The student must learn the general characteristics of antigens, antibodies, cytokines; cells, tissues and organs of the immune system; the mechanisms of regulation of central and peripheral tolerance; the components and molecular mechanisms of innate and adaptive immune responses. Furthermore, the student must learn the main immune mechanisms of pathogenetic relevance, in particular: the hypersensitivity reactions, the immunodeficiencies, the autoimmune disorders, transplantation and tumor immunology. These objectives will be achieved through lectures designed to facilitate learning and improve the ability to address and resolve the main questions of immunology and immunopathology.
General characteristics of the immune response. Innate immunity. Cells and tissues of the immune system. Leukocyte migration. Antibodies and repertoire diversity. Monoclonal antibodies. B lymphocyte development and humoral immunity. Complement. Major Histocompatibility Complex and Antigen presentation to T lymphocytes. T lymphocyte cell-mediated immunity.