pathological anatomy 2
(objectives)
The Anatomic pathology II course aims to provide the main notions of Cytopathology, Histopathology, Autopsy Technique, Autopsy And Clinical Diagnosis, Digital Pathology and Molecular Pathology Techniques, as well as the basis of laboratory techniques, research and diagnostics in Anatomic Pathology. Mandatory objectives are the knowledge of the basic principles, organization, methodologies and technical laboratory and cognitive-diagnostic activities carried out in the clinical service of Anatomic Pathology. The student must learn the basic principles of Cytopathology, Histopathology, Autopsy Technique, Autopsy and Clinical Diagnosis, Digital Pathology and Molecular Pathology Techniques. They must also acquire knowledge and skills in the main technologies (immunohistochemistry, molecular biology, digitization of histological and cytological preparations) to carry out research and diagnostic activities in Anatomic Pathology. These objectives will be achieved through lectures designed to facilitate learning and improve the ability to solve the main questions of Cytopathology, Histopathology, Autopsy Technique, Autopsy and Clinical Diagnosis, Digital Pathology and Molecular Pathology Techniques and laboratory protocols used in research and in the diagnostic.
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Code
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90163 |
Language
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ENG |
Type of certificate
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Profit certificate
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Module: elements of autopsy, cytopathological, histological diagnostics, autopsy techniques
(objectives)
The student will be able (i) to know the basic macroscopic and optical microscopic anatomical lesions of the main pathologies of the various apparatus and (ii) to understand the role of histological, immunohistochemical and molecular biology investigations in the anatomopathological diagnostic process both in the care diagnostic workflow and in the realization and drafting of basic and applied research projects. Essential objectives • the acquisition of basic knowledge of the histopathological characteristics of the main pathologies of the various apparatuses (hemolympopoietic, lungs, breast, thyroid, oesophagus, stomach, intestine, liver, kidneys, bladder, prostate, testicles, cervix, uterus and ovary). • the acquisition of basic knowledge for performing immunohistochemical reactions • the acquisition of basic notions for the use of the main antibodies for immunohistochemical reactions • the acquisition of basic notions for the use of the main detection systems and chromogens in immunohistochemistry • the acquisition of basic knowledge about the use of the main antibodies used in the pathological diagnostics
o to evaluate the correct preparation of a cytological samples; o the criteria used in analyzing cytological samples under the microscope; o the morphological characteristics of normal, reactive, atypical, dysplastic and neoplastic cells; o to recognize under the microscope normal and pathological human cells, both in diagnostic and care processes and in the execution and drafting of basic and applied research projects.
These objectives will be achieved through lectures, exercises and interactive teaching activities.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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2
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Scientific Disciplinary Sector Code
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MED/08
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Contact Hours
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20
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Personal Study Hours
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-
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Type of Activity
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Core compulsory activities
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Credits
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2
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Scientific Disciplinary Sector Code
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MED/08
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Contact Hours
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20
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Personal Study Hours
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-
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Type of Activity
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Core compulsory activities
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Teacher
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Bonanno Elena
(syllabus)
Purpose of cytological examination Indications, advantages and limitations of cytological examination Types of cytological examination: exfoliative and needle aspiration cytology Preparation of cytological samples: smear, thin layer, cell-block, cytocentrifugation Fixation and histochemical staining of cytological samples. Application of special techniques in cytological diagnostics as immunocytochemistry, cytofluorimetry and FISH Evaluation of cytological samples: criteria of adequacy of sampling and preparation Evaluation of morphological characteristics of cells: normal, hyperplastic, atypical, neoplastic cells. Criteria of malignancy. Bethesda system and other main classifications Quality control. Artifacts; false negatives; false positives Diagnostic cytopathology of the female genital apparatus: PAP test and breast cytology. Diagnostic thyroid cytopathology Diagnostic lung cytopathology Diagnostic of urinary tract cytopathology Diagnostic cytopathology of effusions
