biochemistry, physiology and microbiology
(objectives)
at the end of the course on Biochemistry, physiology and general microbiology, the student would have understood the importance of main mechanisms that govern homeostatic processes, metabolic pathways and their regulation through metabolic and hormonal control. With the aid of molecular biology a modern practice with aim to improve understanding of biological phenomenoms and their complexity and allows a igh level laboratory diagnosis like in the field of biochemistry. Acquire the basic concepts of special bacteriology and mycology.
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Code
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90150 |
Language
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ENG |
Type of certificate
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Profit certificate
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Module: physiology
(objectives)
The aim of the teaching is, starting from the knowledge of the basic concepts and the normal quantitative parameters of the bodily functions and their variations in the different conditions of dynamic engagement, to develop in the student the ability to understand the principles of the functioning of the human body. The cellular mechanisms and the integrated functions of the main organs and apparatuses aimed at the maintenance of body homeostasis will also be analyzed in the context of environmental modifications
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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2
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Scientific Disciplinary Sector Code
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BIO/09
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Contact Hours
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20
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Type of Activity
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Basic compulsory activities
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Teacher
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Pallone Gabriele
(syllabus)
Physiology of the cell membrane: 2 hours
Membrane transport of ions and molecules Membrane potential and Action Potential
Muscle Physiology: 4 hours
Excitation and contraction of skeletal muscle tissue. Neuromuscular transmission and excitation-contraction coupling. Motor unit
Physiology of the Nervous System: 4 hours
The Afferent Division: decoding and processing of sensory information. The Efferent Division: general characteristics of the motor system: involuntary, voluntary and automatic movements; spinal reflexes; the brain-encephalic control of the movement: posture and balance. Cortical control of voluntary movements. The cerebellum: general features, functions of the cerebellum. The basal ganglia: functional role. The Autonomic Nervous System. Supplementary functions of the nervous system.
Cardiovascular physiology: 4 hours
Myocardial physiology: functional myocardial anatomy, myocardial action potentials, contraction of the heart muscle. Cardiac cycle Nervous control of cardiac activity. General principles of hemodynamics. Adjustment of circulation, blood pressure and blood flow. Cardiac output: principles of regulation of cardiac output. Cardiac tones. The Respiratory System: 2 hours
Pulmonary ventilation: respiratory mechanics, volumes and lung capacity. Respiratory tract Gaseous exchanges: diffusion of oxygen and carbon dioxide through the respiratory membrane. Transportation of oxygen and carbon dioxide in blood and body fluids .. Regulation of breathing: general principles. Regulation of acid-base balance: general principles.
Body fluids and renal function: 2 hours
Functional anatomy of the kidney, function of the nephron. Glomerular filtration: general principles. Elaboration of glomerular filtrate: resorption and tubular secretion, Control of osmolarity and sodium concentration of extracellular fluid: general principles.
Renal regulation of blood volume: general principles The endocrine system: 2 hours
General principles of endocrinology: nature of a hormone; general picture of the endocrine glands and their hormones. Principles of general functioning of hormones.
(reference books)
-“Berne & Levy Physiology”, Sixth Updated Edition -“Sherwood” ninth edition -“Guyton-Hall
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Module: biochemistry
(objectives)
The course aims to help study the knowledge of biochemistry with particular reference to the structure of macromolecules and their metabolism
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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4
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Scientific Disciplinary Sector Code
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BIO/10
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Contact Hours
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40
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Type of Activity
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Basic compulsory activities
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Teacher
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Di Venere Almerinda
(syllabus)
ELEMENTS OF CHEMISTRY: Atomic structure. Electronic orbitals. The periodic table. The chemical bond. Molecular structure. Brute formula and structure formula. Valence (in particular H, alkali metals, halogens, C, N, O). Covalent bond and hydrogen. Definitions and examples of hydrides, oxides, acids, bases and salts. Nomenclature. Notes on oxide-reduction. The ionic product of water and pH. Strong acids and bases. Weak acids and bases. Buffers. The size and the molar concentration. Basic groups of organic chemistry (hydroxyl, ketonic, aldehyde, aminic, carboxylic, thiolic).
- ELEMENTS OF STRUCTURAL BIOCHEMISTRY: Protein structure: generic formula of an amino acid and peptide bond. Essential and non-essential amino acids. Secondary, tertiary and quaternary structures of proteins. Fibrous and globular proteins. Hemoglobin and myoglobin. Functions of proteins. Enzyme concept (active site, substrate bonding). Enzymatic kinetics. Structure of sugars: monosaccharides (glyceraldehyde, glucose, fructose, ribose, deoxyribose); disaccharides (sucrose, maltose); reserve polysaccharides (glycogen, starch); structure polysaccharides (cellulose). Structure of fatty acids: saturated and unsaturated fatty acids. Stearic, oleic, palmitic, linoleic acid. Triacylglycerols and their properties.Lipid membranes and cholesterol (outline). Hormones: 4. General properties of hormones. The hormonal "cascade" (from the hypothalamus to the pituitary gland and from these to the main glands). Mechanisms of action of peptide and steroid hormones. Vitamins: Characteristics of the main water-soluble vitamins and of the four fat-soluble vitamins. -METABOLISM AND ENERGY: Transformation of energy into living things. C. cycle Anabolism (overview of chlorophyll photosynthesis) and glucose catabolism. Structure of ATP and NADH. Glycolysis, fermentation and cellular respiration. Metabolism evolution Fat catabolism: β-oxidation. Summary scheme of the catabolism of amino acids, sugars and lipids.
