Biology, applied physics, biochemistry
(objectives)
At the end of the course, the students will know the fundamental concepts of application of the Scientific Method to the study of biomedical phenomena (choice and measure of parameters, evaluation of errors), they will be able to describe physical phenomena of complex systems using suitable mathematical tools, they will know the scientific basis of medical procedures and principles of functioning of the equipment commonly used for diagnostics and therapeutics. Students will learn knowledge on the structure, function, and regulation of biological macromolecules (carbohydrates, lipids, amino acids and proteins). To acquire basic knowledge on the main metabolic pathways and cycles with particular regard to carbohydrate, lipid and amino acid metabolism. Students will learn with knowledge on the main notions on inheritance of monogenic, chromosomal and multifactorial diseases. At the end of the course the student will be able to distinguish the main classes of genetic diseases and to recognize the modes of transmission of hereditary diseases. Students will learn knowledge related to the physiological and morphological characteristics of cells, as functional units of living organisms. Another important goal is to utilize the experimental method to understand the biological mechanisms that regulate life and as a tool for the study of pathological processes.
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Code
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90348 |
Language
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ITA |
Type of certificate
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Profit certificate
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Module: Biochemistry
(objectives)
Aim of the teaching is to provide students with knowledge on the fundamentals of applied physics, biochemistry, medical genetics and biology necessary to the performance of their future activity. At the end of the course, the students will know the fundamental concepts of application of the Scientific Method to the study of biomedical phenomena (choice and measure of parameters, evaluation of errors), they will be able to describe physical phenomena of complex systems using suitable mathematical tools, they will know the scientific basis of medical procedures and principles of functioning of the equipment commonly used for diagnostics and therapeutics. Students will learn knowledge on the structure, function, and regulation of biological macromolecules (carbohydrates, lipids, amino acids and proteins). To acquire basic knowledge on the main metabolic pathways and cycles with particular regard to carbohydrate, lipid and amino acid metabolism. Students will learn with knowledge on the main notions on inheritance of monogenic, chromosomal and multifactorial diseases. At the end of the course the student will be able to distinguish the main classes of genetic diseases and to recognize the modes of transmission of hereditary diseases. Students will learn knowledge related to the physiological and morphological characteristics of cells, as functional units of living organisms. Another important goal is to utilize the experimental method to understand the biological mechanisms that regulate life and as a tool for the study of pathological processes.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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BIO/10
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Contact Hours
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14
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Type of Activity
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Basic compulsory activities
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Teacher
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Naviglio Silvio
(syllabus)
• Short summary of basic concepts of inorganic and organic chemistry • Chemical bonds, osmotic pressure, pH, buffers. The constituents of biological macromolecules: carbohydrates, lipids, purines, pyrimidines, nucleosides, nucleotides, amino acids. • Proteins - structure and function. Hemoproteins and gas transport (O2, CO2). Coenzymes and vitamins. Enzymes. • Introduction to metabolism. Catabolism and anabolism. Glucose catabolism: glycolysis and the Kreb’s cycle. Catabolism of fatty acids. • The mitochondrion as the power plant of the cell: oxidative phosphorylation. • Hormonal control of glucose metabolism. Insulin and glucagon: glycogenolysis, glycogen synthesis, gluconeogenesis and lipolysis. • Fasting, diabetes and ketogenesis. Biosynthesis of fatty acids and phospholipids. Cholesterol metabolism. Amino acid metabolism and urea cycle in brief.
