Lacconi Valentina
Docente a contratto esterno-Art.23 Legge 240/10
Scientific Disciplinary Sector Code
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ISTOLOGIA (BIO/17)
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University
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Saint Camillus International University of Health Sciences
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College/Department
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Department
Facoltà dipartimentale di Medicina
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Reception times
WORK EXPERIENCE
April 2023 Teaching Fellow in Histology at University of Tirana, Nostra Signora del Buon Consiglio (Degree in Medicine and Surgery)
October 2021-Now Research Fellow, Post-doctoral at University of Rome Tor Vergata, Department of Biomedicine and
Prevention, Histology section.
March 2021-Now Teaching Fellow in Cytology and Histology at UniCamillus – Saint Camillus International University
of Health and Medical Sciences (Degree in Medicine and Surgery; Degree in Dentistry
and Dental Prosthetics).
2020-2022 Tutoring activity in Citology and Histology teaching at the Faculty of Medical Engeneering
of the University of Rome Tor Vergata.
June 2014-August 2015 Research Scholar at Rheumatology laboratory, Arthritis Center, Boston University,
School of Medicine: Scleroderma (Systemic Sclerosis) project.
EDUCATION AND TRAINING
May 2023 Training course organized by: Istituto Zooprofilattico Sperimentale Lazio e Toscana “M.
Aleandri” in collaboration with: Lazio Region, University of Tor Vergata (Rome), Istituto Superiore di Sanità (Rome).
“Animals used for scientific purposes: Oryctolagus cuniculus"
May/November 2022 Training course organized by Istituto Zooprofilattico Sperimentale Lombardia ed Emilia Romagna (IZSLER) ON "LEGISLAZIONE NAZIONALE ED ETICA LIVELLO 1"; "BIOLOGIA E GESTIONE DEGLI ANIMALI DA LABORATORIO"; "ETICA E CONCEZIONE DEI PROGETTI"
22/2/2022 Acquisition of 12 certified credits in Geology (GEO/05) at E-CAMPUS telematic University.
9/11/2021 Acquisition of 24 certified credits in anthropo-psycho-pedagogic topics and in education methods and technologies, at E-CAMPUS telematic University
June 2021 PhD student in Medical-Surgery Biotechnologies and Translational Medicine – XXXIII cycle at University of Rome Tor Vergata.
Thesis title: Characterization of EGFL7 expression during endometrial preparation to implantation and its implications in infertility conditions
November 2020 Qualification to the profession of Biologist Senior, University of Cagliari
February 2020 12th Workshop on “3D Advanced In-Vitro Models”, Rome
December 2019 Workshop SIML (Italian Society of Occupational Health) “Rischi per la salute da lavoro e da stili di vita: la medicina di precisione tra potenzialità e prospettive applicative”, Milan
October/November 2019 Training course organized by Istituto Zooprofilattico Sperimentale Lazio and Toscana in collaboration with University of Rome Tor Vergata and CNR: “Welfare of laboratory animals and alternative methods to animal testing”.
October 2018 Workshop “Discovering Organoids: The Journey Of 3D Culture Systems” at the University of Rome Tre.
October 2017 Degree in Medical Biotechnologies at the Faculty of Medicine and Surgery of the University of Rome Tor Vergata (Grade: 110/110 cum laude).
Thesis title: A novel in vitro model for the study of reproductive toxicity of engineered nanomaterials.
PUBLICATIONS
Lacconi V, Massimiani M, Paglione L, Antonaci D, Meneghini C, Klinger FG, Fazleabas A, Stuhlmann H, Rago R, Ticconi C, Campagnolo L.
Characterization of EGFL7 expression in normal endometrium and in the endometrium of women with poor reproductive outcomes.
Hum Reprod.
2023 May 9:dead086.
doi: 10.1093/humrep/dead086.
Epub ahead of print.
PMID: 37159518.
Ciocca M, Marcozzi S, Mariani P, Lacconi V, Di Carlo A, Cinà, L, D.
Rosato-Siri M, Zanon A, Cattelan G, Avancini E, Lugli P, Priya S, Camaioni A, Brown T.M.
A Polymer Bio–Photoelectrolytic Platform for Electrical Signal Measurement and for Light Modulation of Ion Fluxes and Proliferation in a Neuroblastoma Cell Line.
Advanced Nanobiomed Research.
2023 February 5.
https://doi.org/10.1002/anbr.202200127.
Lacconi V, Massimiani M, Paglione L, Messina A, Battistini B, De Filippis P, Magrini A, Pietroiusti A, Campagnolo L.
An improved in vitro model simulating the feto-maternal interface to study developmental effects of potentially toxic compounds: The example of titanium dioxide nanoparticles.
Toxicol Appl Pharmacol.
2022 May 9;446:116056.
doi: 10.1016/j.taap.2022.116056.
Epub ahead of print.
PMID: 35537546.
Manna C, Lacconi V, Rizzo G, De Lorenzo A, Massimiani M.
Placental Dysfunction in Assisted Reproductive Pregnancies: Perinatal, Neonatal and Adult Life Outcomes.
Int J Mol Sci.
2022;23(2):659.
Published 2022 Jan 8.
Camaioni A, Massimiani M, Lacconi V, Magrini A, Salustri A, Sotiriou GA, Singh D, Bitounis D, Bocca B, Pino A, Barone F, Prota V, Iavicoli I, Scimeca M, Bonanno E, Cassee FR, Demokritou P, Pietroiusti A, Campagnolo L.
Silica encapsulation of ZnO nanoparticles reduces their toxicity for cumulus cell-oocyte-complex expansion.