(reference books)
Recommended textbooks: Subject: FUNDAMENTALS OF CYTOPATHOLOGY • Comprehensive Cytopathology 7th Edition, Marluce Bibbo, David C. Wilbur, 2015, Elsevier
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Oral exam
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Teacher
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Fattore Santeusanio Giuseppe
(syllabus)
AUTOPSY AND CLINICAL DIAGNOSIS Definition of autopsy History and purpose of the autopsy Autopsy as an instrument for clinical control Autopsy as a risk management tool Autopsy as a tool for improving the quality of clinical-assistance pathways The autopsy rooms Safety Measures to be taken during autopsy procedures General standards of biosafety in the autopsy room The autopsy report as data storage and research support Post-mortem phenomena ELEMENTS OF DIGITAL PATHOLOGY Digital slides Technologies for digitalization of histological slides Virtual Microscopy Role of Digital Pathology in clinical-diagnostic, training and research activities Digital Pathology in Consultancy and Second Opinion (Telepathology) Digital technology and machine learning systems in Anatomic Pathology Privacy and data management
(reference books)
Recommended textbooks: Subject : AUTOPSY AND CLINICAL DIAGNOSIS – ELEMENTS OF DIGITAL PATHOLOGY • AUTOPSY IN THE 21ST CENTURY: BEST PRACTICES AND FUTURE DIRECTIONS Jody E. Hooper and Alex K. Williamson Editors, 2019, Springer Nature Switzerland • DIGITAL PATHOLOGY Yves Sucaet, Wim Waelput, 2014, Springer Briefs in Computer Science
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Oral exam
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Teacher
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Anemona Lucia
(syllabus)
FUNDAMENTALS OF HISTOPATHOLOGY Histopathological neoplasms classification Immunohistochemical techniques. Application of immunohistochemical techniques in histopathological diagnostics as an indispensable tool for the typing of neoplasms, the study of prognostic and predictive biomarkers. Basic histopathological aspects of the pathology of the hemolymphoproietic apparatus. Basic histopathological aspects of lung pathology. Basic histopathological aspects of breast pathology. Basic histopathological aspects of thyroid pathology. Basic histopathological aspects of gastrointestinal pathology (esophagus, stomach, intestine, liver). Basic histopathological aspects of urinary tract pathology (kidney, bladder). Basic histopathological aspects of male genital pathology (prostate, testicles) Basic histopathological aspects of the pathology of the female genital apparatus (cervix, uterus and ovary).
(reference books)
Recommended textbooks: Subject : FUNDAMENTALS OF HISTOPATHOLOGY • Robbins & Cotran Pathologic: Basis of Disease Vinay Kumar, Abul K. Abbas, Jon C. Aster, 10th Ed (2020), Elsevier • Rubin's Pathology: Clinicopathologic Foundations of Medicine 7th Ed., Editor David S. Strayer and Emanuel Rubin, 2015 Wolters Kluwer Health
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Oral exam
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Teacher
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Mauriello Alessandro
(syllabus)
External examination of the corpse Main docimasic tests Autopsy technique for the opening of the chest cavity and the evisceration of the heart and lungs. Autopsy technique for the opening of the abdominal cavity and the evisceration of the liver, stomach, large and small intestine and spleen. Autopsy technique for the evisceration of extra-peritoneal organs: aorta, kidneys, bladder, prostate, uterus and ovary. Autopsy technique for the opening of the cranial box and the evisceration of the encephalon. Basic knowledge about macroscopic alterations of some autoptic organs , in particular of the heart, lung, liver, spleen, kidney, bladder, uterus, ovary and brain.
(reference books)
Recommended textbooks: PRINCIPLES OF AUTOPSY TECHNIQUE • AUTOPSY IN THE 21ST CENTURY: BEST PRACTICES AND FUTURE DIRECTIONS Jody E. Hooper and Alex K. Williamson Editors, 2019, Springer Nature Switzerland • THE HOSPITAL AUTOPSY: A MANUAL OF FUNDAMENTAL AUTOPSY PRACTICE Third Edition, Julian L. Burton and Sheffield Guy Rutty, 2010 Hodder Arnold
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Oral exam
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Module: molecular pathology techniques
(objectives)
The essential objectives of the course are: the acquisition of basic knowledge about the main techniques used in the molecular pathology laboratory for the extraction of nucleic acids such as PCR and F.I.S.H. These objectives will be achieved through lectures and interactive teaching activities, designed to facilitate learning and improve the ability to solve problems related to the execution of molecular pathology techniques.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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MED/46
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Contact Hours
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10
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Type of Activity
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Core compulsory activities
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Teacher
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D'Angelo Martina
(syllabus)
Main methods of nucleic acid extraction: from the pre-analytical phase to the evaluation Techniques and Applications of PCR in Molecular Pathology Techniques and Applications of F.I.S.H. in Molecular Pathology
(reference books)
Teaching materials such as handouts, presentations and scientific articles will be provided to the students
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Oral exam
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