Laboratory medicine
(objectives)
The integrated teaching of Laboratory Medicine is aimed at introducing the student to the logic and tools underlying the execution of the diagnostic tests of the Clinical Biochemistry, Clinical Pathology, Clinical Microbiology, Clinical Parasitology and Rheumatology. At the end of the integrated teaching, the student will be able to apply diagnostic tests in the clinical practice, and to interpret and evaluate their results.
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Code
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90291 |
Language
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ENG |
Type of certificate
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Profit certificate
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Module: Clinical biochemistry and clinical molecular biochemistry
(objectives)
The integrated teaching of Laboratory Medicine is aimed at introducing the student to the logic and tools underlying the execution of the diagnostic tests of the Clinical Biochemistry, Clinical Pathology, Clinical Microbiology, Clinical Parasitology and Rheumatology. At the end of the integrated teaching, the student will be able to apply diagnostic tests in the clinical practice, and to interpret and evaluate their results.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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2
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Scientific Disciplinary Sector Code
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BIO/12
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Contact Hours
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20
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Type of Activity
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Core compulsory activities
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Teacher
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Barbato Gaetano
(syllabus)
Clinical biochemistry and clinical molecular biochemistry Definition, limits and scope of Laboratory Medicine; Classification of Disciplines within Laboratory Medicine. General organization of the Laborator. Rational behind laboratory test choice; strategy in requesting laboratory test (screening test, individual test, organ profiling, diagnostic protocols, therapy monitoring etc.). Statistics Basic statistics recall: Frequency distribution; Population and representative sample; Probability and Probability distribution; Population dispersion and Standard Deviation Variation Sources of Variation; impact of pre-analytical phase on variability: sample collection and transportation; impact of analytical on variability; analytical performance and indicators. Hierarchy of analytical methods; Errors. Impact of biological variation: nature of B. variation; reference values selection and use; cut-off. Use of the laboratory data: clinical performance of tests; clinical sensitivity, clinical specificity, Receiver operating characteristic (ROC) curves; Predictive value; Introduction to Quality Systems; accreditation and certification; Control of the analysis product. Use of Diagnostic Biomarkers dosage: Enzymatic Biomarkers : Enzyme’s role in clinical diagnosis. Enzyme quantification in clinical chemistry; Early markers and late markers. Enzymatic dosing methodologies: Continuous and discrete measure dosing. Substrate, Product and co-factors dosing. Diagnostic dosing “Case Studies” in the Clinical Laboratory practice as organ markers: Creatin Kinase (CK), Lactic DeHydrogenase (LDH), Transaminases (ALT, AST), -Glutamyltransferase (-GGT), Alkaline (ALP) and Acidic (ACP) Phosphatases, Amylase, Lipase. Electrolytes and Blood Gases: Colligative properties; Water Homeostasis; Specimens for Electrolyte determination; Sodium; Potassium; Chloride; Bicarbonate; Methods for determination; Electrolyte exclusion effect; Osmotic Pressure; Osmolality; determination of Plasma and Urine Osmolality; Blood gases and pH; Henderson-Hasselbalch equation in gas measurements; oxygen in blood; hemoglobin saturation/dissociation; determination of pCO2, pO2 and pH. Electrolites and water composition of body fluids; extracellular and intracellular compartments; acid-base balance and status; buffer systems and regulation of body fluids pH; respiratory and renal mechanisms in the regulation of acid-base balance; conditions associated with abnormal acid-base status or abnormal electrolyte composition of blood; Metabolic acidosis and alkalosis; respiratory acidosis and alkalosis.