Part Fibre Toxicol.
2021 Sep 3;18(1):33.
doi: 10.1186/s12989-021-00424-z.
PMID: 34479598
Massimiani M, Tiralongo GM, Salvi S, Fruci S, Lacconi V, La Civita F, Mancini M, Stuhlmann H, Valensise H, Campagnolo L.
Treatment of pregnancies complicated by intrauterine growth restriction with nitric oxide donors increases placental expression of Epidermal Growth Factor-Like Domain 7 and improves fetal growth: A pilot study.
Transl Res.
2020 Aug 9:S1931-5244(20)30198-5
Massimiani M, Lacconi V, La Civita F, Ticconi C, Rago R, Campagnolo L.
Molecular Signaling Regulating Endometrium-Blastocyst Crosstalk.
Int J Mol Sci.
2019 Dec 18
Bianchi MG, Campagnolo L, Allegri M, Ortelli S, Blosi M, Chiu M, Taurino G,
Lacconi V, Pietroiusti A, Costa AL, Poland CA, Baird D, Duffin R, Bussolati O,
Bergamaschi E.
Length-dependent toxicity of TiO(2) nanofibers: mitigation via
shortening.
Nanotoxicology.
2019 Nov 15
Farina A, Peruzzi G, Lacconi V, Lenna S, Quarta S, Rosato E, Vestri AR, York
M, Dreyfus DH, Faggioni A, Morrone S, Trojanowska M, Farina GA.
Epstein-Barr
virus lytic infection promotes activation of Toll-like receptor 8 innate immune
response in systemic sclerosis monocytes.
Arthritis Res Ther.
2017
Santarelli R, Granato M, Pentassuglia G, Lacconi V, Gilardini Montani MS, Gonnella R, Tafani M, Torrisi MR, Faggioni A, Cirone M.
“KSHV reduces autophagy in THP-1 cells and in differentiating monocytes by decreasing CAST/calpastatin and ATG5 expression”, Autophagy.
2016 Oct 7
Granato M, Lacconi V, Peddis M, Di Renzo L, Valia S, Rivanera D, Antonelli G, Frati L, Faggioni A, Cirone M.
“Hepatitis C virus present in the sera of infected patients interferes with the autophagic process of monocytes impairing their in-vitro differentiation into dendritic cells”, Biochim Biophys Acta.
2014 Jul
Granato M, Lacconi V, Peddis M, Lotti LV, Renzo LD, Gonnella R, Santarelli R,
Trivedi P, Frati L, D'Orazi G, Faggioni A, Cirone M.
“HSP70 inhibition by 2-
phenylethynesulfonamide induces lysosomal cathepsin D release and
immunogenic cell death in primary effusion lymphoma”, Cell Death Dis.
2013
NATIONAL AND INTERNATIONAL CONFERENCE
Lacconi V, Massimiani M, La Civita F and Campagnolo L.
Characterization of Epidermal Growth Factor Like Domain 7 (EGFL7) expression and its potential involvement in endometrial receptivity.
Congresso SIAI, Padova, 14-16 September 2022.
Oral presentation
Lacconi V, Massimiani M, La Civita F, Camaioni A and Campagnolo L.
Characterization of Epidermal Growth Factor Like Domain 7 (EGFL7) expression and its potential involvement in endometrial receptivity.
Sessione Scientifica Collegio degli Istologi, Via Scarpa, Rome, 25 February 2022.
Oral presentation and Reward Monesi-Rizzoli’s winner
Massimiani M, Lacconi V, Salustri A, Bocca B, Barone F, Scimeca M, Demokritou P, Camaioni A and Campagnolo L.
Silica Encapsulation of ZnO nanoparticles reduces their toxicity for cumulus cell-oocyte maturation.
Sessione Scientifica Collegio degli Istologi, Via Scarpa, Rome, 26 October 2020.
Oral presentation
Lacconi V, Massimiani M, Rago R, Ticconi C and Campagnolo L.
The secreted factor Epidermal Growth Factor Like Domain 7 (EGFL7): a potential regulator of endometrial receptivity.
Sessione Scientifica Collegio degli Istologi, Via Scarpa, Rome, 26 October 2020.
Oral presentation
Campagnolo L, Lacconi V, La Civita F, Antonaci D, Meneghini C, Massimiani M, Ticconi C, Rago R.
The EGFL7/NOTCH pathway: a novel regulator of the endometrium-blastocyst dialog.
35th Annual meeting on ESHRE, Vienna, Austria, 23-26 June 2019.
Poster.
Tiralongo GM, Massimiani M, Lo Presti D, Cremona A, Lacconi V, Campagnolo L, Valensise H.
A pilot study of fetal growth, maternal hemodynamics and plasma and placental expression of Epidermal Growth Factor Like Domain 7 in pregnancies complicated by fetal growth restriction treated with nitric oxide donors.
3rd International Congress on Maternal Haemodynamics, Cambridge, UK, 12-14 April 2018.
Oral presentation.
Lacconi V, Massimiani M and Campagnolo L.
“In vitro models for the study of reproductive toxicity”.
3RS Winter school: Oltre le barriere...
modelli in vitro per la tossicologia, IZSLER November 2017, Brescia, Oral presentation.
Lacconi V, Massimiani M and Campagnolo L.
In vitro models for the study of reproductive toxicity of engineered nanomaterials.
“Nanoinnovation 2017” San Pietro in Vincoli, Rome, September 26-29, 2017.
Sapienza University of Rome –Faculty of civil and industrial engineering.
Oral presentation.