(reference books)
David L Nelson Michael M Cox. I principi di biochimica di Lehninger. Ed. Zanichelli
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Module: Medical genetics
(objectives)
Aim of the teaching is to provide students with knowledge on the fundamentals of applied physics, biochemistry, medical genetics and biology necessary to the performance of their future activity. At the end of the course, the students will know the fundamental concepts of application of the Scientific Method to the study of biomedical phenomena (choice and measure of parameters, evaluation of errors), they will be able to describe physical phenomena of complex systems using suitable mathematical tools, they will know the scientific basis of medical procedures and principles of functioning of the equipment commonly used for diagnostics and therapeutics. Students will learn knowledge on the structure, function, and regulation of biological macromolecules (carbohydrates, lipids, amino acids and proteins). To acquire basic knowledge on the main metabolic pathways and cycles with particular regard to carbohydrate, lipid and amino acid metabolism. Students will learn with knowledge on the main notions on inheritance of monogenic, chromosomal and multifactorial diseases. At the end of the course the student will be able to distinguish the main classes of genetic diseases and to recognize the modes of transmission of hereditary diseases. Students will learn knowledge related to the physiological and morphological characteristics of cells, as functional units of living organisms. Another important goal is to utilize the experimental method to understand the biological mechanisms that regulate life and as a tool for the study of pathological processes.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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MED/03
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Contact Hours
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14
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Type of Activity
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Basic compulsory activities
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Teacher
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Ciccacci Cinzia
(syllabus)
• Basic Genetics: Definitions of Key Terms: gene, locus, allele, genotype, phenotype, haplotype, homozygous, heterozygous, haploid, diploid, dominance, recessivity, codominance, mutation, polymorphism. • Principles of Genetic Transmission: Mendel's Genetic Hypothesis, The Monohybrid and Dihybrid Crosses, Segregation in Human Pedigrees, Blood groups Genetics • Monogenic Inheritance Models: Autosomal inheritance, Autosomal recessive inheritance, X-linked inheritance • Genetic Risk calculation and pedigrees • Chromosomes: Structure and Analysis, Chromosomes Pathologies • Genomic Imprinting • X-chromosome inactivation • Mitochondrial inheritance: mitochondrial DNA, pattern of inheritance • Multifactorial inheritance: polimorphisms, susceptibility genes, gene-environment interaction, association studies • Pharmacogenomics and Personalised Medicine • Genetic tests and Counselling
(reference books)
“Genetica in Medicina”, by Nussbaum, McInnes, Willard. Edises; “Genetica Medica Essenziale” by Dallapiccola, Novelli. Cic editore
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Module: Applied physics
(objectives)
Aim of the teaching is to provide students with knowledge on the fundamentals of applied physics, biochemistry, medical genetics and biology necessary to the performance of their future activity. At the end of the course, the students will know the fundamental concepts of application of the Scientific Method to the study of biomedical phenomena (choice and measure of parameters, evaluation of errors), they will be able to describe physical phenomena of complex systems using suitable mathematical tools, they will know the scientific basis of medical procedures and principles of functioning of the equipment commonly used for diagnostics and therapeutics. Students will learn knowledge on the structure, function, and regulation of biological macromolecules (carbohydrates, lipids, amino acids and proteins). To acquire basic knowledge on the main metabolic pathways and cycles with particular regard to carbohydrate, lipid and amino acid metabolism. Students will learn with knowledge on the main notions on inheritance of monogenic, chromosomal and multifactorial diseases. At the end of the course the student will be able to distinguish the main classes of genetic diseases and to recognize the modes of transmission of hereditary diseases. Students will learn knowledge related to the physiological and morphological characteristics of cells, as functional units of living organisms. Another important goal is to utilize the experimental method to understand the biological mechanisms that regulate life and as a tool for the study of pathological processes.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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FIS/07
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Contact Hours
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14
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Type of Activity
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Basic compulsory activities
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Teacher
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Guerrisi MariaGiovanna
(syllabus)