(reference books)
• “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446 • Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor • Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke Second edition • Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition • Harrison’s Rheumatology, latest edition • Harrison’s Principle of Internal Medicine, latest edition • Oxford Handbook of Rheumatology, latest edition
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Module: Clinical pathology
(objectives)
The integrated teaching of Laboratory Medicine is aimed at introducing the student to the logic and tools underlying the execution of the diagnostic tests of the Clinical Biochemistry, Clinical Pathology, Clinical Microbiology, Clinical Parasitology and Rheumatology. At the end of the integrated teaching, the student will be able to apply diagnostic tests in the clinical practice, and to interpret and evaluate their results.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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2
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Scientific Disciplinary Sector Code
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MED/05
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Contact Hours
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20
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Type of Activity
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Core compulsory activities
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Teacher
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Verna Roberto
(syllabus)
• The clinical value of the laboratory. • Injury and function markers. • The blood count. • Coagulation and pathologies of the coagulation system. • Markers of inflammation and immune reactions. • Diagnosis of leukocyte pathologies. • Diagnosis of anemias. • Liver, hepatitis and cirrhosis. • Blood sugar. • Lipemia • Functional evaluation of the kidney, urinalysis. • Tumor markers. • Immunohematology and transfusion medicine. • Laboratory evaluation of drug blood concentrations, drug abuse and doping. • The laboratory in sport activities.
(reference books)
• “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446 • Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor • Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke Second edition • Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition • Harrison’s Rheumatology, latest edition • Harrison’s Principle of Internal Medicine, latest edition • Oxford Handbook of Rheumatology, latest edition
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Oral exam
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Teacher
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Barillari Giovanni
(syllabus)
• The clinical value of the laboratory. • Injury and function markers. • The blood count. • Coagulation and pathologies of the coagulation system. • Markers of inflammation and immune reactions. • Diagnosis of leukocyte pathologies. • Diagnosis of anemias. • Liver, hepatitis and cirrhosis. • Blood sugar. • Lipemia • Functional evaluation of the kidney, urinalysis. • Tumor markers. • Immunohematology and transfusion medicine. • Laboratory evaluation of drug blood concentrations, drug abuse and doping. • The laboratory in sport activities.
(reference books)
• “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446 • Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor • Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke Second edition • Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition • Harrison’s Rheumatology, latest edition • Harrison’s Principle of Internal Medicine, latest edition • Oxford Handbook of Rheumatology, latest edition
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
|
Oral exam
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Module: Microbiology and clinical microbiology
(objectives)
The integrated teaching of Laboratory Medicine is aimed at introducing the student to the logic and tools underlying the execution of the diagnostic tests of the Clinical Biochemistry, Clinical Pathology, Clinical Microbiology, Clinical Parasitology and Rheumatology. At the end of the integrated teaching, the student will be able to apply diagnostic tests in the clinical practice, and to interpret and evaluate their results.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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MED/07
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Contact Hours
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10
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Personal Study Hours
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-
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Type of Activity
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Core compulsory activities
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Credits
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1
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Scientific Disciplinary Sector Code
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MED/07
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Contact Hours
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10
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Personal Study Hours
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-
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Type of Activity
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Core compulsory activities
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Teacher
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Perno Carlo Federico
(syllabus)