(reference books)
Biochemistry Denise Ferrier Lippincott Williams & Wilkins • ISBN-10: 149636354X • ISBN-13: 978-1496363541
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Teacher
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Nicolai Eleonora
(syllabus)
ELEMENTS OF CHEMISTRY: Atomic structure. Electronic orbitals. The periodic table. The chemical bond. Molecular structure. Brute formula and structure formula. Valence (in particular H, alkali metals, halogens, C, N, O). Covalent bond and hydrogen. Definitions and examples of hydrides, oxides, acids, bases and salts. Nomenclature. Notes on oxide-reduction. The ionic product of water and pH. Strong acids and bases. Weak acids and bases. Buffers. The size and the molar concentration. Basic groups of organic chemistry (hydroxyl, ketonic, aldehyde, aminic, carboxylic, thiolic).
- ELEMENTS OF STRUCTURAL BIOCHEMISTRY: Protein structure: generic formula of an amino acid and peptide bond. Essential and non-essential amino acids. Secondary, tertiary and quaternary structures of proteins. Fibrous and globular proteins. Hemoglobin and myoglobin. Functions of proteins. Enzyme concept (active site, substrate bonding). Enzymatic kinetics. Structure of sugars: monosaccharides (glyceraldehyde, glucose, fructose, ribose, deoxyribose); disaccharides (sucrose, maltose); reserve polysaccharides (glycogen, starch); structure polysaccharides (cellulose). Structure of fatty acids: saturated and unsaturated fatty acids. Stearic, oleic, palmitic, linoleic acid. Triacylglycerols and their properties.Lipid membranes and cholesterol (outline). Hormones: 4. General properties of hormones. The hormonal "cascade" (from the hypothalamus to the pituitary gland and from these to the main glands). Mechanisms of action of peptide and steroid hormones. Vitamins: Characteristics of the main water-soluble vitamins and of the four fat-soluble vitamins. -METABOLISM AND ENERGY: Transformation of energy into living things. C. cycle Anabolism (overview of chlorophyll photosynthesis) and glucose catabolism. Structure of ATP and NADH. Glycolysis, fermentation and cellular respiration. Metabolism evolution Fat catabolism: β-oxidation. Summary scheme of the catabolism of amino acids, sugars and lipids.
(reference books)
Biochemistry Denise Ferrier Lippincott Williams & Wilkins • ISBN-10: 149636354X • ISBN-13: 978-1496363541
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Module: applied biochemistry
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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BIO/12
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Contact Hours
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10
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Type of Activity
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Basic compulsory activities
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Teacher
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Montagna Costanza
(syllabus)
Solutions Concentration, molarity, molality, molar ratio, dilution, stoichiometry.
Immunochemistry General aspects of the immune system, production of antibodies, enzyme immunoassay, radioimmunoassay, immunoprecipitation.
Purification of proteins Tissues homogenization, fractional precipitation.
Centrifugation Principles of centrifugation, preparative centrifugation, centrifuges and rotors.
Electrophoretic techniques General principles, supports used in electrophoresis, polyacrylamide gel electrophoresis (PAGE), SDS-PAGE, isoeletrofocusing, two-dimensional electrophoresis, Western blotting, capillary electrophoresis.
(reference books)
(Biochemistry, Denise Ferrier, Lippincott Williams & Wilkins).
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Module: microbiology
(objectives)
The course aims to provide an in-depth knowledge of the infections by viruses, bacteria and fungi, with particular attention to the different classes and microbial families.
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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2
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Scientific Disciplinary Sector Code
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MED/07
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Contact Hours
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20
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Type of Activity
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Core compulsory activities
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Teacher
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Armenia Daniele
(syllabus)
Overview viral families Paramyxovirus Orthomixovirus picornavirus Retrovirus Togavirus Hepatitic viruses Herpes virus papovavirus Adenovirus, Parvovirus, Poxvirus Ebola and other viruses, Prioni Overview of bacterial families Bordetella Chlamydia Haemophilus Enterobacteriaceae Mycoplasmas and Ureoplasms Spirochetes Overview of the mycetes
(reference books)
Title: The basics of Microbiology Authors: Richard A. Harvey, Pamela C. Champe Bruce D. Fisher
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
Oral exam
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Module: technical sciences of laboratory medicine
(objectives)
At the end of the course, the student will have acquired knowledge on the main analytical investigations in a clinical biochemical laboratory
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Language
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ENG |
Type of certificate
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Profit certificate
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Credits
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1
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Scientific Disciplinary Sector Code
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MED/46
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Contact Hours
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10
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Type of Activity
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Core compulsory activities
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Teacher
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Casalino Paolo
(syllabus)
Contents
Organization of a laboratory
Knowledge of the main laboratory instruments
Types of tubes (with and without anticoagulants) used in analytical investigations
Blood count and basic concepts on blood tests
The various stages of an analytic process
(reference books)
Slides and materials provided by course professor
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Dates of beginning and end of teaching activities
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From to |
Delivery mode
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Traditional
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Attendance
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Mandatory
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Evaluation methods
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Written test
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