Among the aims of the course, there is the understanding of hematopoietic and lymphoid system and its physiopathological disorders. Futhermore, knowledge of the main haematological disorders is also required, such as anemia and clonal hematopoiesis (ARCH, CHIP, ICUS CCUS and IDUS), as well as, oncohematological disorders such as myelodysplastic syndromes, acute and chronic myeloid leukemias, myeloproliferative disorders, lymphoblastic leukemia and lymphoma.
In addition, students will know the main non communicable diseases and the basis of clinical methodology.
Moreover, the aim of the lessons is to give the students the ability to recognize the clinical presentation, epidemiology, course and prognosis of main rheumatic diseases.
Another aim of the course is to provide students the knowledge of microorganism-host interactions and the clinical situations, including infections, infectious diseases, colonization, deriving from this interaction. This course will give also the basics for applying proper diagnostic procedures to identify the presence of microorganisms and their role towards the host. Moreover, the course will introduce the pharmacological properties of the main anti-infective substances, and the proper treatment of the infectious diseases.
During the course, the teacher will introduce the main diseases with an infective etiology, giving the students elements of epidemiology, pathophysiology, differential and laboratory diagnosis, and clinical-therapeutical management. A particular overview of emerging and re-emerging infections will be treated. At the end of the course, the student will also know the principles of the control and prevention of infections in the community and healthcare settings, in a “One Health” approach.

LEARNING OUTCOMES

Knowledge and understanding

At the end of the course the student will be able to:
• Recognize the main components of the hematopoietic system
• Distinguish the main disorders affecting the lymphohematopoietic system
• Identify the main causes of haematological and oncohematological disorders
• Manage the differential diagnosis of the main hematological and oncohematological disorders
• Know the main therapeutic strategies for the management of the haematological patient
• Know and explain the basis of clinical methodology
• Know and explain the global burden of diseases
• Know and explain cardiovascular diseases
• Know and explain the basis of the stroke
• Know and explain Pulmonary Obstructive Disease (COPD)
• Know and explain Diabetes.
• Discuss the pathophysiology of the main rheumatic diseases, and their distinctive clinical picture Identify the indications for laboratory tests and interpret the results
• Access and evaluate medical information relevant to the topics objects of this course.
• Know the classification of the main bacterial, viral and protozoan infections
• Describe the epidemiological principles of diseases, with special attention to the different geographical contexts, including the epidemiological chain of transmission
• Describe the differences between contaminations, colonization, infection, infectious disease
• Know the most common community acquired infectious diseases
• Know the most common healthcare associated infectious diseases
• Describe the elements for the prevention and control of infection, and the principles of the antimicrobial stewardship
• Know the most important infections in the immunocompromised patient (HIV and non-HIV)
• Know the emerging and re-emerging infectious diseases
• Understand the diagnostics for pathogens and immune response
• Know and describe the main therapeutic classes for prevention and treatment
• Describe isolation and infection control measures

Applying knowledge and understanding
At the end of the course the student will be able to:

• Use the knowledge acquired for the in-depth study of aspects relating to the specific field to which the student will dedicate himself in the professional activity
• cooperate with other healthcare providers in making decisions regarding diagnosis, treatment, and monitoring patient’s conditions, using laboratory testings in order to improve clinical outcomes at a greatly reduced costs.
• understand and explain the risk factors and the pathophysiology of infectious diseases

Communication skills
At the end of the course the student will be able to:

• Know and correctly use proper scientific language aimed to a correct and rigorous scientific communication.
• Have knowledge of the procedures to inform patients, contacts on transmission risks; as well as health authorities for mandatory notifications of infectious diseases.


Making judgements
At the end of the course the student should be able to make general assessments of the topics covered. The student will be also able to independently develop the logical procedures that lead to a differential diagnosis and, at the same time, to critically analyze the microbiological data supporting a diagnosis.

Learning skills:
at the end of the integrated teaching, the student will acquire skills useful to deepen and expand their knowledge in the field of the course, also through the consultation of scientific literature, databases, specialized websites.