• Principles of medical microbiology and immunology • Principles of diagnostic microbiology ◦ Tests used ◦ Appropriate biological samples ◦ How to get and store biological samples ◦ Interpretation of microbiological results • Elements of Diagnostic Microbiology: Direct and indirect tests, Microbial isolation, selection of the appropriate biological samples, antibiogram (Principles, purposes and interpretation) • Elements of Diagnostic Virology: Direct and indirect tests, Viral isolation, Selection of the biological samples and their preservation and storage • Elements of the diagnostic Mycology, biological isolation, selection of the biological samples; modern molecular and antigenic tests • Main etiological agents of the infections of the Nervous System; Characteristics of the cerebrospinal fluid. Samples to be used, how to get them, storage, interpretation of the results • Main etiological agents of the infections of the Upper and Lower Respiratory Tracts. Samples to be used, how to get them, storage, interpretation of the results • Main etiological agents of the infections of the Gastrointestinal System. Food-related infections. Samples to be used, how to get them, storage, interpretation of the results • Main etiological agents of the infections of the Urinary Tract. Samples to be used, how to get them, storage, interpretation of the results • Systemic infections: How to use and interpret the Haemoculture. Infections of the cardio-vascular apparatus • Main etiological agents of the infections of the Genital Tract. Infections during pregnancy. Samples to be used, how to get them, storage, interpretation of the results • Sexually transmitted diseases. Main etiological agents, samples to be used, how to get them, storage, interpretation of the results • Diagnosis of HIV and viral hepatitis • Hospital infections: Main etiological agents and their modern diagnosis. Microbiological control of the hospital infections. • Infections in the immunocompromised host; Etiological agents, Modern diagnosis, Samples used, how to get them, storage, interpretation of the results • Microbiota: Structure, clinical relevance, diagnostic methodologies • General information about the rapid diagnosis of malaria
(reference books)
• “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446 • Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor • Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke Second edition • Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition • Harrison’s Rheumatology, latest edition • Harrison’s Principle of Internal Medicine, latest edition • Oxford Handbook of Rheumatology, latest edition
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Module: Clinical parasitology
(objectives)
The integrated teaching of Laboratory Medicine is aimed at introducing the student to the logic and tools underlying the execution of the diagnostic tests of the Clinical Biochemistry, Clinical Pathology, Clinical Microbiology, Clinical Parasitology and Rheumatology. At the end of the integrated teaching, the student will be able to apply diagnostic tests in the clinical practice, and to interpret and evaluate their results.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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VET/06
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Contact Hours
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10
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Type of Activity
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Core compulsory activities
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Teacher
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Di Cave David
(syllabus)
Metazoan parasites: Flatworms, Flukes and Roundworms (Cestodes, Trematodes and Nematodes) Laboratory diagnosis of parasitic diseases
(reference books)
• “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446 • Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor • Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke Second edition • Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition • Harrison’s Rheumatology, latest edition • Harrison’s Principle of Internal Medicine, latest edition • Oxford Handbook of Rheumatology, latest edition
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Oral exam
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Module: Rheumatology
(objectives)
The integrated teaching of Laboratory Medicine is aimed at introducing the student to the logic and tools underlying the execution of the diagnostic tests of the Clinical Biochemistry, Clinical Pathology, Clinical Microbiology, Clinical Parasitology and Rheumatology. At the end of the integrated teaching, the student will be able to apply diagnostic tests in the clinical practice, and to interpret and evaluate their results.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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MED/16
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Contact Hours
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10
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Type of Activity
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Core compulsory activities
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Teacher
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Priori Roberta
(syllabus)
Rheumatology Classification of rheumatic diseases. Autoimmune and inflammatory disorders of rheuatologic interest: pathogenesis, clinical presentation, epidemiology, course, basic management and prognosis. The role of laboratory investigations for the diagnosis of rheumatic diseases. Sjogren’s syndrome. Systemic Lupus Erythematosus. Systemic sclerosis. Mixed connective tissue disease. Undifferentiated connective tissue disease. Antiphospholipid antibodies syndrome. Idiopatic Inflammatory myopathies. Systemic Vasculitis. Autoinflammatory diseases. Introduction to rheumatoid arthritis.
(reference books)
• “Tietz fundamentals of Clinical Chemistry and molecular diagnostics”. 8th ed. N. Rifai, A.R. Horvath, C.T. Wittwer, Elsevier 2019. ISBN-13: 978-0323530446 • Michael Laposata. “Laboratory Medicine: the diagnosis of disease in the clinical laboratory” (3rd edition). LANGE editor • Oxford handbook - “Infectious diseases and microbiology” – E Torok, E. Moran, F Cooke Second edition • Wolters Kluwer – “Color atlas and textbook of Diagnostic Microbiology” – GW Procop, DL Church, GS Hall, WM Janda, EW Konemar, PC Schreckenberger, GL Wood – Seventh Edition • Harrison’s Rheumatology, latest edition • Harrison’s Principle of Internal Medicine, latest edition • Oxford Handbook of Rheumatology, latest edition
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
|
Evaluation methods
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Oral exam
|
|
|
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