Medical oncology and blood diseases
(objectives)
Students will need to know the predisposing conditions and the clinical characteristics of the various neoplastic diseases, prognostic and predictive factors related both to the neoplasm and to the patient, hematopoietic and lymphoid system and its physiopathological disorders. Moreover, students are asked to know the main laboratory analysis systems, the cellular isolation methods, standard molecular biology techniques commonly used in the oncohematological, how to store hematological samples, how to apply diagnostic technologies required for diagnostic and prognostic assessment of hematological patients. Students will have to possess the notions and principles relating to Diagnostic Imaging (including interventional radiology) to integrate the knowledge of the professional profile with those relating to diagnostic imaging technologies.These objectives will be achieved through lectures aimed at improving students’ learning capabilities in order to achieve useful skills for collaboration with multidisciplinary teams. These objectives will be verified through in itinere and final tests.
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Code
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90287 |
Language
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ENG |
Type of certificate
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Profit certificate
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Module: Medical oncology
(objectives)
Students will need to know the predisposing conditions and the clinical characteristics of the various neoplastic diseases, tumor markers and molecules that might help to define diagnostic procedures. The knowledge of prognostic and predictive factors linked to the characteristics related to the neoplasm and to the patient, will help to understand the strategy for the management of different tumors, taking into account the therapeutic options available in the various phases of the disease and their side effects in a risk/benefit assessment perspective in order to achieve useful skills for collaboration with multidisciplinary teams. These objectives will be achieved through lectures aimed at improving the ability to address and resolve the main issues of Oncology.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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5
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Scientific Disciplinary Sector Code
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MED/06
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Contact Hours
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50
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Type of Activity
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Core compulsory activities
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Teacher
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Riondino Silvia
(syllabus)
◦ Epidemiology of cancer and prevention ◦ Prognostic and predictive risk factors ◦ Carcinogenesis, cancer growth and proliferation, cancer immune tolerance ◦ Assessment and investigations of patients with cancer, including history, physical examination, laboratory and imaging techniques. Performance Status Evaluation (Karnofsky and ECOG scores) ◦ Tumour staging ◦ Response Evaluation Criteria In Solid Tumours (RECIST) ◦ Principles of therapy of oncological diseases and clinical effects of therapeutic approaches used: Surgery, radiotherapy, cytotoxic approach (neoajuvant, adjuvant, metastatic and palliatives approaches), target therapy and immune anti-cancer agents. Drug resistance ◦ Management of medical emergencies and complications resulting from cancer or its treatment ◦ Clinical Trials in oncology ◦ Tumor markers
(reference books)
◦ Chmielowski B., Territo M.C. Manual of Clinical Oncology. Ed: Lippincott Williams and Wilkins. ISBN 9781496349576Appointments will be set according to students’ requests.
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
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Module: Blood diseased, oncohematology
(objectives)
The main objectives of the course are the understanding of: • hematopoietic and lymphoid system and its physiopathological disorders; • the main laboratory analysis systems; • cellular isolation methods; • standard molecular biology techniques commonly used in the oncohematological field; • correct and efficient storage of hematological samples; • how to apply diagnostic technologies needed to help the assessment of the diagnosis and prognosis of hematological patients These objectives will be achieved through test in itinere and lectures.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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5
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Scientific Disciplinary Sector Code
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MED/15
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Contact Hours
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50
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Type of Activity
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Core compulsory activities
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Teacher
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Fabiani Emiliano
(syllabus)
• Bone marrow nice • Haematopoietic stem cell • Haematopoiesis • Anemia • Clonal haematopoiesis • Myelodysplastic syndrome • Acute myeloid leukaemia • Acute lymphoblastic leukaemia • Myeloproliferative disorders • Chronic myeloid leukaemia • Lymphoma • Peripheral blood sampling and bone marrow aspirate • Haematological cell culture technics • Peripheral blood and bone marrow smear • Isolation of mono and polymorphonuclear cells • Stem cell isolation: culture, amplification and cryopreservation • Cytofluorimetry • Karyotype aberrations: conventional and molecular cytogenetics (FISH) • Diagnostic and prognostic role of molecular biology in oncohaematology • Extraction and storage of nucleic acids (DNA and RNA) for haematological tests • Basic techniques in molecular biology: nucleic acids amplification • Qualitative analysis (PCR and RT-PCR), diagnostic approach • Minimal residual disease • Qualitative analysis (PCR and RT-PCR), prognostic approach • Gene mutations • Sanger sequencing • New generation sequencing and personalized medicine: applications, progress, costs and benefits
(reference books)
• Hematology: pathophysiology, diagnosis and treatment. Sante Tura, Michele Cavo e Pier Luigi Zinzani. Casa editrice Esculapio. • The slides shown during the course will be made available to the student and will constitute the reading material for the haematological diagnostic techniques.
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Module: Diagnostic imaging
(objectives)
Students will have to possess the notions and principles relating to Diagnostic Imaging (including interventional radiology) to integrate the knowledge of the professional profile with those relating to diagnostic imaging technologies. These objectives will be achieved through lectures aimed at improving students’ learning capabilities and will be verified through in itinere and final tests.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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MED/36
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Contact Hours
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10
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Type of Activity
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Core compulsory activities
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Teacher
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Bassetti Erica
(syllabus)
• General principles of ionizing and non-ionizing radiation • Diagnostic imaging equipment • Conventional radiology equipment overview of the equipment and their use • Computed Tomography equipment overview of the equipment and their use • Radiology equipment for panoramic interventional radiology applications of equipment and their use • Radiology equipment for panoramic radiotherapy applications of equipment and their use • Evaluations on the dose to be administered to the patient • Targeted choice of the exam to be carried out based on the clinical problem • Dose / benefit ratio • Elements of multidisciplinary radiological anatomy
(reference books)
Compendio di Radiologia R. Passariello, G. Simonetti • The slides and the articles shown during the course will be made available to the student and will constitute the reading material for the course of Diagnostic Imaging
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
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