning and improve the ability to face and solve the main ones diagnostic questions from the clinical biochemistry laboratory.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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2
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Scientific Disciplinary Sector Code
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BIO/12
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Contact Hours
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20
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Type of Activity
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Core compulsory activities
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Teacher
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Pieri Massimo
(syllabus)
Proteins: functions in all biological liquids and methods of determination. Clinical biochemistry of the liver and kidney. Glucose Homeostasis. The emergency laboratory. Heart markers and drugs of abuse. Clinical biochemistry of cerebrospinal fluid. DNA sequencing techniques.
(reference books)
The student will be provided with educational material, such as notes and presentations.
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Module: Data processing systems
(objectives)
The course intends to provide students with the basic knowledge to understand the role of Information Systems and Database Management Systems, focusing also on their lifecycle.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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ING-INF/05
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Contact Hours
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10
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Type of Activity
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Core compulsory activities
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Teacher
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Bocciarelli Paolo
(syllabus)
ntroduction to Information Systems Information System types The lifecycle of Information Systems Overview of Database and Database Management System (DBMS)
(reference books)
Deborah Morley and Charles S. Parker, Understanding Computers: Today and Tomorrow (16th edition) - Cengage Learning
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Module: Experimental research statistics
(objectives)
The knowledge of the basic elements for the interpretation of the accuracy of a laboratory test (sensitivity, specificity, negative predictive value and positive predictive value) will be an essential learning objective. The course will also address issues related to tests comparison and study design for biomedical research; including: diagnostic cohort studies, case control studies for accuracy, studies for paired measures and randomized studies. These goals will be achieved through face-to-face lectures and practical examples through guided analysis of studies published in peer-reviewed medical literature.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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SECS-S/02
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Contact Hours
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10
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Type of Activity
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Core compulsory activities
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Teacher
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Lanini Simone
(syllabus)
• Diagnostic accuracy: sesistivity, specificity and pre-test probability • Predictive values: negative predictive values, positive predictive values and prevalence • Positive likelihood and negative likelihood • Bayes theorem • Gold Standard, Reference Tests and Index Tests • Target population, study population, target situation and target condition • McNemar test • Diagnostic cohort studies • Case control study for research in diagnostics medicine • Paired comparative studies for research in diagnostics medicine • Clinical outcome studies (benefit studies)
(reference books)
The Design of Diagnostic Studies - Reading material for an internetbased course Werner Vach, Veronika Reiser, Izabela Kolankowska, Susanne Weber Copyright University of Freiburg, 2014 https://www.offenehochschule.uni-freiburg.de/ordner/data/doc/knowledge_translation/dokumentation-diagnosekurs
Margaret Sullivan Pepe The Statistical Evaluation of Medical Tests for Classification and Prediction (Oxford Statistical Science Series) 1st Edition ISBN-13: 978-0198565826 ISBN-10: 0198565828
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Module: Technical sciences of laboratory medicine
(objectives)
The knowledge of the methods for selecting and managing represent specific training objectives independently the analytical processes for the different analysis techniques, apply the safety principles of laboratory and organization of biomedical laboratory activities as an entity within thesanitary system.The main educational objectives of the clinical biochemistry course are the acquisition by the student of basic knowledge on the clinical-diagnostic significance of some of the laboratory tests that form the "chemical-clinical profile".These objectives will be achieved through lectures and interactive educational activities, designed to facilitate learning and improve the ability to deal with and resolve the main ones diagnostic questions from the clinical biochemistry laboratory
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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2
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Scientific Disciplinary Sector Code
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MED/46
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Contact Hours
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20
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Type of Activity
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Core compulsory activities
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Teacher
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Cabrini Alessia
(syllabus)
Pre-analytical variability (treatment and conservation of biological materials). The laboratory error. General characteristics of measurement techniques. The techniques of separation of biological material. The main measurement techniques used in a clinical chemistry laboratory (photometry, spectrophotometry, chromatography, fluorimetry, turbidimetry, nephelometry, electrophoresis and signs of serology) Laboratory investigations of carbohydrate, lipid and nitrogen metabolism Hematologic parameters: glycaemia, hemoglobin, glycated hemoglobin, lipidemia, bilirubin, azote-mia, uricemia, transaminase. Principles and Techniques of Hematology and Coagulation. molecular investigations, application of PCR in clinical biochemistry
(reference books)
The student will be provided with educational material, such as notes and presentations
|
Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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