Biology, applied physics, biochemistry
(objectives)
Aim of the teaching is to provide students with knowledge on the fundamentals of applied physics, biochemistry, medical genetics and biology necessary to the performance of their future activity. At the end of the course, the students will know the fundamental concepts of application of the Scientific Method to the study of biomedical phenomena (choice and measure of parameters, evaluation of errors), they will be able to describe physical phenomena of complex systems using suitable mathematical tools, they will know the scientific basis of medical procedures and principles of functioning of the equipment commonly used for diagnostics and therapeutics. Students will learn knowledge on the structure, function, and regulation of biological macromolecules (carbohydrates, lipids, amino acids and proteins). To acquire basic knowledge on the main metabolic pathways and cycles with particular regard to carbohydrate, lipid and amino acid metabolism. Students will learn with knowledge on the main notions on inheritance of monogenic, chromosomal and multifactorial diseases. At the end of the course the student will be able to distinguish the main classes of genetic diseases and to recognize the modes of transmission of hereditary diseases. Students will learn knowledge related to the physiological and morphological characteristics of cells, as functional units of living organisms. Another important goal is to utilize the experimental method to understand the biological mechanisms that regulate life and as a tool for the study of pathological processes.
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Code
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90348 |
Language
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ITA |
Type of certificate
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Profit certificate
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Module: Biochemistry
(objectives)
The Biochemistry course aims to provide students with the biochemical basis necessary for understanding the relationship between structure and function of the main classes of biomolecules. The main objectives of the course are: to know and integrate the metabolism of carbohydrates, lipids and proteins; to know the mechanism of action of hormones and the modalities of regulation of some of them on the main metabolic pathways.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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BIO/10
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Contact Hours
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14
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Type of Activity
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Basic compulsory activities
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Teacher
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Naviglio Silvio
(syllabus)
Amino acids. Protein. Generalities and functions. The peptide bond and the primary sequence, secondary, tertiary and quaternary structure. Myoglobin, hemoglobin. Notes on Collagen. Enzymes. Role and mechanism of action of enzymes. Enzymatic regulation. Covalent regulation and allosteric regulation. Isoenzymes (LDH, CPK). Vitamins. Classification of structure and functions, water-soluble vitamins and fat-soluble vitamins, Vitamin D and calcium and phosphorous metabolism. Metabolism General concepts. Catabolic and anabolic pathways. Bioenergetics principles. ATP: biological structure and role. Structure and metabolism of carbohydrates. Monosaccharides, disaccharides. Reserve polysaccharides. Digestion and absorption of carbohydrates in the diet. Glycolysis: stages and regulation. Krebs cycle: general concepts, regulation. Oxidative phosphorylation and electron transport chain, outline. Energy balance of carbohydrate catabolism. Outlines on the pentose cycle and on gluconeogenesis. Glycogen metabolism. Metabolism of amino acids. Catabolism of diet proteins and digestive enzymes. Essential and non- essential amino acids. Amino acids as precursors of nitrogen compounds. Aminoacid catabolism: transamination and deamination, destiny of the carbon skeleton. Biosynthesis of urea. Structure and metabolism of lipids. Classification of lipids (cell lipids and reserve lipids, simple and complex lipids). Fatty acids: general structure and main fatty acids. Structure and function of triglycerides and phospholipids. Cholesterol. Digestion and absorption of lipids; plasma lipoproteins:
(reference books)
David L Nelson Michael M Cox. "Introduzione alla biochimica di Lehninger". David L Nelson Michael M Cox "Lehninger Principles of Biochemistry".
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Oral exam
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Module: Medical genetics
(objectives)
The aim of the course of Medical Genetics is to provide to students the knowledge on the main notions on inheritance of monogenic, chromosomal and multifactorial diseases. At the end of the course the student will be able to distinguish the main classes of genetic diseases and to recognize the modes of transmission of hereditary diseases.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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MED/03
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Contact Hours
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14
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Type of Activity
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Basic compulsory activities
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Teacher
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Ciccacci Cinzia
(syllabus)
Basic Genetics: Definitions of Key Terms: gene, locus, allele, genotype, phenotype, haplotype, homozygous, heterozygous, haploid, diploid, dominance, recessivity, codominance, mutation, polymorphism. Principles of Genetic Transmission: Mendel's Genetic Hypothesis, The Monohybrid and dihybrid Crosses, Segregation in Human Pedigrees, Blood groups Genetics Monogenic Inheritance Models: Autosomal inheritance,Autosomal recessive inheritance, X-linked inheritance Genetic Risk calculation and pedigrees Chromosomes: Structure and Analysis, Chromosomes Pathologies Genomic Imprinting X-chromosome inactivation Mitochondrial inheritance: mitochondrial DNA, pattern of inheritance Multifactorial inheritance: polimorphisms, susceptibility genes, gene-environment interaction, association studies Pharmacogenomics and Personalised Medicine Genetic tests and Counselling. Outlines
(reference books)
Lectures in pdf format will be provided to students. Recommended books: “Genetica in Medicina”, by Nussbaum, McInnes, Willard. Edises “Genetica Medica Essenziale” by Dallapiccola, Novelli. Ciceditore
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Module: Applied physics
(objectives)