PHYSICAL QUANTITIES: Operational concept of physical quantity. Fundamental and derivative quantities. Scalar and vector quantities. Systems of measurement units. Measurement of physical quantities. Systematic errors and accidental errors. Sensitivity, precision of a measuring instrument. MOVEMENT: Velocity and acceleration as scalar quantities. Velocity and acceleration as vectors. THE FORCES: The concept of strength and the principle of inertia. The concept of mass is the second principle of dynamics. The weight force is the acceleration of gravity. The third principle of dynamics. Static balance of a material point. Balancing of a system of forces. Friction. Rigid bodies and center of gravity. Moment of a force with respect to a point. Balance of a rigid body. Definition and equilibrium condition of a lever. Various types of leverage. Levers in the human body. WORK AND ENERGY: Work of a force. Work and kinetic energy. The concept of energy. Conservative forces (outline). Potential energy. LIQUIDS: Definition and unit of measurement of pressure. Density and specific weight. Forces acting on a volume of fluid at rest. Stevino Law. Pressure gauges. Pascal's law. THERMOMETRY and GAS: The concept of temperature. The centigrade temperature scale. Expansion thermometers. Clinical thermometer. Absolute temperature scale. The equation of state of perfect gases. HEAT AND INTERNAL ENERGY: The concept of quantity of heat. Heat measurement unit. Thermal capacity of a body and specific heat of a substance. Expression of the amount of heat exchanged by a body. The internal energy of a system. The first principle of thermodynamics. Thermodynamic transformations. State changes. Metabolic power. Energy value of food. Temperature control SOUND: wave phenomena. Elastic and electromagnetic waves. Nature of sound. Wavelength. Sound intensity. Technical applications and biological effects of ultrasound. Ultrasound in medical diagnostics. THE ELECTRICAL PHENOMENA: The electric charge. Conductors and insulators. Electric field and intensity of the electric field. Coulomb law. Unit of measurement of electric charges. Dielectric constant. Electrical potential and potential difference. Electric capacitors. Electric current and current intensity. The direct current. Energy considerations on electrical circuits. Ohm's law. Electrical resistance and resistivity. Resistance in series and in parallel. Internal resistance of a generator. The thermal energy connected with the Joule effect. Power absorbed by a device. Electrical Safety IONIZING RADIATION: Introduction to radiation. Radiation, radioactive decay, law of radioactive decay. Biological half-life. The most common decays and associated radiation. Interaction of radiation with matter and hints of dosimetry
(reference books)
Gian Marco Contessa- Giuseppe Augusto Marzo; Fisica applicata alle scienze mediche- Casa Editrice Ambrosiano Ezio Ragozzino, Elementi di Fisica per studenti di Scienze Biomediche –EdiSES - 2 ediz. Paul Davidovits: Fisica per le professioni sanitarie- UTET.
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Module: Applied biology
(objectives)
Aim of the teaching is to provide students with knowledge on the fundamentals of applied physics, biochemistry, medical genetics and biology necessary to the performance of their future activity. At the end of the course, the students will know the fundamental concepts of application of the Scientific Method to the study of biomedical phenomena (choice and measure of parameters, evaluation of errors), they will be able to describe physical phenomena of complex systems using suitable mathematical tools, they will know the scientific basis of medical procedures and principles of functioning of the equipment commonly used for diagnostics and therapeutics. Students will learn knowledge on the structure, function, and regulation of biological macromolecules (carbohydrates, lipids, amino acids and proteins). To acquire basic knowledge on the main metabolic pathways and cycles with particular regard to carbohydrate, lipid and amino acid metabolism. Students will learn with knowledge on the main notions on inheritance of monogenic, chromosomal and multifactorial diseases. At the end of the course the student will be able to distinguish the main classes of genetic diseases and to recognize the modes of transmission of hereditary diseases. Students will learn knowledge related to the physiological and morphological characteristics of cells, as functional units of living organisms. Another important goal is to utilize the experimental method to understand the biological mechanisms that regulate life and as a tool for the study of pathological processes.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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BIO/13
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Contact Hours
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14
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Type of Activity
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Basic compulsory activities
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Teacher
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Pacini Laura
(syllabus)
• Characteristics of living organisms, levels of organization and principles of classification. • Macromolecules of biological interest: carbohydrates, lipids, elements of structure and function of proteins and nucleic acids. • The cell as the basic unit of life, Cell Theory. Prokaryotic and eukaryotic cells, organization and differences. Endosymbiontic theory. Notes on viruses. • Structure and function of the eukaryotic cell: plasma membrane, cytoplasm, ribosomes, smooth and rough endoplasmic reticulum, Golgi apparatus, lysosomes, peroxisomes, cytoskeleton. • Notes on relationship between energy conversion processes and cellular structures, mitochondria and chloroplasts. • The nucleus: Nuclear envelope, nucleoli, chromatin and chromosomes. • Molecular basis of hereditary information. DNA structure and function. • Gene expression: transcription and maturation of primary transcripts. • Genetic code and translation. Reading and interpretation of the genetic code, protein synthesis, major post-translational modifications and post-synthetic fate of proteins. • Endomembranes and vesicular trafficking. Exocytosis and Endocytosis. • Cell cycle, mitosis and meiosis.
(reference books)
Sadava D, M. Hillis D, Craig Heller H, Hacker S, "Elementi di Biologia e genetica"¸ Zanichelli, V ed. Raven P H, Johnson G B, Mason K A “Elementi di Biologia e Genetica” Piccin, II ed.
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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