Aim of the course of AppliedPhysicswithin the integrated course of Biology, AppliedPhysics andBiochemistryis to providestudentswithknowledge on the fundamentals of appliedphysicsnecessary to the performance of their future activity. In particular, the comprehension of physicalprinciples at the base of medicalphysics and of functioning of medical instrumentation willbeaddressed. At the end of the course, the studentswill know the fundamental concepts of application of the Scientific Method to the study of biomedicalphenomena (choice and measure of parameters, evaluation of errors), theywillbe able to describephysicalphenomena of complexsystemsusingsuitablemathematicaltools, theywill know the scientific basis of medicalprocedures and principles of functioning of the equipmentcommonlyused for diagnostics and therapeutics.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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FIS/07
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Contact Hours
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14
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Type of Activity
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Basic compulsory activities
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Teacher
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Indovina Iole
(syllabus)
Chapter1: Introduction, Measurement, Estimating
1.4: Measurement and Uncertainty; Significant Figures 1.5: Units, Standards, and SI Units 1.6: ConvertingUnits 1.8: Dimensions and DimensionalAnalysis
Chapter14:Heat
14.1 Heat as Energy Transfer 14.2 InternalEnergy 14.3: SpecificHeat 14.4: Calorimetry 14.5: Latent Heat 14.6: Heat Transfer: Conduction 14.7: Heat Transfer: Convection 14.8: Heat Transfer: Radiation
Chapter15: The Laws of Thermodynamics
15.1: The First Law of Thermodynamics 15.2: ThermodynamicProcesses and the First Law
Fluids
Chapter10:Fluids
10.1: Phases of Matter 10.2: Density and SpecificGravity 10.3: Pressure in Fluids 10.4: Atmospheric Pressure Gauge Pressure 10.5: Pascal'sPrinciple 10.6: Measurement of Pressure; Gauges and the Barometer 10.7: Buoyancy and Archimedes' Principle
Vibrations and Waves
Chapter11: Vibrations and Waves
11.7: Wave Motion 11.8: Types of Waves: Transverse and Longitudinal 11.9: EnergyTransported by Waves 11.10: IntensityRelated to Amplitude and Frequency
Chapter12: Sound
12-1 Characteristics of Sound 12-2 Intensity of Sound: Decibels 12-7 Doppler Effect
Electricity and Magnetism
Chapter16: Electric Charge and Electric Field
16.1: StaticElectricity; Electric Charge and its Conservation 16.2: Electric Charge in the Atom 16.3: Insulators and Conductors 16.4: Induced Charge; the Electroscope 16.5: Coulomb's Law 16.6: SolvingProblemsInvolvingCoulomb's Law and Vectors 16.7: The Electric Field 16.8: Field Lines 16.9: Electric Fields and Conductors
Chapter17: Electric Potential
17.1: Electric PotentialEnergy and PotentialDifferences 17.2: Relation Between Electric Potential and Electric Field 17.3: Equipotential Lines 17.4: The Electron Volt, a Unit of Energy 17.5: Electric Potential Due to Point Charges 17.7: Capacitance 17.8: Dielectrics 17.9: Storage of Electric Energy
Chapter18: Electric Currents
18.1: The Electric Battery 18.2: The Electric Current 18.3: Ohm's Law: Resistance and Resistors 18.4: Resistivity 18.5: Electric Power
Chapter19: DC Circuits
19.1: EMF and Terminal Voltage 19.2: Resistors in Series and in Parallel 19.3: Kirchhoff'sRules 19.4: EMFs in Series and in Parallel; ChargingaBattery 19.5: Circuits ContainingCapacitors in Series and in Parallel 19.6: RC Circuits-Resistor and Capacitor in Series
(reference books)
Douglas C. Giancoli“PHYSICS: Principleswith Applications” Seventhedition or subsequent, Pearson Education. Inc
The indicated textbook is just a reference. Students are allowed to adopt the book/books of their choice. Additional material will be provided by the instructor.
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Module: Applied biology
(objectives)
The Biology module aims at providing the students with the morphological and functional organization of prokaryotic and eukaryotic cells, focusing on both the descriptive aspects and the basic notions of biochemistry and cellular physiology required to understand the functions of the cell as a basic unit of living organisms. The objective of the course is the learning of the constructive logic of the biological structures at the different levels of organization of living matter, the principles that govern the functioning of the different biological systems, the learning of the experimental method and its applications to the study of biological phenomena. Students will learn the unitary mechanisms that regulate cellular activities, gene expression and genetic material transmission.
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Language
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ITA |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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BIO/13
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Contact Hours
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14
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Type of Activity
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Basic compulsory activities
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Teacher
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Carotenuto Felicia
(syllabus)
Characteristic of living cells: Cellular theory. Classification principles of living organisms. Prokaryotic and eukaryotic cell models: classification and major structural differences. Cell Chemistry: Macromolecules: structure, shape and function Plasma membrane: properties and functions. Internal organization of the cell: Cellular compartments. Cytoplasm and cytoplasmic organelles, ribosomes, smooth and rought endoplasmic reticulum, Golgi apparatus, lysosomes, peroxisomes. The cytoskeleton. Microtubules, intermediate filaments and microfilaments. Cilia and flagella. Centrioles and centrosomes. Energy conversion: Glycolysis, fermentation, cellular respiration, photosynthesis. (outline). Mitochondria and Chloroplasts, structure and function. Molecular basis of hereditary information: DNA replication. DNA repair and its correlation with human diseases. RNA, structure and function: Main types of cellular RNAs and differences with respect to DNA in terms of molecular size, stability and biological functions. Transcription and RNA maturation. Genetic Code and its properties. Protein synthesis: How cells read the genome Cellular Reproduction, Mitosis and Meiosis.
(reference books)
Sadava, Hillis, Heller, Hacker. Elementi di Biologia e Genetica Zanichelli editore, V ed. • Raven,Johnson, Mason, Losos, Singer. Elementi di Biologia e Genetica Piccin editore II ed.
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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